| DC9068 |
Niclosamide |
Niclosamide(BAY2353) is used for the treatment of most tapeworm infections by inhibiting DNA replication. |
|
| DC21243 |
Nidufexor（LMB-763）
Featured
|
Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders. |
|
| DC9079 |
Nifedipine |
Nifedipine(Adalat), a potent vasodilator agent with calcium antagonistic action. |
|
| DCAPI1571 |
Nifuratel |
Nifuratel |
|
| DC12297 |
Nigakinone |
Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu. |
|
| DC10028 |
NIH-12848
Featured
|
NIH-12848 (NCGC00012848-02) is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor, was explored as a tool for investigating this enigmatic, low activity, |
|
| DC4192 |
Nilutamide |
Nilutamide is an antiandrogen medication used in the treatment of advanced stage prostate cancer. |
|
| DC9379 |
Nilvadipine |
Nilvadipine(FR34235) is a calcium channel blocker for treatment of hypertension.
|
|
| DC9052 |
Nimesulide |
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. |
|
| DC7758 |
Nimorazole
Featured
|
Nimorazole is a nitroimidazole anti-infective. |
|
| DCAPI1251 |
Nitazoxanide (Alinia, Annita)
Featured
|
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). |
|
| DC21383 |
NITD-304 |
NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv. |
|
| DC21384 |
NITD-349 |
NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv. |
|
| DC21385 |
NITD-564 |
NITD-564 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.59 uM, exhibits MIC50 of 160 nM against Mtb. |
|
| DC21386 |
NITD-916 |
NITD-916 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.57 uM, exhibits MIC50 of 50 nM against Mtb. |
|
| DC9561 |
Nitisinone
Featured
|
Nitisinone(SC0735) is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase.
|
|
| DC9085 |
Nitrendipine |
Nitrendipine is a calcium channel blocker with marked vasodilator action. |
|
| DC21388 |
NJK14047 |
NJK14047 is a novel potent, selective p38 MAPK inhibitor with IC50 of 27 nM against p38α, suppresses RSV and influenza A virus replication by inhibiting virus-induced p38 MAPK activation. |
|
| DC20916 |
NKH 477 hydrochloride
Featured
|
NKH 477 hydrochloride (Colforsin dapropate) is a water-soluble analog of Forskolin and a potent activator of adenylyl cyclase, shows some selectivity for cardiac (type V) adenylyl cyclase. |
|
| DC9786 |
NKP-1339
Featured
|
NKP-1339 is the first-in-class ruthenium-based anticancer drug in clinical development against solid cancer and has recently been studied successfully in a phase I clinical trial. |
|
| DC5172 |
NLG919(GDC-0919)
Featured
|
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM. |
|
| DC26132 |
NLRP3 Inflammasome Inhibitor I |
NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome. |
|
| DC22177 |
NLY01 |
NLY01 (NLY-01, GLP1R agonist NLY01) is a potent, brain-penetrant long-acting GLP1R agonist, protects against the loss of dopaminergic neurons and behavioral deficits in the α-synuclein preformed fibril (α-syn PFF) mouse model of sporadic Parkinson's disea |
|
| DC11134 |
NMac1 |
NMac1 (Nm23 activator 1) is a small molecule activator of Nm23/NDPK, directly binds to Nm23-H1 and activates NDPK activity of recombinant Nm23-H1 with EC50 of 10.7 uM. |
|
| DC20105 |
NMDAR antagonist 1
Featured
|
NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective NMDAR antagonist. |
|
| DC8829 |
Betahistine EP Impurity C(NSC19005)
Featured
|
N-Methyl-N,N-bis(2-pyridylethyl)amine is used as a reagent in the preparation of copper pyridylmethylethylenediamine dicyanamido polymeric complexes. |
|
| DC7212 |
NMS-873
Featured
|
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP). |
|
| DC21390 |
NMS-P293 |
NMS-P293 is a novel potent and selective PARP-1 inhibitor possessing >200-fold selectivity versus PARP-2. |
|
| DC23556 |
NMS-P645 |
NMS-P645 is a novel selective inhibitor of pan-Pim kinases with IC50 of 3/73/12 nM for Pim1/2/3, respectively. |
|
| DC8445 |
NMS-P937 (NMS1286937)
Featured
|
NMS-P937 (NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Phase 1. |
|
