Cat. No. | Product name | CAS No. |
DC33566 |
Alizarin Complexone
Alizarin Complexone, also known as Alizarin-3-methyliminodiacetic acid, is use blue dye for biological study. |
3952-78-1 |
DC33568 |
J9
J9 is a Glucocorticoid resistance inhibitor. J9 Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL). |
947018-15-7 |
DC33569 |
MreB Perturbing Compound A22
A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant. A22 inhibition of MreB disrupts the bacterial actin cytoskeleton, which can cause an increase in cell permeability and altered transport. |
22816-60-0 |
DC33570 |
TCS-2002
TCS-2002 is a Potent inhibitor of GSK-3β (IC50 = 35 nM). Oral adminstration inhibits cold water stress-induced tau hyperphosphorylation in the mouse brain. |
1005201-24-0 |
DC33571 |
CAY10566
Featured
CAY10566 is a potent and selective inhibitor of SCD1 that demonstrates IC50 values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. |
944808-88-2 |
DC33573 |
IMB-808
IMB-808 is a potent liver X receptor α and β (LXRα/β) partial dual agonist that promotes expression of genes related to reverse cholesterol transport (including ABCA1 and ABCG1). |
870768-70-0 |
DC33575 |
TOP1362
TOP1362 is a Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. TOP1362 strongly inhibited the kinase targets p38α, Syk, Src, and Lck, blocked the rise in p38α expression in hyperosmolar Chang cells, and potently reduced inflammatory cytokine release in cellular models of innate and adaptive immunities. In the EIU model, TOP1362 dose-dependently attenuated the LPS-induced rise in inflammatory cell infiltration and ocular cytokine levels with efficacy comparable to that of dexamethasone. |
1630203-25-6 |
DC33576 |
LJ570
Featured
LJ570 is the first PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. LJ570 is a potent partial agonist of both PPARα and γ subtypes. LJ570 inhibited the Cdk5-mediated phosphorylation of PPARγ at serine 273 that is currently considered the mechanism by which some PPARγ partial agonists exert antidiabetic effects similar to thiazolidinediones, without showing their typical side effects. LJ570 may be useful for treatment of dyslipidemic type 2 diabetes. |
2252488-69-8 |
DC33577 |
RG7834 R-isomer
RG7834 R-isomer, also known as RO0321, is an enantiomer of RG7834 and a negative control for RG7834. RG7834 R-isomer has R-configuration with CAS#2072057-18-0. RG7834 is a novel oral HBV viral gene expression inhibitor that blocks viral antigen and virion production. RG7834 is highly selective for HBV, and has a unique antiviral profile that is clearly differentiated from nucleos(t)ide analogues. |
2072057-18-0 |
DC33579 |
RO2959 Hydrochloride
Featured
RO2959 is a novel, potent and selective CRAC current inhibitor. RO2959 completely inhibited cytokine production as well as T cell proliferation mediated by TCR stimulation or MLR (mixed lymphocyte reaction). RO2959 potently blocked TCR triggered gene expression and T cell functional pathways similar to CsA and another calcineurin inhibitor FK506. |
1219927-22-6 |
DC33580 |
DODMA
Featured
DODMA, also known as MBN 305A is a a cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery |
104162-47-2 |
DC33581 |
Decaethylene glycol
Decaethylene glycol is a polyethylene glycol derivative, can be used as a |
5579-66-8 |
DC33584 |
ARN14974
Featured
ARN14974 is a benzoxazolone carboxamide inhibitor of acid ceramidase (IC50 = 79 nM). |
1644158-57-5 |
DC33585 |
5WKS
5WKS, also known as ZINC97756584, is a biochemical |
1350752-07-6 |
DC33586 |
RGX-104 free form
Featured
RGX-104, also known as SB 742881, is a liver X receptor beta agonist with potential immunomodulating and antineoplastic activities. Upon oral administration, RGX-104 selectively targets and binds to LXRbeta, thereby activating LXRbeta-mediated signaling, leading to the transcription of certain tumor suppressor genes and the downregulation of certain tumor promoter genes. This particularly activates the expression of apolipoprotein E (ApoE), a tumor suppressor protein, in tumor cells and certain immune cells. This activates the innate immune system, resulting in depletion of immunosuppressive myeloid-derived suppressor cells (MDSCs), tumor cells and endothelial cells in the tumor microenvironment. This reverses immune evasion, enhances anti-tumor immune responses and inhibits proliferation of tumor cells. |
610318-54-2 |
DC33587 |
cvxIAA
cvxIAA is an orthogonal auxin-TIR1 receptor pair. cvxIAA triggers auxin signaling without interfering with endogenous auxin or TIR1/AFBs. cvxIAA hijacked the downstream auxin signaling in vivo both at the transcriptomic level and in specific developmental contexts, only in the presence of a complementary, concave TIR1 (ccvTIR1) receptor. cvxIAA-ccvTIR1 system serves as a powerful tool for solving outstanding questions in auxin biology and for precise manipulation of auxin-mediated processes as a controllable switch. |
