| DC9569 |
Nefazodone (hydrochloride)
Featured
|
Nefazodone hydrochloride is an antidepressant drug. |
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| DC23246 |
Nef-IN-B9 |
Nef-IN-B9 (Nef inhibitor B9) is a small molecule that blocks Nef-dependent Hck activity with IC50 of 2.8 uM, while the activity against Hck alone is >20 uM. |
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| DCAPI1513 |
Nefopan hydrochloride |
Nefopanhydrochloride |
|
| DC8194 |
PP3
Featured
|
Negative control for the Src kinase inhibitor PP2. |
|
| DC8290 |
(S)-PFI-2 HCl
Featured
|
Negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer. |
|
| DC12465 |
NEK6 inhibitor 8
Featured
|
NEK6 inhibitor 8(ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9. |
|
| DC20743 |
Neladenoson dalanate |
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.. |
|
| DC20744 |
Neladenoson dalanate hydrochloride |
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.. |
|
| DC4129 |
Arranon
Featured
|
Nelarabine (Arranon, 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells. |
|
| DC22175 |
NEO214 |
NEO214 (NEO-214) is a novel, BBB-permeable rolipram-perillyl alcohol conjugate, shows effectivity against both TMZ-sensitive and TMZ-resistant glioma cells (T98G IC50=40 uM). |
|
| DC23087 |
Neoandrographolide
Featured
|
Neoandrographolide has antiradical, anti-inflammatory,and hypolipidemic effects, it protects the cardiovascular without significant liver damage. Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIA |
|
| DC23057 |
Nestorone |
Nestoron2 (ST1435, Elcometrine) is a 19-norprogesterone derivative and steroidal progestin which is used as a hormonal contraceptive, a high-affinity agonist of the progesterone receptor.. |
|
| DC22636 |
Netarsudil dihydrochloride
Featured
|
Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2. |
|
| DC9353 |
Netilmicin (sulfate) |
Netilmicin Sulfate is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin. |
|
| DC8100 |
Netupitant |
Netupitant is a highly potent and selective, orally active neurokinin-1 receptor antagonist with Ki of 0.95 nM. |
|
| DC23275 |
NEU-1953(NEU1953) |
NEU-1953 (NEU1953) is a potent inhibitor of P. falciparum with EC50 of 0.43 uM (T. brucei), demonstrates improved ADME profile over the NEU-961.. |
|
| DC5131 |
Neuropathiazol
Featured
|
Neuropathiazol selectively induces neuronal differentiation of primary hippocampal neural progenitor cells. It is more potent and selective compared to retinoic acid. Also suppresses astrocyte differentiation. |
|
| DC12238 |
Neurotoxin Inhibitor |
Neurotoxin Inhibitor is a neurotoxin inhibitor. |
|
| DC23016 |
Nexinhib 20 |
Nexinhib 20 is a novel small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors. |
|
| DC12660 |
NFAT Inhibitor-1
Featured
|
NFAT inhibitor is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT. |
|
| DC12176 |
NFAT Transcription Factor Regulator
Featured
|
NFAT Transcription Factor Regulator is an IL-2 synthesis inhibitor with an IC50 of 182 nM. |
|
| DC23081 |
NFPS |
NFPS (ALX-5407) is a potent, selective GlyT1 inhibitor with IC50 of 2.8 and 9.8 nM for hGlyT1 and rGlyT1 respectively, >5,000-fold selectivity over rGlyT2. |
|
| DC8076 |
NG 52 (Compound 52 )
Featured
|
NG 52 (Compound 52) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 μM), and the related Pho85p kinase (IC50 = 2 μM). |
|
| DC21380 |
NGD-4715 |
NGD-4715 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1), has anxiolytic, antidepressant and anorectic effects.. |
|
| DC11281 |
NGI-1 (ML414)
Featured
|
NGI-1 (ML414) is a potent, cell-permeable oligosaccharyltransferase (OST) inhibitor with IC50 of 1.1 uM. |
|
| DC11200 |
NGI-1 derivative C-19 |
NGI-1 derivative C-19 is a specific, small-molecule inhibitor of oligosaccharyltransferase (OST) catalytic subunit STT3B, without effect on STT3A. |
|
| DC8525 |
NIBR-17
Featured
|
NIBR-17 is a pan class I PI3K inhibitor with IC50 values of 1, 9.2, 9 and 20 nM respectively for PI3Kapha - delta. |
|
| DC21742 |
NIBR-3049 |
NIBR-3049 (TCS-21311) is a potent, highly selective JAK3 inhibitor with IC50 of 8 nM, displays >100-fold selectivity over JAK1, JAK2 and TYK2, also inhibits PKCα, PKCθ, and GSK3β with IC50 of 13, 68, and 3 nM, respectively.. |
|
| DC7977 |
Nicaraven
Featured
|
Nicaraven is an antivasospastic substance. |
|
| DC25090 |
Nicardipine |
Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.. |
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