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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC11510 FR-900359 A specific, membrane-permeable inhibitor of Gq signaling.
DC20643 ADDA 5 A specific, non-competitive, small molecule cytochrome c oxidase (CcO or complex IV) inhibitor with IC50 of 18.93 uM (CcO from human glioma).
DC23301 Bax activator compound 106 A specific, small molecule Bax agonist that promotes Bax-dependent but not Bak-dependent apoptosis.
DC24150 Griseofulvin A spirocyclic fungal natural product used in treatment of fungal dermatophytes..
DCAPI1583 liranaftate A squalene epoxidase inhibitor that is used as an antifungal agent.
DC22669 ONO-1301 Featured A stable, orally active, non-prostanoid prostacyclin I2 (PGI2) mimetic and prostacyclin agonist with inhibitory activity against thromboxane A2 synthase.
DC26088 Stauprimide A staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2, which in turn results in down-regulation of MYC transcription.
DC22385 Adrenosterone A steroid hormone with a weak androgenic effect, and an intermediate/prohormone of 11-ketotestosterone..
DC23926 Fiacitabine A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent.
DC24191 Cyclophosphamide hydrate Featured A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
DC22562 OABK hydrochloride A synthetic amino acid that fuctions as a small molecule switch for activation of protein function through the site-specific incorporation.
DC22546 Antibiotic-5d A synthetic antimicrobial compound that antibacterial activity in vitro against various Gram-positive and Gram-negative bacteria, fungi and yeast..
DC23906 Butenafine hydrochloride Featured A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.
DC20656 AM-2201 A synthetic cannabinoid that acts as a potent, nonselective full agonist for the cannabinoid receptor with EC50 of 38 and 58 nM for CB1 and CB2, respectively.
DC23209 HO-3867 Featured A synthetic curcuminoid that selectively inhibits STAT3 phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs.
DC11517 Benzodrocortisone A synthetic glucocorticoid corticosteroid..
DC11525 Mocravimod A synthetic immunosuppressant that functions as a S1P1 receptor agonist.
DC23705 Lenabasum A synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ.
DC22494 ST-2825 A synthetic peptido-mimetic compound that inhibits MyD88 dimerization in a TIR-dependent manner.
DC22357 Benfotiamine A synthetic S-acyl derivative of thiamine (vitamin B1) that possesses anti-inflammatory effects.
DC22458 RX-055 A tailored WOBE437-derived diazirine-containing photoaffinity probe that irreversibly blocks membrane transport of both endocannabinoids.
DC22474 Demeclocycline hydrochloride A tetracycline antibiotic that acts by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA which impairs protein synthesis by bacteria.
DC23965 Clopidogrel thiolactone Featured A thienopyridine-class antiplatelet agent that works by irreversibly inhibiting P2Y12 receptor on platelets.
DC7517 THIACETAZONE Featured A thiosemicarbazone that is used in association with other antimycobacterial agents in the initial and continuation phases of antituberculosis regimens. Thiacetazone containing regimens are less effective than the short-course regimen recommended by the I
DC25059 BMS-986001 A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM.
DC9633 Toll-like receptor modulator A Toll-like receptor modulator.
DC24097 Ufenamate A topical analgesic that possesses anti-inflammatory effect for treatment of skin diseases, such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliaria and atopic dermatitis..
DC22457 NAPQI Featured A toxic byproduct, iminoquinone metabolite of acetaminophen that covalently binds to the active site of MIF.
DC24092 Posaconazole hydrate Featured A triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole..
DC21517 Mithramycin A A tricyclic pentaglycosidic, antineoplastic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA.

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