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| Cas No.: | 2079895-42-2 |
| Chemical Name: | 4-{[6-(3-Biphenylyl)-7H-purin-2-yl]amino}benzenesulfonamide |
| Synonyms: | CDK2 inhibitor 73;CDK2-IN-4;4-[[6-(3-Phenylphenyl)-7~{h}-Purin-2-Yl]amino]benzenesulfonamide;BCP32769;BDBM50235334;72L;4-{[6-(3-Biphenylyl)-7H-purin-2-yl]amino}benzenesulfonamide |
| SMILES: | C1=NC2=NC(N([H])C3C=CC(S(N([H])[H])(=O)=O)=CC=3)=NC(C3C=C(C4C=CC=CC=4)C=CC=3)=C2N1[H] |
| Formula: | C23H18N6O2S |
| M.Wt: | 442.493022441864 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | CDK2-IN-4 is a potent and selective CDK2 inhibitor with an IC50 of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM)[1]. |
| References: | [1]. Coxon CR, et al. Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J Med Chem. 2017 Mar 9;60(5):1746-1767. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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| 2018-0101 |
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