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Nampt-IN-5

Cat. No.: DC28672

Chemical Structure

2380013-17-0

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Field of application

Nampt-IN-5 is a potent and orally active nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 inhibits CYP3A4 activity and has cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	2380013-17-0
Formula:	C₂₅H₂₅N₅O₂
M.Wt:	427.5
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

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MSDS_12724_DC28672_2380013-17-0

COA

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Cat. No.	Product name	Field of application
DC28969	GPP78	GPP78 (CAY10618) is a potent Nampt inhibitor with an IC50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC50 of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects.
DC28672	Nampt-IN-5	Nampt-IN-5 is a potent and orally active nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 inhibits CYP3A4 activity and has cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.