| DCZ-291 |
isorhapontigenin |
purity >98%,Standard References |
|
| DCZ-292 |
TECTOCHRYSIN |
purity >98%,Standard References |
|
| DCZ-290 |
Isobavachin |
purity >98%,Standard References |
|
| DCZ-286 |
8-GERANOPSORALEN |
purity >98%,Standard References |
|
| DCZ-289 |
songorine |
purity >98%,Standard References |
|
| DC8558 |
Puromycin aminonucleoside
Featured
|
Puromycin Aminonucleoside (3'-Amino-3'-deoxy-N6,N6-dimethyladenosine) is the aminonucleoside portion of the antibiotic puromycin. |
|
| DC10169 |
Puromycin
Featured
|
Puromycin is an aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. It is a protein synthesis inhibitor. |
|
| DC23344 |
PVZB-1194 |
PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM. |
|
| DC26129 |
PWT143 (ME-401)
Featured
|
PWT143 (ME-401), is an orally bioavailable inhibitor of the delta isoform of phosphatidylinositide 3-kinase (PI3K), with potential antineoplastic activity. |
|
| DC23657 |
PWZ-029 |
PWZ-029 is a potent, subtype-selective partial inverse agonist of α5 GABAA receptors with Ki of 30 nM, demonstrates memory enhancing effects in vivo. |
|
| DC20222 |
Px-104 |
Px-104(Px-102) is a farnesoid X receptor (FXR) agonist potentially for the treatment of non-alcoholic fatty liver disease. |
|
| DC7992 |
PX 12
Featured
|
PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1(Trx-1) currently in clinical development as an antitumor agent; IC50=7 uM in Hela, MTT assay, 72 h. |
|
| DC10565 |
PX-102(PX-20606) |
PX20606, also known as PX-102, is a FXR agonist. |
|
| DC20519 |
Pyk2-IN-25a |
Pyk2-IN-25a is a highly potent Pyk2 (PTK2B) inhibitor with IC50 of 0.67 nM, dispalys 2-fold weakening potency for FAK (IC50=1.26 nM). |
|
| DC23668 |
PyP-1 |
PyP-1 is a potent, highly selective, and orally bioavailable PDE10A inhibitor with Ki of 0.23 nM. |
|
| DCAPI1405 |
Pyrazinamide (Pyrazinoic acid amide) |
Pyrazinamide (Pyrazinoic acid amide) |
|
| DC22202 |
Pyrazinib |
Pyrazinib (Pyrazinib (P3)) is a pyrazine phenol small molecule drug with anti-angiogenic and anti-metabolic activity in-vivo in zebrafish and in-vitro isogenic models of OAC radioresistance. |
|
| DC8091 |
Pyridostatin trifluoroacetate salt
Featured
|
Pyridostatin stabilizes G-quadruplexes, targeting the proto-oncogene SRC and telomeric G-quadruplexes, inducing DNA damage and cell-cycle arrest. |
|
| DC20241 |
PIH(Pyridoxal isonicotinoyl hydrazine)
Featured
|
Pyridoxal isonicotinoyl hydrazine is a lipophilic, nontoxic, iron-chelating agent that shows high iron chelation efficacy both in vitro in cell culture models and in vivo in rats and mice. |
|
| DC20154 |
Pyridoxine hydrochloride
Featured
|
Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. |
|
| DC20520 |
Pyrimidinone 8 |
Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM. |
|
| DC21547 |
Pyrimidyn 7 |
Pyrimidyn 7 is a potent, dual-action dynamin GTPase activity inhibitor with IC50 of 1.1 uM/1.8 uM for dynamin I/dynamin II respectively, competitively inhibits both GTP and phospholipid interactions with dynamin. |
|
| DC12084 |
Pyronaridine tetraphosphate
Featured
|
Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against drug resistant Plasmodium falciparum, P. vivax, P. ovale and P. malariae. |
|
| DC10691 |
Pyronaridine
Featured
|
Pyronaridine, also known as Malaridine, is an antimalarial drug. |
|
| DC23125 |
Pyrotinib maleate
Featured
|
Pyrotinib maleate (SHR-1258 maleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50 of 13/38 nM, respectively. |
|
| DC10810 |
Pyrroloquinoline quinone (PQQ)
Featured
|
Pyrroloquinoline quinone (PQQ) is used as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). |
|
| DC20521 |
Pyrrophenone |
Pyrrophenone is a potent cPLA2α inhibitor with enzyme IC50 of 4.2 nM. |
|
| DC22197 |
PZ09(PKC-9)
Featured
|
PZ09 (PKC-zeta inhibitor 9, PKC-ζ inhibitor PZ9) is a potent, isoform selective PKC-zeta (PKC-ζ) inhibitor with IC50 of 5.18 nM, displays excellent selectivity (>200-fold) over other PKC isoforms with exception of PKC-i (10-fold). PZ09 also shows high selectivity for CDK-2 (>200-fold), as well as a broader range of other kinases (<50% inhibition at 10 uM). PZ09 is a small-molecule inhibitor, the first tool to successfully interrogate aPKC signaling in cells. |
|
| DC12548 |
PZ-2891
Featured
|
PZ-2891 is a specific, allosteric, BBB-permeable, orally active Pantothenate kinase (PANK) modulator, acting as both an orthosteric inhibitor (IC50=1.3 nM, hPANK3) and an allosteric activator of PANK3 activity in the presence of acetyl-CoA in biochemical |
|
| DC22203 |
Q151 |
Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (MtbIMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity. |
|