2127037-35-6 |
DC33588 |
Bentranil
Bentranil is pesticide agent. |
1022-46-4 |
DC33589 |
Spermine free base
Spermine, a polycationic biogenic polyamine derived from spermidine, may be used in a wide variety of biological applications as a supplement or regulatory agent.Used as co-matrix with DHB for MALDI-MS of sialylated glycans in negative ion mode. |
71-44-3 |
DC33590 |
Spermine HCl
Spermine, a polycationic biogenic polyamine derived from spermidine, may be used in a wide variety of biological applications as a supplement or regulatory agent.Used as co-matrix with DHB for MALDI-MS of sialylated glycans in negative ion mode. |
306-67-2 |
DC33591 |
GSK269962 HCl
GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively. GSK 269962 could reverse corticosterone-induced depressive-like behaviour and changes in cystometric parameters associated with detrusor overactivity, as well as undo the alterations of several biomarkers related to both disorders (i.e., pro-inflammatory/anti-inflammatory cytokines and neurotrophins) in serum, urinary bladder, and different brain structures. |
2095432-71-4 |
DC33594 |
GK187
GK187 is a potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2. |
1071001-50-7 |
DC33595 |
ARRY-371797
ARRY-797, also known as ARRY-371797, is a potent and selective p38α inhibitor (p38 mitogen-activated protein kinase inhibitor). ARRY-371797 Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells. |
1036404-17-7 |
DC33596 |
PTI-428
PTI-428 is a type of CFTR modulator known as an amplifier, which acts to increase the amount of CFTR proteins a cell makes. |
1953130-87-4 |
DC33597 |
BIBF0775
Featured
BIBF0775 is an inhibitor of the transforming growth factor β receptor I (TGFβRI). X-ray structure analysis showed that BIBF0775 soaked into the kinase domain of TGFβRI. |
334951-90-5 |
DC33598 |
GSK-805
Featured
GSK805, also known as ROR gamma-t-IN-1, is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA binding. |
1426802-50-7 |
DC33599 |
LYN-1604 HCl
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. LYN-1604 could induce cell death, associated with autophagy by the ULK complex (ULK1-mATG13-FIP200-ATG101) in MDA-MB-231 cells. To further explore LYN-1604-induced autophagic mechanisms, we found some potential ULK1 interactors, such as ATF3, RAD21, and caspase3, by performing comparative microarray analysis. LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. |
2216753-86-3 |
DC33600 |
E3 ligase Ligand 5
Featured
E3L-4133, also known as E3 ligase Ligand 5, is an E3 ligase Ligand that can be used in PROTAC (proteolysis targeting chimera) technology to engage an E3 ubiquitin ligase. PROTAC is a two-headed molecule capable of removing specific unwanted proteins. E3L-4133 has CAS#1264754-13-3. The last 4 digits was used for name. |
1264754-13-3 |
DC33601 |
PhTX-433
PhTX-433, also known as Philanthotoxin 433, is a polyamine-containing toxin, which blocks NMDA-gated ion channels; originally isolated from the venom of the wasp Philanthus triangulum. |
276684-27-6 |
DC33602 |
QBS(CU242)
Featured
QBS(CU-242) or 2-Amino-N-quinolin-8-yl-benzenesulfonamide, is an Inhibitor of cell cycle at G2 phase; apoptosis inducer. NUN82647 has CAS#16082-64-7, and inchi key: NIOOKXAMJQVDGB-UHFFFAOYSA-N. According to Hodoodo Chemical Nomenclature, It is named: NUN-82647. |
16082-64-7 |
DC33603 |
CK1-IN-1
Featured
CK1-IN-1, is a casein kinase 1 (CK1) inhibitor. PUN51207 was reported in patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively. |
1784751-20-7 |
DC33605 |
Gadobutrol Monohydrate
Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease. Similarly, gadobutrol is also used in contrast-enhanced magnetic resonance angiography (CE-MRA) for the diagnosis of stroke, detection of tumor perfusion, and presence of focal cerebral ischemia. |
198637-52-4 |
DC33606 |
CTX-0124143
Featured
CTX-012414 is a KAT6A inhibitor with IC50 value of 0.49 μM and KD value of 0.38 -M. |
423731-64-0 |
DC33607 |
Myristoyl Pentapeptide-17
Featured
Myristoyl Pentapeptide-17 is small peptide. Myristoyl Pentapeptide-17 promotes the delivery of key ingredients for quicker lash growth, thus stimulates the hair growth at the follicle. Myristoyl Pentapeptide-17 effectively promotes the growth of eyelashes. It lengthens and thickens the eyelashes, fortifies the hair and noticeably intensifies eye expression. |
959610-30-1 |
DC33608 |
GAT228
GAT228 is an allosteric agonist of cannabinoid receptor 1 (CB1), the R-(+)-enantiomer of the CB1 positive allosteric modulator (PAM) GAT229, and a component of the racemic mixture GAT211, which acts as both an agonist and PAM. |
