| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21638 | SLV peptide | A tripeptide representing the Fas-C terminus that specifically blocks the interaction of Fap1 with Fas. |
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| DC24136 | Amitifadine hydrochloride | A triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
|
| DC22736 | Amitifadine | A triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively. |
|
| DC21185 | Cucurbitacin I | A triterpenoid compound that potently and selectively inhibits JAK/STAT3 pathway, suppresses the levels of phosphotyrosine STAT3 in A549 cell with IC50 of 500 nM. |
|
| DC23062 | RAMX3 | A tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM. |
|
| DC22473 | Loxapine | A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.. |
|
| DC22477 | Loxapine succinate | A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.. |
|
| DC8197 | Tyrosine kinase inhibitor Featured | A Tyrosine kinase inhibitor. |
|
| DC22811 | TX-1123 | A tyrphostin AG17 analog that exihibits potent Src-K inhibitory activity with IC50 of 2.2 uM. |
|
| DC24189 | Closantel sodium | A veterinary anthelmintic with known proton ionophore activities. |
|
| DC24190 | Closantel | A veterinary anthelmintic with known proton ionophore activities. |
|
| DC23096 | BCX-4430 | A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator. |
|
| DC25095 | BCX4430 freebase | A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator. |
|
| DC22579 | Retaspimycin hydrochloride | A water-soluble derivative of 17-AAG and HSP90 inhibitor. |
|
| DC22983 | Minnelide | A water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival. |
|
| DC22868 | Propofol | A widely used general anesthetic to induce and maintain anesthesia. |
|
| DC23233 | AH 6809 Featured | A xanthone derivative that fuctions as an EP and DP receptor antagonist. |
|
| DC22878 | LB-205 | A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo. |
|
| DC11491 | A-1048400 | A-1048400(A 1048400) is a novel potent, selective, orally active N-type and T-type calcium channel blocker with IC50 of 1.4 and 1.2 uM, respectively. |
|
| DC9768 | A1155463 Featured | A-1155463 is a highly potent and selective BCL-XL inhibitor. |
|
| DC8475 | A-1210477 Featured | A-1210477 is a potent and selective MCL-1 inhibitor. |
|
| DC10920 | A12B4C3 | A12B4C3 (hPNKP inhibitor A12B4C3) is a specific, noncompetitive inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase (hPNKP) with C50 of 60 nM, displays no inhibition of calcineurin and protein phosphatase-1 or APTX. |
|
| DC9296 | A-1331852 Featured | A-1331852 is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL. |
|
| DC12702 | A1874 Featured | A1874 (A-1874) is a nutlin-based and BRD4-degrading PROTAC with DC50 of 32 nM (induce BRD4 degradation in cells). |
|
| DC10509 | A-196 Featured | A-196 is a potent and selective chemical inhibitor of SUV420H1 and SUV420H2 that inhibits the di- and trimethylation of H4K20me in multiple cell lines. |
|
| DC7044 | A-205804 | A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively. |
|
| DC9574 | A-317491 (sodium salt hydrate) Featured | A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors. |
|
| DC11490 | A-317567 | A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM. |
|
| DC23659 | A-357300 | A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM, does not inhibit MetAP1 or leucine aminopeptidases at 10 uM. |
|
| DC7855 | A-366 Featured | A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM). |
|
