| DC10452 |
3PO
Featured
|
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor; reduces glycolytic flux and suppresses glucose uptake. |
|
| DC12664 |
3-pyridine toxoflavin
Featured
|
3-pyridine toxoflavin is an impurity of toxoflavin. |
|
| DC10616 |
3-TYP
Featured
|
3-TYP is a selective SIRT3 inhibitor. |
|
| DC22400 |
4-BBPB maleate |
4-BBPB maleate is a highly potent agonist of σ1 receptor with Ki of 0.8 nM. |
|
| DC20186 |
4-Butylresorcinol
Featured
|
4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent. |
|
| DC10644 |
α-CHCA |
4-Chloro-α-cyanocinnamic acid (α-CHCA) is a classic monocarboxylate transporters (MCT) inhibitor. α-cyano-4-hydroxycinnamate (CHC) has a 10-fold selectivity for MCT1 compared to other MCTs. |
|
| DC21978 |
4-CPPC
Featured
|
4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1. |
|
| DC8245 |
4E1rcat
Featured
|
4E1RCat is an inhibitor of protein translation that has been shown to prevent eIF4E:eIF4G and eIF4E:4E-BP1 interaction. |
|
| DC10415 |
4E2RCat
Featured
|
4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM. |
|
| DC7349 |
4EGI-1
Featured
|
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM. |
|
| DC20167 |
4-Hydroxyquinazoline;Quinazolin-4-ol, 4-Quinazolinol |
4-Hydroxyquinazoline is a PARP inhibitor with a high potency for PARP-1 and no effects on enzymes other than PARP. |
|
| DC12067 |
4'-Methylchrysoeriol |
4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. |
|
| DC9978 |
4-oxo-4-HPR
Featured
|
4-oxo-4-HPR is a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. |
|
| DC10090 |
4-P-PDOT
Featured
|
4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype. |
|
| DC10689 |
4P-PDOT
Featured
|
4P-PDOT, also known as 4-phenyl-2- propionamidotetralin, is a MT2-receptor-specific antagonist. MT2 melatonin receptor may be a novel target for analgesic drug development. |
|
| DC8423 |
4SC-202 free base |
4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1. |
|
| DC7592 |
4SC-202
Featured
|
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an acc |
|
| DC10037 |
4μ8C
Featured
|
4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM. |
|
| DC10877 |
5,3-AB-CHMFUPPYCA
Featured
|
5,3-AB-CHMFUPPYCA is an analytical reference standard that is structurally classified as a synthetic cannabinoid. |
|
| DC9997 |
5,6-Dihydro-5-azacytidine |
5,6-Dihydro-5-azacytidine|cas 62488-57-7 |
|
| DCAPI1240 |
5-Aminolevulinic acid HCl |
5-Aminolevulinic acid HCl |
|
| DCAPI1525 |
5-Azacytidine
Featured
|
5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t |
|
| DC20202 |
5-Bromoindole |
5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3). |
|
| DC20168 |
5'-Cytidylic acid; Cytidine monophosphate, Cytidine 5'-phosphate |
5'-Cytidylic acid is a nucleotide that is used as a monomer in RNA. |
|
| DC9371 |
5-FAM SE
Featured
|
5-FAM SE is a single isomer, it is one of the most popular green fluorescent reagents used for labeling peptides, proteins and nucleotides. |
|
| DC8944 |
5-Fluorouracil |
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. |
|
| DC12703 |
5-Formyl-2-pyrimidinecarbonitrile
Featured
|
5-Formyl-2-pyrimidinecarbonitrile is a chemical intermidate.. |
|
| DC12335 |
5'-GTP trisodium salt hydrate (Guanosine 5'-triphosphate trisodium salt hydrate) |
5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. |
|
| DC7494 |
SB-242084 HCl
Featured
|
5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2Breceptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity. |
|
| DC5179 |
5-IODOTUBERCIDIN
Featured
|
5-Iodotubercidin (Itu) has been shown to inhibit mitogen-activated protein kinase (ERK2) (Ki = 525 nM), adenosine kinase (ADK) (Ki = 30 nM), casein kinases 1 & 2 (CSNK1A1 & CSNK2A1), protein kinase A (PKA) and insulin receptor kinase (IC50 ranging from 0. |
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