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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC20401 HDAC6-AR-IN-10 HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM).
DC21113 HEC72702 HEC72702 is a novel potent, orally active inhibitor of HBV capsid assembly, inhibits HBV-DNA levels in HepG.2.2.15 cells with IC50 of 39 nM.
DC21114 HEC-73543 HEC-73543 is a novel potent, selective, orally bioavailable FLT3 inhibitor for the treatment of refractory acute myeloid leukemia (AML).
DC9921 Hederacoside C Featured Hederacoside C is a principal bioactive pharmaceutical ingredient of Hedera helix leaf that can treat respiratory disorders, because of its expectorant, bronchodilator, antibacterial, and bronchospasmolytic effects.
DC9823 Hederagenin Featured Hederagenin a triterpenoid saponin, is used to study the properties of triterpenoid saponins as biopesticides that prevent fungal growth, bacterial growth, and viral plant diseases.
DC20402 Hedgehog-IN-7d Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM..
DC21414 Helenalin Helenalin (NSC 85236) is a sesquiterpene lactone that covalently targets Cys38 on p65 transcription factor in the canonical NF-κB signaling pathway.
DC21109 Hemicholinium-3 Hemicholinium-3 (HC-3) is a competitive, small molecule inhibitor of choline kinase (ChoK) with ex vivo IC50 of 500 uM, also bolcks the sodium and chloride-dependent transport system and affects choline acetyltransferase.
DC24152 Hemin Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.
DC21115 TD-1 Featured Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling.
DC12294 Heparin lithium salt Featured Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII).
DC10422 Heptamethine cyanine dye-1 Heptamethine cyanine dye-1 is a near-infrared cyanine dye for fluorescence imaging in biological systems.
DC20403 HER2-IN-2 HER2-IN-2 is a potent, selective HER2 inhibitor, only shows potent inhibition for EGFR and Abl in a panel of kinases.
DC20404 HER2-IN-3 HER2-IN-3 is a type I HER2 inhibitor that has a similar profile to HER2-IN-2.
DC23730 Herboxidiene Herboxidiene (GEX1A, TAN-1609) is a polyketide molecule first isolated from the fermentation broth of Streptomyces chromofuscus, shows in vitro antitumor activity by targeting the SF3B protein in the splicesosome.
DCAPI1218 Hesperidin Hesperidin
DC12717 Hetrombopag Hetrombopag is a potent, selective, orally-active Thrombopoietin (TPO) receptor agonist.
DC12227 Hexacosanoic acid Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
DC12195 Hexadimethrine bromide Featured Hexadimethrine bromide is a cationic polymer discovered to enhance retroviral transduction.
DC12306 Hexamethylquercetagetin Hexamethylquercetagetin is a polymethoxylated flavone in peels of citrus cultivars.
DC8680 Hexaminolevulinate hydrochloride Hexaminolevulinate hydrochloride is a fluorescent agent, has approved for cystoscopic detection of papillary bladder cancer.
DC12707 Hexokinase 2 modulator Comp-1 Hexokinase 2 modulator Comp-1 is a potent, selective small molecule modulator of Hexokinase 2 (HK2) interaction with the mitochondria, selectively dissociates HK2 from VDAC1 in vitro with IC50 of 92 nM.
DC21904 HG-12-6 HG-12-6 is a small-molecule inhibitor that bind preferentially to unphosphorylated IRAK4 with IC50 of 165.1 nM, displays 15-fold selectivity over phosphorylated IRAK4 (IC50=2876 nM).
DC10652 HG-14-10-04 Featured HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.
DC23141 HG6-64-1 HG6-64-1 is a potent dual TAK1 and MAP4K2 ((germinal center kinase, GCK)) inhibitor with IC50 of 41 nM and 98 nM, respectively.
DC20405 HG-7-27-01 HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases..
DC21379 HG-7-92-01(NG25) Featured HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases..
DC10108 HG-9-91-01 Featured HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively.
DC26060 gly-arg p-nitroanilide dihydrochloride Featured H-Gly-Arg-pNA is a colorimetric substrate for thrombin.
DC8846 HhAntag Featured HhAntag is a GLI1-Mediated transcription inhibitor.

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