1446648-15-2 |
DC33609 |
GAT229
GAT229 is a positive allosteric modulator of cannabinoid receptor 1 (CB1) and the S-(-) enantiomer of the CB1 modulator GAT211. It does not activate the receptor on its own but enhances the binding and activity of CB agonists. |
889860-85-9 |
DC33611 |
PSMA-617 Linker
Featured
Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is composed of a linker and Glutamate-urea-Lysine, can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine is is the selective pharmacophore to bind to prostate specific membrane antigen (PSMA). |
1703768-74-4 |
DC33612 |
PFN62958
PFN62958 is a useful peptide linker for synthesis of PSMA-617 (vipivotide tetraxetan), which is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA-617 originally was developed at the German Cancer Research Center and the Heidelberg University Hospital. ABX held the exclusive license to bring the treatment, which targets prostate-specific membrane antigen (PSMA), through early clinical development. is a tris(tert-butyl)-protected JUN68744 derivative. PFN62958 has CAS#2230662-95-8. According to Hodoodo Chemical Nomenclature, its name is PFN62958 |
2230662-95-8 |
DC33613 |
INT-777
Featured
INT-777 is a semisynthetic bile acid that acts as an agonist of TGR5 (EC50 = 0.82 μM). INT-777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis. |
1199796-29-6 |
DC33614 |
KL-1333(NQO1 activator 1)
Featured
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL-1333 Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. |
1800405-30-4 |
DC33615 |
BAM8-22
BAM8-22 is a Endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM); first isolated from bovine adrenal medulla. |
412961-36-5 |
DC33616 |
CPFX4158
CPFX4158 is a mannose deriviative, and is potentially useful in transgenic humanized-?CEACAM6 mouse as antibacterial agent. |
1804962-84-2 |
DC33617 |
TP-2857
TP-2857 is antimicrobial agent. |
1575491-01-8 |
DC33618 |
TBAJ-587
Featured
TBAJ-587 is a potent anti-tuberculosis agent. TBAJ-587 inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assay, respectively. BAJ-587 has more potent activity against M. tuberculosis and better efficacy in animal models of TB. |
2252316-16-6 |
DC33619 |
LSP-249
LSP-249 is a plasma kallikrein inhibitor for treatment of angioedema. |
1801253-04-2 |
DC33620 |
DAAO inhibitor-1
KUN50259, also known as DAAO inhibitor-1, is a potent D-amino acid oxidase (DAAO) inhibitor with an IC50 of 0.12 μM. DAAO inhibitor-1 has CAS#2065250-25-9. It is named as KUN50259 according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature). |
2065250-25-9 |
DC33621 |
RP-54745
RP-54745 is an Inhibitor of macrophage stimulation and interleukin-1 production. RP 54745 might influence certain cells and cytokines implicated in the regulation of the immune system, the disfunctioning of which can lead to inflammatory disorders or autoimmune pathologies. RP-54745 is a very attractive antirheumatic compound and a potentially effective treatment in pathologies where IL-1 production is exacerbated. |
135330-08-4 |
DC33622 |
CG347B
Featured
CG347B is a biochemical. |
1598426-03-9 |
DC33623 |
CPFX2090
CPFX2090 is a biochemical. |
1429439-25-7 |
DC33625 |
ITMN 4077
ITMN 4077 is a biochemical |
790305-05-4 |
DC33626 |
CPFX1302
CPFX1302 is a biochemical |
|
DC33627 |
SEP-0371845
SEP-0371845 is a biochemical |
1516896-06-2 |
DC33628 |
TP-4748
TP-4748 is a biochemical. |
1150114-62-7 |
DC33629 |
TP748
TP748 is a bioactive chemical. |
951698-15-0 |
DC33630 |
ZN2007-RM1
ZN2007-RM1 is a bioactive chemical. |
|
DC33632 |
CAY10594
Featured
CAY10594 is a potent phospholipase D2 inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis. |
1130067-34-3 |
DC33634 |
DOPE
Featured
DOPE, also known as 1,2-Dioleoyl-sn-glycero-3-PE or 1,2-DOPE, is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery. |
4004-05-1 |
DC33635 |
DODAP
Featured
DODAP, also known as 1,2-Dioleoyl-3-dimethylammonium-propane, is a cationic lipid. It has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery. |
127512-29-2 |
DC33636 |
DOTAP
Featured
DOTAP, also known as 1,2-Dioleoyl-3-trimethylammoniumpropane, is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in gene delivery vectors for gene ther |
132172-61-3 |
DC33637 |
RU-SKI43 HCl
RU-SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI-43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR. |
1782573-67-4 |
DC33638 |
CY5.5-COOH
CY5.5 carboxylic acid, also known as Cyanine5.5 carboxylic acid, is a Far-red emitting fluorescent dye with Ex/Em wavelength 673nm/707nm. CY5.5 carboxylic acid can be considered non-reactive for most applications and used as a control or reference sample, and for instrument calibration. |
