| DC20294 |
1835F03 |
1835F03 is a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus, inhibits the growth of a panel of S aureus strains (MIC=1-3 ug/mL), including clinical MRSA isolates.. |
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| DC11401 |
1A-116
Featured
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1A-116 is a specific Rac1 inhibitor. |
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| DC5144 |
1-Azakenpaullone
Featured
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1-Azakenpaullone is a potent and ATP-competitive GSK-3β (glycogen synthase kinase-3β) inhibitor (IC₅₀ = 18 nM). |
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| DC23261 |
1E7-03 |
1E7-03 is a small molecule targeting the RVxF interacting site on PP1, inhibits HIV-1, Ebolavirus (EBOV), and Venezuelan equine encephalitis virus (VEEV, EC50=0.6 uM). |
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| DC10674 |
1-EBIO
Featured
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1-EBIO is an Epithelial KCa channel activator. Promotes ESC differentiation into cardiomyocytes. |
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| DC12129 |
1F-Fructofuranosylnystose
Featured
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1F-Fructofuranosylnystose can be used in the synthesis of Fructooligosaccharides (FOSs). Fructooligosaccharides exhibit lots of beneficial effects on our health and have been used as food ingredients. |
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| DC9220 |
1-Kestose
Featured
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1-Kestose is a fructo-oligosaccharide (FOS) with prebiotic properties, and is a polymer of d-fructose joined by β(2→1) linkages and terminated with a d-glucose molecule linked to fructose by an α(1→2) bond as in sucrose. |
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| DC8835 |
1-Methoxy PMS
Featured
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1-Methoxy PMS is an electron mediator for NAD(P)H-tetrazolium salt. |
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| DC8649 |
1-Methyl-7-nitroisatoic anhydride
Featured
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1-methyl-7-nitroisatoic anhydride is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity. |
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| DC9281 |
1-NA-PP1
Featured
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1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). |
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| DC10889 |
1-NA-PP 1 hydrochloride
Featured
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1-Naphthyl PP1(1-NA-PP1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. |
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| DC8640 |
1-NM-PP1
Featured
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1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. |
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| DCAPI1554 |
1α,25-Dihydroxy Vitamin D2 |
1α,25-Dihydroxyvitamin D2 is an active metabolite of vitamin D. It is known that 1α,25-Dihydroxyvitamin D2 can be detected in human serum using high-performance liquid chromatography and ultraviolet detection. Vitamin D2, known as ergocalciferol, is a fat |
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| DCAPI1534 |
Alfacalcidol
Featured
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1α-Hydroxyvitamin D3 is a form of vitamin D that helps the body absorb calcium from food. |
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| DCAPI1471 |
Arabinofuranosylcytosine
Featured
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1-β-D-Arabinofuranosylcytosine, a cytosine analogue, inhibits DNA polymerases α, δ, and ε, and RNA polymerases resulting in suppression of DNA synthesis and repair. 1-β-D-Arabinofuranosylcytosine acts as an antimetabolic agent which is responsible for dam |
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| DC10184 |
2-(Pyridyldithio)ethylamine hydrochloride |
2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfideintercalating cross-linking reagent. |
ethylamine hydrochloride.gif)
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| DC20140 |
Cyclouridine
Featured
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2,2'-Cyclouridine is a research tool for antiviral and anticancer studies. |
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| DC7972 |
2,4-Pyrimidinediamine with linker
Featured
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2,4-Pyrimidinediamine with linker is a patent compound in WO2013055780A1, Page 71; multikinase inhibitor and has a -NH2 terminal linker for further synthesis. |
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| DC23878 |
20(S)-Hydroxycholesterol |
20(S)-Hydroxycholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein, binds at a site distinct from the canonical cyclopamine binding site. |
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| DC9647 |
20-Deoxyingenol
Featured
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20-Deoxyingenol is a natural compound. |
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| DC9655 |
20-O-Acetylingenol-3-angelate
Featured
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20-O-Acetylingenol-3-angelate is a diterpene ester that has been found in E. peplus and a derivative of ingenol-3-angelate |
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| DC23871 |
22-Azacholesterol |
22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells.. |
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| DC10666 |
MDK-7933
Featured
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MDK-7933, also known as HDAC8-IN-1, is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). MDK-7933 was first reported in ChemMedChem. 2012 Oct;7(10):1815-24. MDK-7933 has CAS#1417997-93-3. |
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| DCAPI1409 |
Maxacalcitol |
22-Oxacalcitriol is a Vitamin D3 analog which is Non-calcemic as well as a VDR ligand. 22-Oxacalcitriol has been shown to decrease parathyroid hormone (PTH) mRNA expression in vitro. Additionally has been noted to exhibit similar effects to calcitriol in |
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| DC12367 |
Cyclic guanosine monophosphate-adenosine monophosphate
Featured
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2'3'-cGAMP has been used to identify small compounds capable of binding human stimulator of interferon genes (STING). It is also used to study type I interferon response to cytosolic DNA. |
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| DC9802 |
23-hydroxy butulinic acid (23-HBA)
Featured
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23-hydroxy butulinic acid (23-HBA) is a potent angiogenesis inhibitor. |
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| DC12231 |
25-Hydroxycholesterol
Featured
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25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells. |
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| DCAPI1508 |
25-OH-VD2 |
25-Hydroxyvitamin D2 is used in serum to measure the concentration of vitamin D produced by the skin. It is known that 25-Hydroxyvitamin D2 can be detected in human serum using high-performance liquid chromatography and ultraviolet detection. Vitamin D2, |
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| DC20210 |
2-Aminoethanethiol;cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine |
2-Aminoethanethiol (cysteamine) is a radiation-protective agent that oxidizes in air to form cystamine. |
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| DC22088 |
2BAct
Featured
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2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays. |
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