| DC8208 |
OAC1
Featured
|
OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process. |
|
| DC8700 |
ODM-201(Darolutamide)
Featured
|
ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by transactivation assays in AR-HEK293 cells. |
|
| DC8390 |
Oltipraz
Featured
|
Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3. |
|
| DC11203 |
ORIC-101
Featured
|
ORIC-101 (ORIC101) is a highly potent, selective steroidal glucocorticoid receptor (GR) antagonist (IC50=5.6 nM) with reduced androgen receptor (AR) agonistic activity. |
|
| DC8690 |
ORM-15341(Ketodarolutamide)
Featured
|
ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. |
|
| DC8248 |
Ostarine(MK-2286)
Featured
|
Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism. |
|
| DC9897 |
Palmitoylethanolamide |
Palmitoylethanolamide(PEA) is an endogenous fatty acid amide and selectively activates PPAR-α in vitro with an EC50 value of 3.1±0.4 μM. |
|
| DC6577 |
Paricalcitol |
Paricalcitol |
|
| DC11360 |
Pemafibrate
Featured
|
Pemafibrate is an orally bioavailable and selective agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 1 nM for transcriptional activity), a transcription factor that is essential for regulation of lipid homeostasis. |
|
| DC11224 |
PF-06747711 |
PF-06747711 (PF06747711) is a potent, selective, orally bioavailable RORC2 (RORγt) inverse agonist with IC50 of 4.1 nM. |
|
| DC10846 |
PHTPP
Featured
|
PHTPP is a pyrazolo[1,5-α]pyrimidine-based ligand that acts as a full antagonist of estrogen ERβ receptors with 36-fold selectivity over ERα. |
|
| DCAPI1413 |
pioglitazone hydrochloride
Featured
|
Pioglitazone Hydrochloride is the hydrochloride salt preparation of Pioglitazone, a specific ligand of PPAR-γ (peroxisome proliferator-activated receptor-γ). Pioglitazone is a thiazolidinedione compound described to produce antiinflammatory and antiarteri |
|
| DC10464 |
PT2385
Featured
|
PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential antineoplastic activity. |
|
| DC9811 |
PT2399
Featured
|
PT2399(PT=2399) is a novel HIF2α Antagonist. |
|
| DC7486 |
PX-478 2HCL
Featured
|
PX-478 is an inhibitor of HIF-1a with an IC50 of 20-30μM enhances radiosensitivity of prostate carcinoma cells. |
|
| DC9657 |
RAD140
Featured
|
RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). |
|
| DCAPI1577 |
Raloxifene |
Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM), binding to ERα and ERβ. Tissue-dependently blocks or activates estrogen-induced transcription. Exhibits estrogen agonist behavior in bone but acts as an anti-estrogen in breast an |
|
| DC11430 |
RB-394 |
RB394 is an orally bioavailable and dual modulator of soluble epoxide hydrolase (sEH) and PPARγ. |
|
| DC10993 |
RD162
Featured
|
RD162 is a second-generation, orally available antiandrogen that binds to androgen receptor (AR) with IC50 of 30.9 nM. |
|
| DC11054 |
RORγt inverse agonist 22 |
RORγt inverse agonist 22 is a potent, subtype selective RORγt inverse agonist with binding IC50 of 18 nM, displays >192-fold selectivity over RORα and RORβ. |
|
| DC11202 |
RORγt inverse agonist 32 |
RORγt inverse agonist 32 is a potent, orally bioavailable inverse agonist of RORγt with IC50 of 9 nM in SPA binding assays. |
|
| DCAPI1480 |
rosiglitazone maleate
Featured
|
Rosiglitazone maleate is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits T |
|
| DC9084 |
Rosiglitazone base |
Rosiglitazone(BRL-49653) is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ(PPARγ). |
|
| DC8198 |
RTA-408(Omaveloxolone)
Featured
|
RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-κB. |
|
| DC4163 |
RU58841
Featured
|
RU58841 is a nonsteroidal anti-androgen with potency (IC50 = 100 nM, Ka = 1.1 nM) comparable to hydroxyflutamide. |
|
| DC10811 |
S23
Featured
|
S23 is a novel Selective Androgen Receptor Modulator(SARM) |
|
| DC11684 |
sAJM-589 |
sAJM-589 is a novel, potent small molecule Myc inhibitor that disrupts the Myc-Max leucine-zipper heterodimer with IC50 of 1.8 uM. |
|
| DC10470 |
SB756050
Featured
|
SB-756050 is a Farnesoid X receptor (FXR) (NR1H4) agonist. |
|
| DCAPI1546 |
Secalciferol |
Secalciferol |
|
| DC10700 |
Seladelpar
Featured
|
Seladelpar is a selective peroxisome proliferator-activated receptor (SPPAR) -δ receptor agonist. |
|