1144107-80-1 |
DC33640 |
DOPC
Featured
DOPC, also known as 18:1 (Δ9-Cis) PC, is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions. It is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. |
4235-95-4 |
DC33641 |
PSB-12054
PSB-12054 is a potent P2X4 receptor inhibitor. PSB-12054 has IC(50) of 0.189 μM and good selectivity versus the other human P2X receptor subtypes. |
1407632-07-8 |
DC33643 |
ARC39
ARC39 is acid sphingomyelinase inhibitor (IC50 =20 nM). |
15049-89-5 |
DC33644 |
MC2050 HCl
MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells. |
1301757-19-6 |
DC33645 |
TBK1/IKKε-IN-5
Featured
QUN97653, also known as TBK1/IKKε-IN-5, is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively. QUN97653 was first reported in patent WO 2016049211. It has CAS#1893397-65-3 without code name. For the convenience of scientific communication, we temporally name it as QUN97653, which was based on Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature). |
1893397-65-3 |
DC33647 |
CM-4620
Featured
CM-4620 is a calcium-release activated calcium-channel (CRAC channel) inhibitor, with IC50s of 119 nM, 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively. |
1713240-67-5 |
DC33648 |
Hexakis(p-bromophenoxy)cyclotriphosphazene
Featured
LUN76721 has CAS#4376-72-1, is a cyclophosphazene and a useful chemical reagent. Cyclophosphazenes have been studied among others as flame retardant additives, high temperature fluids, clathrates, photostabilizers, or antioxidants in organic polymers. Cyclophosphazenes have also been used as phase transfer catalysts, as polypodants and cryptands. Cyclophosphazenes have also been successfully used as biologically active agents. Moreover cyclotriphosphazenes, were used for polymer functionalization and synthesis, as pendant groups or monomers for polyphosphazene synthesis, especially those bearing six chlorine atoms or phenoxy groups. |
4376-72-1 |
DC33649 |
Boc-Val-Cit-PAB
Featured
Boc-Val-Cit-PAB is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group. |
870487-09-5 |
DC33650 |
IUN76750
Featured
UTL-5g is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity. It lowers elevated levels of AST, ALT, creatinine, BUN, and TNF-α, increases the reduced platelet count in mice, and acts as a novel chemo- and radioprotective agent. |
1690176-75-0 |
DC33651 |
ML188
Featured
ML188 is a Potent Noncovalent Small Molecule Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease. The X-ray structure of SARS-CoV 3CLpro bound with ML188 was instrumental in guiding subsequent rounds of chemistry optimiz |
1417700-13-0 |
DC33652 |
LY-3381916
Featured
LY-3381916, also known as IDO1-IN-5, is a potent, selective and brain penetrated DO1 inhibitor. LY3381916 specifically targets and binds to IDO1, a cytosolic enzyme responsible for the oxidation of the amino acid tryptophan into the immunosuppressive metabolite kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, LY3381916 restores and promotes the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, and T lymphocytes, and causes a reduction in tumor-associated regulatory T cells (Tregs). |
2166616-75-5 |
DC33653 |
ML417
Featured
ML417 is a Highly Selective D3 Dopamine Receptor Agonist. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein activation, and ERK1/2 phosphorylation (pERK) while lacking activity at other dopamine receptors. Screening of ML417 against multiple G protein-coupled receptors revealed exceptional global selectivity. Molecular modeling suggests that ML417 interacts with the D3R in a unique manner, possibly explaining its remarkable selectivity. ML417 was also found to protect against neurodegeneration of dopaminergic neurons derived from iPSCs. |
1386162-69-1 |
DC33654 |
Fentin
Fentin is an organotin compound (OTC) widely used as an agricultural fungicide and miticide. |
76-87-9 |
DC33655 |
Methyldymron
Methyldymron is a bioactive chemical. |
42609-73-4 |
DC33656 |
Noreximide
Noreximide is a sedative. |
3647-74-3 |
DC33657 |
DNOC
DNOC is an agricultural chemical. |
534-52-1 |
DC33658 |
EINECS 206-113-3
Robinin is a flavone glycoside based on kaempferol. |
301-19-9 |
DC33659 |
Arsicodile
Sodium cacodylate is an arsenical that has been used as a dermatologic agent and as an herbicide. |
124-65-2 |
DC33660 |
2-Naphthalenecarboxamide
C.I. 37530 is a color developer. |
135-62-6 |
DC33661 |
2-Naphthanilide
3-Hydroxy-3'-nitro-2-naphthanilide is a bioactive chemical. |
135-65-9 |
DC33662 |
3-Cyclohexene-1-methanol
Levomenol is found in fats and oils. |
23089-26-1 |
DC33663 |
Antibiotic BB-K 8
