| DC22147 |
MGV354 R-form |
MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.. |
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| DC22146 |
MGV354
Featured
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MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.. |
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| DC8074 |
MHY1485
Featured
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MHY1485 is mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. |
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| DC23290 |
MI 219 |
MI 219 is a potent, specific MDM2-p53 inhibitor with Ki of 5 nM, >10,000-fold selective for MDM2 over MDMX. |
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| DC22148 |
MI-1481 |
MI-1481 (MI1481) is a highly potent inhibitor of the menin-MLL1 interaction with IC50 of 3.6 nM, 10-fold increase in inhibitory activity over MI-463 and MI-503. |
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| DC20450 |
MI-2-2 hydrochloride |
MI-2-2 hydrochloride is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM). |
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| DC20449 |
MI-2-2
Featured
|
MI-2-2 is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM); inhibits the interaction of menin with MLL-AF9 in HEK293 cells in a dose-dependent manner with 4-fold potentcy improvement over MI-2; suppresses growth of MLL-AF9–transformed BMCs; causes MV4:11 cells growth inhibition of with GI50 of 3 uM. |
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| DC23291 |
MI-223 |
MI-223 (NSC 320223) is a small molecule that specifically binds to Mcl-1 with Kd of 160 nM, inhibits HR DNA repair and sensitizes cancer cells to DNA replication agents. |
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| DCAPI1514 |
Micafungin sodium
Featured
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Micafungin(FK463) is an echinocandin antifungal drug, Micafungin inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. |
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| DC11162 |
MID-1
Featured
|
MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction; increases the IRS-1 protein level in C2C12 myotubes, abrogates MG53-induced IRS-1 ubiquitination and degradation; potent |
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| DC20962 |
Midazolam |
Midazolam (Dormicum. |
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| DC23570 |
MIDD0301
Featured
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MIDD0301 is a potent, positive allosteric, α5β3γ2 selective, GABAA receptor (GABAAR) ligand with EC50 of 17 nM, shows no significant binding at the peripheral GABAAR at 10 uM. |
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| DC24075 |
Midodrine
Featured
|
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
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| DC24076 |
Midodrine hydrochloride
Featured
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Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
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| DC20451 |
MIF-IN-3bb |
MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM. |
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| DC10328 |
Migalastat hydrochloride
Featured
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Migalastat hydrochloride (1-Deoxygalactonojirimycin hydrochloride) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. |
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| DCAPI1324 |
Miglitol (Glyset) |
Miglitol (Glyset) |
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| DC9545 |
Miglustat (hydrochloride)
Featured
|
Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). |
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| DC12425 |
MIK665 |
MIK665 (S-64315, MIK-665) is a novel potent, selective Mcl-1 inhibitor with potential pro-apoptotic and antineoplastic activities. |
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| DCAPI1436 |
Milbemycin oxime
Featured
|
Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~70: 30 ratio). Moxidectin oxime, marketed as Interceptor, is used therapeutically for the prev |
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| DCAPI1003 |
Milnacipran HCl |
Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively. |
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| DC9120 |
Miltefosine
Featured
|
Miltefosine is an alkylphosphocholine drug. |
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| DC21074 |
Milveterol |
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold). |
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| DC21075 |
Milveterol hydrochloride |
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold). |
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| DC21584 |
MIN-101
Featured
|
MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.. |
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| DC23395 |
MIND-4 |
MIND-4 is a novel potent, selective, non-competitive SIRT2 deacetylase inhibitor with IC50 of 1.2 uM, Ki of 2.1 uM, and also is an inducer of the NRF2 pathway. |
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| DC8968 |
Minoxidil |
Minoxidil(U 10858) is an antihypertensive vasodilator medication. |
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| DC10152 |
Miquelianin (Quercetin 3-O-glucuronide)
Featured
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Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid. |
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| DC21919 |
MIR17PTi |
MIR17PTi is a novel LNA gapmeR antisense oligonucleotide (LNA-ASO), first-in-class inhibitor of pri-mir-17-92. |
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| DC21651 |
miR544-IN-1 |
miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis. |
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