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CK1-IN-1

  Cat. No.:  DC33603   Featured
Chemical Structure
1784751-20-7
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Field of application
CK1-IN-1, is a casein kinase 1 (CK1) inhibitor. PUN51207 was reported in patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1784751-20-7
Chemical Name: Pyridine, 4-[2-(1-fluoro-2-naphthalenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-
Synonyms: PUN51207; PUN-51207; PUN 51207; CK1-IN-1; CK1-IN1; CK1-IN 1;
SMILES: FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C5C=CC=CC5=C4F)=N2)C=C1
Formula: C24H15F2N3
M.Wt: 383.4
Purity: >98%
Sotrage: >3 years if stored properly
Description: CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively[1].
Target: CKIδ:15 nM (IC50) CK1ϵ:16 nM (IC50)
References: [1]. Filip LACO,et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO2015119579A1.
MSDS
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COA
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