Amikacin is an aminoglycoside antibiotic derived from kanamycin A. Like other aminoglycosides, amikacin binds to bacterial ribosomes and disrupts translation.1 However, the specific binding sites differ between different aminoglycoside antibiotics, as do the mechanisms of resistance. Amikacin is effective against Gram-negative and Gram-positive bacteria. |
37517-28-5 |
DC33664 |
Bekanamycin sulfate
Bekanamycin sulfate is a bioactive chemical. |
29701-07-3 |
DC33665 |
Bismuth oxide salicylate
Bismuth subsalicylate is the active ingredient of Pepto-Bismol and in Kaopectate. It is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea and other temporary discomforts of the stomach. |
14882-18-9 |
DC33666 |
Acarie M
Mancozeb is an agricultural ethylene bisdithiocarbamate fungicide. |
|
DC33667 |
GS 14259
Terbumeton is an herbicide. |
33693-04-8 |
DC33668 |
Arilat
Carbaryl is a carbamate insecticide, commonly used to control aphids, fire ants, fleas, ticks, spiders, and many other outdoor pests. |
63-25-2 |
DC33669 |
EC 201-304-8
Dimethyl imidazolidinone is a cyclic urea used as a high-boiling polar aprotic solvent. |
80-73-9 |
DC33670 |
Metham sodium
Metam-sodium is an organosulfur compound, used as a soil fumigant, pesticide, herbicide, and fungicide. |
137-42-8 |
DC33671 |
Fenylisokyanat
Phenyl isocyanate is a aromatic monoisocyanate and potent inducer of both cellular and humoral immune responses. |
103-71-9 |
DC33672 |
Carbicron
Dicrotophos is a systemic insecticide with a large range of applications. |
141-66-2 |
DC33673 |
Carbohydrazide
Carbohydrazide is a high performance oxygen scavenger which can be used in all types of boilers. |
497-18-7 |
DC33674 |
Tandex
Karbutilate is a carbamate herbicide. |
4849-32-5 |
DC33675 |
Anacardone
Nikethamide is a central nervous system stimulant. It is a clear light yellow viscous liquid or crystalline solid and has a slightly bitter taste followed by a faint sensation of the warmth. |
59-26-7 |
DC33676 |
Lirobetarex
Monuron is an herbicide, made up of white crystalline solid or white powder with a slight odor. |
150-68-5 |
DC33677 |
Karphos
Isoxathion is an organothiophosphate insecticide. |
18854-01-8 |
DC33678 |
Caldan
Cartap hydrochloride is an insecticidal derivative that is used to control chewing and sucking insects on many crops. |
15263-52-2 |
DC33679 |
Kasutop Dust
EPN is an organothiophosphorus cholinesterase inhibitor that is used as an insecticide and as a acaricide. |
2104-64-5 |
DC33680 |
HSDB 3165
Potassium gluconate is a mineral supplement used to treat or prevent low amounts of potassium in the blood. |
299-27-4 |
DC33681 |
CCRIS 1514
Kaurenoic acid is a bioactive chemical. |
6730-83-2 |
DC33682 |
Gummiferin
Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT). |
33286-30-5 |
DC33683 |
Steviolmonoside
Glucosilsteviol is a sophorose moiety of steviol replaced by glucose. |
60129-60-4 |
DC33684 |
Delnatex
Dioxation is an organophosphate pesticide. It is used as an insecticide on livestock and as an acaricide on citrus fruits, deciduous fruits and nuts. |
78-34-2 |
DC33685 |
BRN 2219123
Methasulfocarb is a fungicide, bactericide, and wood preservative. |
66952-49-6 |
DC33686 |
Congo red
Congo red is an acid dye used in testing for hydrochloric acid in gastric contents. It is also used histologically to test for AMYLOIDOSIS. |
573-58-0 |
DC33687 |
Brilliant acid flavine 10J
Brilliant sulfaflavine is used as fluorescent tracers to study the application rate of foliar fungicides when applied to soybeans for the control of rust. |
2391-30-2 |
DC33688 |
Kayametone
Methoxyphenone is an environmentally sound herbicides. |
41295-28-7 |
DC33689 |
Vinyltriethoxysilane
Vinyltriethoxysilane is an aqueous adhesive for affixing sections to glass slides when hydrolyzed. |
78-08-0 |
DC33690 |
Flutoprazepam
Flutoprazepam is a benzodiazepine derivative extensively biotransformed by hepatic microsomal oxidation. This drug is unschedule in the USA but classified as a Schedule IV controlled substance in Canada. |
25967-29-7 |
DC33691 |
Fenhexamid
Fenhexamid is an antifungal agent (pesticides) used for agriculture, and is present at measurable amounts in fruits and vegetables. |
126833-17-8 |
DC33692 |
Acid yellow 1
Acid yellow 1 is a dye for amino acid and peptide precipitations. |
846-70-8 |
DC33693 |
Fenothiocarb
Fenothiocarb is a pesticide. |
62850-32-2 |
DC33694 |
Risocaine
Risocaine is a local anesthetic. |
|
DC33695 |
Tetroquinone
Tetroquinone is used to remove warts, calluses and other lesions in which the epidermis produces excess skin. |
319-89-1 |
DC33696 |
Astemizole
Featured
