| DC20875 |
CCT 365623 hydrochloride |
CCT 365623 (CCT365623) hydrochloride is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
|
| DC20874 |
CCT 365623 |
CCT 365623(CCT365623, CCT-365623) is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
|
| DC7803 |
CCT007093
Featured
|
CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. |
|
| DC22464 |
CCT-018159 |
CCT-01815 is a novel potent inhibitor of Hsp90 ATPase activity with IC50 of 7.1 uM. |
|
| DC20872 |
CCT-031374 |
CCT-031374 is a selective β-catenin signaling inhibitor with IC50 of 6.1 uM. |
|
| DC23168 |
CCT128930 |
CCT128930 is a potent, selective, ATP-competitive AKT inhibitor with IC50 of 6 nM (AKT2), 28-fold selectivity over the closely related PKA. |
|
| DC23163 |
CCT129202
Featured
|
CCT129202 is a potent, selective, ATP-competitive pan-Aurora kinase inhibitor with IC50 of 42, 198 and 227 nM for Aurora A, Aurora B and Aurora C, respectively. |
|
| DC23828 |
CCT241161 |
CCT241161 is a potent pan-RAF inhibitor with IC50 of 30, 15 and 6 nM for BRAF, V600E-BRAF and C-RAF, also potently inhibits SRC and LCK (IC50=10 and 3 nM, respectively).. |
|
| DC10911 |
CCT241736
Featured
|
CCT241736 is a novel, orally bioavailable Dual FLT3-Aurora Kinase Inhibitor. |
|
| DC12549 |
CCX-354 |
CCX-354 (GSK-2941266, CCX354-C, CCX354) is a potent, selective, orally-available CCR1 antagonist for the treatment of inflammatory diseases such as rheumatoid arthritis (RA).. |
|
| DC20332 |
CD38 inhibitor 78c
Featured
|
CD38 inhibitor 78c is a potent, specific, reversible CD38 inhibitor with Ki of 14.5 nM for recombinant human CD38. |
|
| DC20877 |
S8 |
Cdc25 inhibitor S8 is an anti-fungal small molecule that inhibits cdc25 phosphatase with Ki of 140 uM. |
|
| DC21877 |
Cdc7 inhibitor |
Cdc7 inhibitor is a potent inhibitor of Cdc7 kinase with pIC50 of 10.01 against CDC7/DBF4 in TR-FRET assays.. |
|
| DC22051 |
CDD-450 |
CDD-450 is an unique inhibitor that selectively blocks p38α activation of proinflammatory kinase MAPK-MK2 while sparing p38α activation of PRAK and ATF2. |
|
| DC8361 |
CDDO(Bardoxolone; RTA 401)
Featured
|
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. |
|
| DC12026 |
CDDO-2P-Imidazolide
Featured
|
CDDO-2P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid. |
|
| DC12027 |
CDDO-3P-Imidazolide
Featured
|
CDDO-3P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid. |
|
| DC20334 |
CDK2 inhibitor 73
Featured
|
CDK2 inhibitor 73 is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).. |
|
| DC20921 |
CDK5 inhibitor 20-223 |
CDK5 inhibitor 20-223 (CP 668863) potent, selective, ATP-competitive CDK2/5 inhibitor with IC50 of 6.0 and 8.8 nM for CDK2/CyclinE and CDK5/p35, with little to no activity against CDK1/4/6/7/9. |
|
| DC12528 |
CDK9 inhibitor HH1
Featured
|
CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor.. |
|
| DC20335 |
CDK9-IN-8
Featured
|
CDK9-IN-8 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition. |
|
| DC23138 |
CDK-I73
Featured
|
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM. |
|
| DC11393 |
CDM-NAG
Featured
|
CDM-NAG is a useful tool compound to deliver the siRNA. |
|
| DC20879 |
CDP-840 |
CDP-840 (CDP840. |
|
| DC20880 |
CDP-840 hydrochloride |
CDP-840 (CDP840. |
|
| DC23463 |
CDPPB
Featured
|
CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively. |
|
| DC22446 |
CE-224535 |
CE-224535 (PF-04905428) is a potent and selective P2X7 receptor antagonist with IC50 of 1.4 nM (inhibition of the release of lL-1b from monocytes stimulated by ATP). |
|
| DC20881 |
CE-245677 |
CE-245677 is a potent, selective, orally active, dual Tie2/Trk kinase inhibitor with IC50 of 4.7 nM, 1 nM for Tie2 and TrkA/B, respectively. |
|
| DC20336 |
CE3F4
Featured
|
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
|
| DC23912 |
Cecropin B |
Cecropin B is an antimicrobial peptide with MICs(0.5 to 16 ug/ml) against Gramnegative strains. |
|
