| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC8642 | Lorediplon Featured | Lorediplon is a new GABAA modulator Drug for treatment of insomnia. |
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| DC10765 | LX-2761 | LX2761 is a locally acting SGLT1 inhibitor that is highly potent in vitro and delays intestinal glucose absorption in vivo to improve glycemic control. |
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| DC7921 | Sotagliflozin (LX-4211) Featured | LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents. |
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| DC2018 | LY335979 (Zosuquidar 3HCl) Featured | LY335979 (Zosuquidar) is a potent modulator of P-glycoprotein-mediated multidrug resistance with Ki of 60 nM. |
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| DC9190 | Manidipine Dihydrochlorid | Manidipine 2Hcl (CV-4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM. |
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| DC11315 | Manidipine(CV-4093) | Manidipine is a dihydropyridine L- and T-type calcium channel blocker. |
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| DC8378 | Mavatrep(JNJ-39439335) Featured | Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6. |
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| DC7194 | MDL 29951 Featured | MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo. |
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| DC8974 | Mexiletine Hydrochloride Featured | Mexiletine hydrochloride is a non-selective voltage-gated sodium channel blocker; Class IB anti-arrhythmic compound. |
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| DC10013 | Mirogabalin Featured | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
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| DC10532 | Mirogabalin besylate Featured | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
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| DC9993 | MK-8998 Featured | MK-8998 is a novel bioactive compound for the treament of psychiatric disease. |
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| DC7998 | ML 204 Featured | ML 204 isa blocker of TRPC4 channels (IC50 values are 0.96 and 2.6 μM in fluorescent and electrophysiological assays, respectively). |
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| DC8850 | ML-213(CID-3111211) Featured | ML-213 (CID-3111211) is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively). |
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| DC7798 | ML-277 Featured | ML-277 is a potent activator of KCNQ1 ( K(v)7.1) channels (EC50 = 260 nM). |
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| DC10849 | ML297 (VU0456810) Featured | ML297 (VU0456810) is the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice. |
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| DC10743 | ml335 Featured | ML335 is a selective activator of both TREK-1 and TREK-2. |
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| DC7797 | ML365 Featured | ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3) with IC50 of 4 nM(thallium influx fluorescent assay) and 16 nM(automated electrophysiology assay). |
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| DC10557 | ML402 Featured | ML402 is a selective TREK-1 activator. |
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| DC9341 | Naspm Featured | Naspm(1-Naphthylacetyl spermine) is a potent and selective Ca2+ permeable AMPA receptor(Ca-perm AMPAR) blocker. IC50 value: Target: CP-AMPAR blocker Naspm is a selective blocker of Ca(2+)-permeable GluA2-lacking AMPA receptors, reduced MNNG-induced CA1 |
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| DC8666 | Nav1.7-IN-2 | Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM. |
|
| DC11406 | NBQX Featured | NBQX is a potent aminomethylphosphonic acid receptor (AMPAR) antagonist with an IC50 of 0.7 ± 0.1 μM. |
|
| DCAPI1574 | Nefiracetam | Nefiracetam is a nootropic of the racetam family. Nefiracetam is cognitive enhancer with an IC50 of approximately 150–200 μM for Ro 5-4864. This compound activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. Nefiracetam di |
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| DC11247 | Nelonicline Featured | Nelonicline (ABT-126) is a potent, selective α7 nicotinic receptor (nAChR) partial agonist for the treatment of cognitive impairment with schizophrenia.. |
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| DC9796 | Nicainoprolhe(Nicainoprol) Featured | Nicainoprolhe is an antiarrhythmic agent,a fast-sodiumchannel blocking drug (class Ib), also protected isolated rat hearts against reperfusion arrhythmias. |
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| DC9170 | Nicardipine hydrochloride | Nicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. |
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| DC8969 | Nicorandil | Nicorandil is potassium channel activator. |
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| DC9131 | Nimodipine | Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. |
|
| DC9108 | Nisoldipine | Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
|
| DC8789 | NS 11021 Featured | NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). |
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