Astemizole is a histamine H1-receptor antagonist. Astemizole competitively binds to histamine H1-receptor sites in the gastrointestinal tract, uterus, blood vessels, and bronchial muscle. This suppresses the formation of edema and pruritus caused by histamine. Astemizole is structurally similar to terfenadine and haloperidol; it has anticholinergic and antipruritic effects. |
68844-77-9 |
DC33697 |
Anilazine
Anilazine is a pesticide used on crops. It comes under the category of triazine fungicides. |
101-05-3 |
DC33698 |
Phosmet
Phosmet is an organothiophosphorus insecticide that has been used to control pig mange. |
732-11-6 |
DC33699 |
K-756
Featured
K-756 is a a selective Wnt/β-catenin pathway inhibitor. K-756 is also a tankyrase (TNKS) inhibitor. K-756 binds to the induced pocket of TNKS and inhibits its enzyme activity. could be a leading compound in the development of anticancer agents. |
130017-40-2 |
DC33700 |
K6PC-5
K6PC-5 is a sphingosine kinase 1 (SphK1) activator. |
756875-51-1 |
DC33701 |
Oxyphenonium bromide
Oxyphenonium bromide is a quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. |
|
DC33702 |
2,2'-Bipyridine
2,2'-Bipyridine is a universal activator of miRNAs, which modulated miRNA expression levels by promoting the processing of miRNA precursors. |
366-18-7 |
DC33706 |
Valilactone
Valilactone is a fatty acid synthase inhibitor produced by a cultured strain of soil actinomycetes. Fatty acid synthase (FAS) is necessary for growth and survival of tumor cells and is a promising drug target for oncology. |
113276-96-3 |
DC33707 |
Valinomycin
Featured
Valinomycin is an cyclododecadepsipeptide ionophore antibiotic that acts as an insecticide and nematocide. |
2001-95-8 |
DC33708 |
Valnemulin hydrochlordie
Valnemulin is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia. It is also used for the prevention of intestinal infections of swine. Valnemulin has been observed to induce a rapid reduction of clinical symptoms of Mycoplasma bovis infection, and eliminate M. bovis from the lungs of calves. |
133868-46-9 |
DC33711 |
Phenmedipham
Phenmedipham is a herbicide, especially in the growing of sugar beet and strawberries. |
13684-63-4 |
DC33712 |
Desoxycortone
Desoxycortone is a steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE. |
64-85-7 |
DC33713 |
Captafol
Captafol is a fungicide. It is used to control almost all fungal diseases of plants except powdery mildews. |
|
DC33714 |
Sodium salicylate
Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized by hydrolysis of methyl salicylate (extracted from wintergreen plants or the bark of sweet birch tree) with an excess of sodium hydroxide and heating it under reflux. |
54-21-7 |
DC33715 |
Kessane
Kessane is a sesquiterpenoid oxide isolated from Japanese valerians. It has been elucidated to have the stereostructure I on the basis of its spectroscopic and chemical studies and derivation from 2-epi-α-kessyl alcohol. |
3321-66-2 |
DC33716 |
Acetyl ketene
Diketene, also known as Acetyl ketene, is used as a chemical intermediate for acetoacetic esters and acetoacetanilides, dyes, pharmaceuticals, food preservatives, and insecticides. |
|
DC33717 |
Ketopioglitazone
Ketopioglitazone is an active metabolite of pioglitazone and is found in human plasma. |
|
DC33718 |
Ketoisophorone
Ketoisophorone is a prochiral compound and a major component of saffron spice. It is a cyclic olefin. |
|
DC33719 |
Keto-pantoyllactone
Keto-pantoyllactone is assayed by the spectrophotometric measurement of ketopantoyl lactone-dependent oxidation of nicotinamide adenine dinucleotide phosphate. |
|
DC33720 |
Keto-itraconazole
Keto-itraconazole is a metabolite of Itraconazole. |
|
DC33721 |
Rhodblock 3
Rhodblock 3 is a small molecule and potent inhibitor of the Rho pathway. |
|
DC33722 |
L-742001
L-742001 Hydrochloride is an inhibitor of RNA polymerase. |
|
DC33723 |
Clorophene
Clorophene is an antimicrobial and is found in hospitals and restaurants. |
|
DC33724 |
NQN-1
NQN-1 is a histone deacetylases-6 (HDAC6) inhibitor and nuclear factor-κB (NF-κB) activation blocker. |
|
DC33725 |
NCT-14b
NCT-14b is a selective HDAC6 inhibitor. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells. |
|
DC33726 |
CHD-5
CHD-5 is selective aryl hydrocarbon receptor (AhR) antagonist. |
|
DC33727 |
VK3-OCH3
VK3-OCH3 is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue. |
|
DC33728 |
CID-5951923
CID-5951923 is a Kruppel-like factor 5 (KLF5) expression inhibitor. When tested in the NCI-60 panel of human cancer cell lines, compound CID 5951923 was selectively active against colon cancer cells. |
|
DC33729 |
GZ-793A
GZ-793A inhibits dopamine uptake at the vesicular monoamine transporter-2 (VMAT2. A lobelane analog, GZ-793A interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine. |
|
DC33730 |
FAUC-365
Featured
