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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC20961 AA-861 AA-861 (Docebenone) is a potent, selective 5-Lipoxygenase (5-LO) inhibitor with IC50 of 0.8 uM.
DC26090 AAD777 AAD777 (NVP-AAD777.
DC20618 AAI-101 Featured AAI-101 is a novel extended-spectrum β-lactamase inhibitor with activity against many β-lactamases, including some class A and class D carbapenemases.
DC12566 AAK1 inhibitor 1 AAK1 inhibitor 1 (SGC-AAK1-1) is a potent, selective inhibitor of AAK1 and BMP2K/BIKE ((BMP-2 inducible kinase)) that potently targets the ATP-binding site (AAK1 Ki =9.1 nM, BIKE Ki= 17 nM).
DC21862 AAK1 inhibitor 25A AAK1 inhibitor 25A is a potent, selective inhibitor of AAK1 and the closely related kinase BMP2K with Ki of 8 nM (AAK1).
DC12400 AAL(S) AAL(S) is the chiral deoxy analog of the FDA approved drug FTY720, has been shown to inhibit proliferation and apoptosis in several cancer cell lines by activating protein phosphatase 2A (PP2A)..
DC23864 AAL993 Featured AAL993 (ZK260253) is a potent, orally active VEGFR inhibitor with IC50 of 130, 23 and 18 nM for VEGFR-1, 2 and 3, respectively.
DC21981 CD73 inhibitor AB-680 Featured AB680 (AB-680) is a highly potent, selective, reversible inhibitor of CD73 with Ki/IC50 of 4.9/70 pM (hCD73), displays > 10,000-fold selectivity against related ecto-nucleotidases (CD39, NTPDases 2/3/8) and a large panel of unrelated enzymes, receptors, a
DC8161 Xeglyze(Abametapir) Featured Abametapir is the active ingredient of Xeglyze Lotion.
DC12444 ABD-1970 ABD-1970 (ABD1970) is a highly potent, selective Monoacylglycerol lipase (MGLL) inhibitor with IC50 of 13 nM (human MGLL).
DC20620 ABD345 ABD345 is a small molecule inhibitor of RANKL signalling, inhibits TNF-induced NF-κB and MAPK activation and inflammation.
DC23586 Abeprazan Abeprazan is an acid pump inhibitor..
DC24211 Abiraterone (D4A) Featured Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone.
DC20619 ABL127 Featured ABL127 (ML174) is a potent, selective, covalent inhibitor of protein methylesterase 1 (PME-1) with IC50 of 10 nM.
DC20298 ABL-IN-29 ABL-IN-29 is a picomolar ABL kinase inhibitor with IC50 of 0.06/0.11 nM for wt ABL and ABL T315I respectively..
DC20299 ABMA ABMA is a novel broad-spectrum inhibitor of intracellular toxins and pathogens, efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite.
DC21983 Abn-CBD Abn-CBD (Abnormal Cannabidiol) is a selective agonist of GPR55 receptor with EC50 of 2.5 uM, shows no significant activity against CB1 and CB2 receptors (EC50>30 uM).
DC20625 ABT-072 ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b).
DC22258 ABT-080 ABT-080 is a potent FLAP inhibitor that inhibits ionophore-stimulated LTB(4) formation with with IC50 of 20 nM.
DC20626 ABT-089 ABT-089 (Pozanicline) is a potent, selective α4β2 nAChR agonist with Ki of 16 nM.
DC21984 ABT-100 ABT-100 (ABT100) is a highly selective, potent, orally bioavailable inhibitor of farnesyltransferase (FTase).
DC20628 ABT-102 ABT-102 is a potent, highly selective, orally active TRPV1 antagonist that inhibits agonist-evoked increases in intracellular Ca(2+) levels with IC50 of 5-7 nM.
DC20629 ABT-107 ABT-107 is a potent and selective α7 nAChR agonist with Ki of 0.2-0.6 nM for rat or human cortex α7 nAChRs.
DC23537 ABT-288 ABT-288 is a potent, selective and competitive antagonist of H3 receptor with Ki of 1.9/8.2 nM for human/rat H3 respectively.
DC7352 ABT-333 Featured ABT-333 is an NS5B non-nucleoside polymerase inhibitor.
DC10049 Tebanicline(ABT-594) Featured ABT-594 represents a novel class of broad-spectrum analgesics whose primary mechanism of action is activation of the neuronal nicotinic acetylcholine receptors.
DC10723 ABT-702 Featured ABT-702 is a potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase).
DC9262 ABT-719 Featured ABT-719 is a potent bacterial DNA gyrase inhibitor.
DC9261 ABT-719 HCl Featured ABT-719 is a potent bacterial DNA gyrase inhibitor.
DC20630 ABTL0812 ABTL0812 is a novel first-in-class, small molecule that inhibits the Akt/mTORC1 axis and shows antiproliferative effect on tumor cells.

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