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Zidesamtinib

  Cat. No.:  DC72794   Featured
Chemical Structure
2739829-00-4
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More than 5000 active chemicals with high quality for research!
Field of application
Zidesamtinib (NVL-520) is a potent, selective, orally active and brain-penetrant inhibitor of diverse ROS1 fusions and resistance mutations, with IC50s of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and spares TRK inhibition. Zidesamtinib can be used for the research of cancer.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2739829-00-4
Chemical Name: Zidesamtinib
Synonyms: 7H-8,12-Metheno-4H-pyrazolo[3,4-h]-1,2,3-triazolo[4,5-k][2,5]benzoxaazacyclotetradecin-11-amine, 7-ethyl-16-fluoro-2,14-dihydro-2,14-dimethyl-, (14R)-;Zidesamtinib
SMILES: C(N1N=CC2CC3=NN(N=C3C3=CC=C(C=C3[C@H](OC3=C(N=CC(=C3)C=21)N)C)F)C)C
Formula: C22H22FN7O
M.Wt: 419.454786777496
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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