FAUC 365 is a highly dopamine D3 receptor-selective antagonist with Ki values of 0.5 nM, 340, 2600, and 3600 nM at D3, D4.4, D2short, and D2Long receptors, respectively. FAUC 365 can be used for the research of schizophrenia, and Parkinson's disease. |
474432-66-1 |
DC33732 |
VUF8430 dihydrobromide
VUF8430 dihydrobromide is a histamine H4 receptor full agonist. |
|
DC33733 |
Compound E
Compound E is a cell-permeable, potent, selective inhibitor of ?-secretase and Notch processing. |
|
DC33734 |
NNK
Featured
NNK is a procarcinogen, a major tobacco-specific toxicant that inhibits the expression of lysyl oxidase, a tumor suppressor. |
64091-91-4 |
DC33735 |
Benziodarone
Benziodarone is a vasodilator. Results suggest that benziodarone has an amiodarone-like action. |
|
DC33736 |
2-Acetylfuran
2-Acetylfuran is a uricosuric drug. It is used to effectively to control hyperuricemia in renal transplantation |
|
DC33737 |
3-Acetyl-2,5-dimethylfuran
3-Acetyl-2,5-dimethylfuran is a flavouring agent and it has a musty type odor and an nutty type flavor. |
|
DC33738 |
Deiodoamiodarone
Deiodoamiodarone is an intermediate of amiodarone, which is an α/β-adrenergic receptor antagonist and coronary vasodilator. |
|
DC33739 |
4-Hydroxytoremifene
4-Hydroxytoremifene is a selective estrogen receptor modulator toremifene active metabolite. |
|
DC33740 |
Pyoluteorin
Pyoluteorin is an antifungal agent composed of a 4,5-dichlorinated pyrrole group linked to a resorcinol moiety. The pyoluteorin biosynthetic gene cluster in Pseudomonas fluorescens Pf-5 encodes the halogenase PltA, which has been previously demonstrated to perform both chlorinations in vitro. Pyoluteorin protects various plants from diseases caused by soilborne pathogenic fungi. |
|
DC33741 |
p-Phenylpropiophenone
p-Phenylpropiophenone is anticipated to act as an energy sink. |
|
DC33742 |
Quinacetol sulfate
Quinacetol is a fungicide compound useful in organic synthesis. |
|
DC33743 |
2-Hexanone
2-Hexanone ketone is an industrial solvent which causes nervous system degeneration. MBK is an acronym often used to refer to it. It is used as a general solvent and in paints. It dissolves cellulose nitrate, vinyl polymers and copolymers, and natural and synthetic resins. |
|
DC33744 |
Cyclohexylphenylketone
Cyclohexylphenylketone is a Spectrophotometric determination of benzophenone. |
|
DC33745 |
Cyclopropyl methyl ketone
Cyclopropyl methyl ketone was used in the preparation of homoallylic alcohols. |
|
DC33746 |
Dicyclohexyl ketone
Dicyclohexyl ketone is a vulcanization accelerator. It is concluded that the No Observed Adverse Effect Levels (NOAELs) for repeat dose and reproductive/developmental toxicity are 100 mg kg-1 day-1. |
|
DC33747 |
Benzophenone
Benzophenone is a photo initiator in UV-curing applications such as inks, imaging, and clear coatings in the printing industry. Benzophenone prevents ultraviolet (UV) light from damaging scents and colors in products such as perfumes and soaps. |
|
DC33748 |
Methyl ethyl ketone
Methyl ethyl ketone is a liquid solvent used in surface coatings, adhesives, and printing inks. It is found in colorless synthetic resins and smokeless powders and may be irritating to eyes, mucous membranes; it may be toxic in high concentrations. |
|
DC33749 |
Phenyl ethyl ketone
Phenyl ethyl ketone is an aryl ketone. It is a colorless, sweet-smelling liquid that is insoluble in water, but miscible with organic solvents. It is used in the preparation of other compounds. |
|
DC33750 |
1-Pentene-3-one
1-Pentene-3-one is a reactive compound classified as an enone. It is a colorless, flammable, highly toxic liquid with a pungent odor; it is the oxidized product of pentanol. |
|
DC33751 |
1-(4-Pyridinyl)-1-propanone
1-(4-Pyridinyl)-1-propanone is chemical for drug synthesis |
|
DC33752 |
2-Acetylfluorene
2-Acetylfluorene is a product for proteomics research. |
|
DC33753 |
1-Acetylferrocene
1-Acetylferrocene is an organoiron compound with the formula Fe. It consists of ferrocene substituted by an acetyl group on one of the cyclopentadienyl rings. It is an orange, air-stable solid that is soluble in organic solvents. |
|
DC33754 |
2-Nonanone
2-Nonanone is a flavor and fragrance agents. It has a fruity type odor and an cheesy type flavor. |
|
DC33755 |
Octanophenone
Octanophenone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 μm particles columns available for fast UPLC applications. This method is scalable and can be used for isolation impurities in preparative separation. |
|
DC33756 |
3-Acetylindole
3-Acetylindole is a derivative of an indole. The substitution of indole in position 3 with aldehydes and with alkyl groups cause only minor changes in the molecular geometry, however, substantially larger alterations are found in the charge distribution and in the vibrational force constants. |
