DC33375 |
Nevirapine-d3 |
Nevirapine-d3 is deuterized nevirapine, reducing P450 metabolite formation, impacting on phase II metabolism and hepatocyte protein expression. |
|
DC33376 |
MS4 |
MS4 is a novel glucocorticoid receptor (GR) agonist with anti-inflammatory activity and displaying reduced impact on islets. |
|
DC33377 |
Pramiverin HCl |
Pramiverin HCl is a bioactive chemical. |
|
DC33378 |
Acepromazine maleate |
Acepromazine maleate, also known as Sch-10649, is a dopamine D1/2 receptor and 5-HT1A/2A receptor antagonist used to prevent nausea and induce sedation.
Acepromazine maleate is discontinued. |
|
DC33379 |
2-Aminopropanol |
L-Alaninol , also known as 2-Aminopropanol, is an amino acid derivative that inhibits melanoma proliferation and increases cytrochrome C reductase and tau-glutamyl transpeptidase. |
|
DC33380 |
Alloxan Monohydrate |
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells. |
|
DC33381 |
Alternariol |
Alternariol is a mycotoxin, topoisomerase I and II inhibitor and potential ER agonist found in Alternaria. |
|
DC33382 |
Alyssin |
Alyssin is a sulforaphane homolog and antioxidant. It induces phase II enzymes and increases Nrf2 levels in adenocarcinoma cells. It is has been shown to decrease the metabolism of polycyclic aromatic hydrocarbons, supressing the risk of carcinogenesis in vitro. |
|
DC33383 |
BIMI-1803 |
Amastatin HCl is an aminopeptidase inhibitor that also induces vasoconstriction. |
|
DC33385 |
Amisulpride HCl |
Amisulpride is an antagonist 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth. |
|
DC33386 |
Amitraz |
Amitraz, also known as Mitaban and Taktic, is an alpha-adrenergic receptor agonist and MAO inhibitor used as an insecticide in prevention of flea and tick infections. It prevents prostaglandin synthesis and may inhibit beta-cell insulin release. |
|
DC33388 |
Amphotericin B
Featured
|
Amphotericin B binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1-beta, TNF-alpha, BDNF and GDNF and protects against prion-induced neurodegeneration. |
|
DC33389 |
Amcill |
Ampicillin Trihydrate is a transpeptidase inhibitor that prevents bacterial cell wall formation. It is effective against gram negative and gram positive bacteria. |
|
DC33390 |
Amprol |
Amprolium HCl is coccidiostat and thiamine transporter inhibitor. It inhibits thiamine transporters in species of Eimera, preventing carbohydrate synthesis. |
|
DC33391 |
BB-NC-0036 |
Anabasine HCl is used as an insecticide and as a clinical biomarker for tobacco smoke exposure. It is also a depolarizing NMJ blocker, nAChr antagonist, aromatase inhibitor, and teratogen found in species of Nicotiana. |
|
DC33392 |
6-Hydroxy hyoscyamine |
Anisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. |
|
DC33393 |
BDBM32804 |
Antipain HCl is a protease inhibitor found in Actinomycetes. |
|
DC33395 |
Arvanil
Featured
|
Arvanil is a CB1 and TRPV1 agonist. It increases lung tidal volume, diaphragm activity, mean arterial blood pressure and inhibits lymphocyte proliferation. |
|
DC33396 |
Atropinol |
Atropine is a mAChR antagonist found in Solanaceae used to initiate mydriasis. It decreases thermal pain, inhibits histamine-induced increases in thromboxane A2, and acts as a positive inotrope. |
|
DC33397 |
Azitro |
Azithromycin dihydrate is a protein translation inhibitor used for it's antibacterial properties. It is also known to inhibit the epithelila-to-mesenchymal transition and suppresses LPS-stimulated production of pro-inflammatory cytokines in macrophages. |
|
DC33398 |
O(6)-Benzylguanine
Featured
|
O(6)-Benzylguanine is an MGMT inhibitor that prevents the repair of DNA damage induced by chemotherapeutics. It allows apoptosis and other mechanisms of cell death to occur. |
|
DC33399 |
Berteroin |
Berteroin is an erucin homolog and potential antioxidant. It is present in cruciferous vegetables, including Chinese cabbage, rucola salad leaves, and mustard oil. It decreases expression of androgen receptors in prostate cancer cells. It also decreases the release of pro-inflammatory cytokines in LPS-stimulated macrophages. |
|
DC33400 |
Bestatin HCl |
Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells. |
|
DC33401 |
L-Biopterin |
Biopterin is an endogenous pterin coenzyme required for production of neutrotransmitters and release of NO |
|
DC33403 |
AH 250 |
Bupivacaine is a BK/SK, Kv1, Kv3, TASK-2 K Channel and voltage-gated Na channel blocker used as an anesthetic. It maybe neurotoxic at high does, inducing apoptosis in neuroblastoma cells. |
|
DC33404 |
AC1NQY7L |
Butein is found in Rhuteic verniciflua and Butea monosperma. It induces cell cycle arrest and apoptosis in lung cancer cells, inhibits vessel spouting from aortic rings, and prevents hepatic stellate cell activation. |
|
DC33405 |
Carulomycin A |
Cerulomycin A is a toxin that inhibits growth of Entamoeba. It may prevent proliferation of cancer cells, and suppresses immune responses. |
|
DC33406 |
Aldadiene |
Canrenone is a metabolite of spironolactone, Na/K ATPase partial agonist and aldosterone and androgen receptor antagonist used as a diuretic. |
|
DC33407 |
Carbadoxum |
Carbadox is a livestock anitbiotic and growth promoter. It is particularly effective in treating swine dysentery and enteritis. However, its use has been prohibited in the UK following reports of carcinogenicity and mutagenicity. |
|
DC33409 |
Ceclor |
Cefaclor monohydrate is a penicillin binding protein inhibitor that prevents peptidoglycan synthesis and bacterial cell wall formation. It also enhances phagocytosis, bacterial activity of granulocytes and macrophages, and slows gastric emptying and intestinal transit. |
|