| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10344 | HSP70-IN-1 Featured | HSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM. |
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| DC21149 | HT-0712 | HT-0712 (IPL-455903) is a novel potent, selective PDE4 inhibitor with IC50 of 0.15 uM for PDE4D3, without effect on PDE1B, PDE3A, and PDE10A. |
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| DC21791 | hTG2 inhibitor VA4 | hTG2 inhibitor VA4(VA4) is a novel potent, irreversible inhibitor of human tissue transglutaminase (hTG2) with Ki of 12.9 uM, allosterically abolishs its GTP binding ability with a high degree of selectivity and efficiency. |
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| DC20409 | HTH-01-091 | HTH-01-091 is a potent and selective, cell-permeable, ATP-competitive MELK inhibitor with biochemical IC50 of 10.5 nM. |
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| DC21128 | HTS 01037 | HTS01037 is a highly potent ligand of adipocyte fatty acid binding protein (A-FABP/aP2) with Ki of 0.67 uM. |
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| DC9329 | (±)-Huperzine A | Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). |
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| DC12262 | H-Val-Pro-Pro-OH TFA | H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. |
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| DC20081 | H-Val-Pro-Pro-OH | H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. |
|
| DC11167 | HX600 | HX600 (HX-600) is a synthetic agonist of RXR-Nurr1 heterodimer complex, also selectively activate NGFI-B/RXR heterodimers. |
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| DC20410 | Hydrazinocurcumin Featured | Hydrazinocurcumin is a synthetic curcumin derivative that inhibits the proliferation of bovine aortic endothelial cells (BAECs) with IC50 of 520 nM without cytotoxicity, inhibits STAT3 phosphorylation and downregulates an array of STAT3 downstream targets. |
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| DC10227 | Hydroquinidine | Hydroquinidine is an antiarrhythmic agent. |
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| DC10237 | Hydroxyprogesterone caproate | Hydroxyprogesterone Caproate is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium. |
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| DC11328 | Hydroxyzine | Hydroxyzine is a histamine H1 receptor antagonist (Ki = 1.9 nM). |
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| DC9913 | Hypericin | Hypericin is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum. It can inhibit tyrosine kinases with IC50 of 7.5 μM. |
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| DC21129 | HZ05 | HZ05 is a potent DHODH inhibitor with IC50 of 32 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo.. |
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| DC11118 | HZ-166 | HZ-166 (HZ166) is a GABAA receptor subtype-selective benzodiazepine site ligand with preferential activity at α2- and α3-GABA(A) receptors. |
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| DC8601 | IAA-94 | IAA-94 is an indanyloxyacetic acid blocker of epithelial chloride channels. |
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| DC12105 | IACS-10759 Hydrochloride | IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS). |
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| DC21131 | IACS-4619 | IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.2 nM. |
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| DC21132 | IACS-4759 | IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.6 nM. |
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| DC23352 | IACS-7e | IACS-7e is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement).. |
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| DC23361 | IACS-9571 | IACS-9571 is a potent, selective dual TRIM24-BRPF1 bromodomain inhibitor with Kd of 31 and 14 nM, respectively. |
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| DC23546 | IAXO-102 | IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development. |
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| DC21905 | IBET151-VHL-PROTAC | IBET151-VHL-PROTAC is a novel PROTAC.. |
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| DC12341 | Ibiglustat succinate (Venglustat (succinate); GZ/SAR402671 (succinate)) Featured | Ibiglustat (succinate) is a selective inhibitor of glucosylceramide synthase. |
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| DC7635 | IB-MECA Featured | IB-MECA is a potent and selective A3 adenosine receptor agonist (Ki values are 1.1, 54 and 56 nM for A3, A1 and A2A receptors respectively). |
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| DC21134 | IBR2 | IBR2 is a novel small molecule RAD51 inhibitor that specifically binds to RAD51 and disrupts the BRC repeats of BRCA2/RAD51 interaction with IC50 of 0.11 uM. |
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| DC22112 | IBS003031 | IBS003031 (IBS-003031) is a novel chemical Yes-associated protein 1 (YAP1) activator, up-regulates H2B-mCherry expression at 1 and 3 uM in mCherry signal based reporter assays. |
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| DC8573 | Ibufenac | Ibufenac is an analog of the NSAID ibuprofen that inhibits COX-1 and -2 activity with IC50 values of 17.4 and 13.1 µM, respectively. |
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| DC20411 | Ibulocydine | Ibulocydine is the prodrug of CDK inhibitor BMK-Y101, inhibits CDK7 and CDK9 with IC50 of 530 nM and 85 nM in kinase assays, respectively. |
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