|
DC33757 |
2-Acetylthiophene
2-Acetylthiophene is a fragrance agent. It has a sulfurous type odor and an onion type flavor. |
|
DC33758 |
2-Acetylnaphthalene
2-Acetylnaphthalene is an anticonvulsant/antimicrobial and a fragrance agent. It has a sulfurous type odor and an onion type flavor. |
|
DC33759 |
Acetophenone
Acetophenone is used for fragrance in soaps and perfumes, as a flavoring agent in foods, and as a solvent for plastics and resins. It is also a flavouring ingredient used in fruit flavours. |
|
DC33760 |
2-Acetyl-5-methylthiophene
2-Acetyl-5-methylthiophene is a constituent of coffee aroma. |
|
DC33761 |
2-Acetylpyrazine
2-Acetylpyrazine is a pyrazine and a ketone. It is a yellow-brown powder at room temperature. |
|
DC33762 |
2-Acetylthiazole
2-Acetylthiazole is used in the preparation of triazolothiazoles, chiral alcohols and in aldol condensation reactions. |
|
DC33763 |
3-Oxo-3-phenylpropene
3-Oxo-3-phenylpropene is an active-site directed irreversible hydroxynitrile lyase inhibitor. Lyase is an FAD-protein. The substrate and competitors (e.g. benzoate) decrease the rate of the inhibitor-mediated deactivation of the enzyme. |
|
DC33764 |
3-Benzoylpyridine
3-Benzoylpyridine is a decomposition product of the soman antidote HGG-12. |
|
DC33765 |
3,3-Dimethyl-2-butanone
Pinacolin is a metabolite of soman. |
|
DC33766 |
Capriphenone
Capriphenone acts as an intermediate for antibacterial, antifungal, antiviral and antituberculous products. |
|
DC33767 |
Perylene Red
Perylene Red is a fluorescent dye molecule. |
|
DC33768 |
Methyl dihydrojasmonate
Methyl dihydrojasmonate is an aroma compound used to prepare hydrogels as delivery systems for the slow release of bioactive carbonyl derivatives. |
|
DC33769 |
Isoprocarb
Isoprocarb is a pesticide metabolite |
|
DC33770 |
Trichlorfon
Trichlorfon is organophosphorous pesticide and among the most commonly used products to treat fish parasites in aquaculture. It is also used in anthelmintic compositions for animals. |
|
DC33771 |
Bitriben
Bitriben is an anthelmintic agent. |
|
DC33772 |
Chromotrope 2B
Chromotrope 2B is a reagent for boric acid and borates. |
|
DC33774 |
Iprodione
Iprodione is a fungicide, bactericide, and wood preservative. |
|
DC33775 |
Kifunensine
Kifunensine is potent and selective inhibitor of class I α-mannosidases and may serve as a key inhibitor of glycoprotein biosynthesis. Its inhibitory action leads to the high mannose glycoproteins in cell culture. |
|
DC33776 |
Benthiavalicarb isopropyl
Benthiavalicarb isopropyl is a fungicide, specifically targeting blight and downy mildew. |
|
DC33777 |
Kijanimicin
Kijanimicin is an antitumor and antibiotic. Structurally the compound is a unique, large acid enol antibiotic and possesses an unusual in vitro spectrum of activity against some Gram-positive and anaerobic microorganisms. In vivo it has also shown interesting activity against malaria. |
|
DC33778 |
Mecoprop
Mecoprop is an herbicide and used to control broadleaf weeds. |
|
DC33779 |
Chlorpyrifos
Chlorpyrifos is a phosphorothionate that is used as a organophosphate insecticide. |
|
DC33780 |
Sulfamethoxypyridazine
Sulfamethoxypyridazine is an antibacterial that treats vaginal irritation and severe acute thrush. |
|
DC33781 |
Kinsenoside
Kinsenoside is a glycoside with antihyperlipidemic, immunosuppressive, and anti-inflammatory properties. It raises lipolysis mediated by adipose triglyceride lipase and increases hydrolysis of triglycerides in C3H10T1/2 adipocytes. |
|
DC33782 |
Disodium nitrilotriacetate
Disodium nitrilotriacetate is solid used as a chelating agent, which forms coordination compounds with metal ions (chelates) such as Ca2+, Cu2+, and Fe3+. |
|
DC33783 |
Ethiprole
Ethiprole is a chiral phenylpyrazole insecticide. Specifically, it is used to used to control chewing and sucking insects in rice, fruit and vegetable crops. |
|
DC33784 |
Dibutyltin maleate
Dibutyltin maleate is used as a pvc Stabilizer and condensation catalyst. |
|
DC33785 |
Maleic hydrazide
Maleic hydrazide is a herbicide that inhibits the sprouting in vegetables and stored root crops, prevention of sucker production in tobacco plants and growth control of grass, and foliage. |
|
DC33787 |
Cobaltocene
Cobaltocene is used to catalyze the preparation of pyridines from alkynes and nitriles. It is also used as a paint drier and as an oxygen stripping agent. |
|
DC33788 |
Diisobutyl phthalate
Diisobutyl phthalate is a phthalate plasticizer which can be used as a substitute of dibutyl phthalate. |
|
DC33789 |
Kojibiose
Kojibiose is a disaccharide. It is a product of the caramelization of glucose. It is also present in honey. |