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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC24190 Closantel A veterinary anthelmintic with known proton ionophore activities.
DC23096 BCX-4430 A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator.
DC25095 BCX4430 freebase A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator.
DC22579 Retaspimycin hydrochloride A water-soluble derivative of 17-AAG and HSP90 inhibitor.
DC22983 Minnelide A water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival.
DC22868 Propofol A widely used general anesthetic to induce and maintain anesthesia.
DC23233 AH 6809 Featured A xanthone derivative that fuctions as an EP and DP receptor antagonist.
DC22878 LB-205 A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.
DC12702 A1874 Featured A1874 (A-1874) is a nutlin-based and BRD4-degrading PROTAC with DC50 of 32 nM (induce BRD4 degradation in cells).
DC7044 A-205804 A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
DC9574 A-317491 (sodium salt hydrate) Featured A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors.
DC23659 A-357300 A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM, does not inhibit MetAP1 or leucine aminopeptidases at 10 uM.
DC12659 A-381393 Featured A-381393 is a potent and selective agonist of the dopamine D4 receptor.
DC20610 A-395N A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM..
DC22277 A-420983 Featured A-420983 is a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection.
DC20611 A4250 Featured A4250 (A-4250, Odevixibat) is a small molecule ileal bile acid transporter (IBAT) inhibitor for the treatment of cholestatic liver diseases including progressive familial intrahepatic cholestasis and NASH..
DC8406 A-438079 HCl Featured A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.
DC20612 A-68930 hydrochloride A-68930 is a potent, specific, orally bioavailable agonist of the D1 Dopamine receptor with EC50 of 2.5 nM.
DC11372 A-779 Featured A-779 is a peptide antagonist of the Mas receptor, also known as the angiotensin (1-7) (Ang (1-7)) receptor (IC50 = 0.3 nM in a radioligand binding assay).
DC7785 A-790742 A-790742 is a potent human immunodeficiency virus type 1 (HIV-1) protease inhibitor, with 50% effective concentrations ranging from 2 to 7 nM against wild-type HIV-1.
DC20613 A-800141 A-800141 is a potent, highly specific, orally bioavailable MetAP2 inhibitor with IC50 of 12 nM, shows no inhibition for MetAP1 (IC50>30 uM).
DC20614 A-832234 A-832234 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 19 nM..
DC23183 A-836339 A-836339 (A836339) is a potent and selective cannabinoid CB2 receptor agonist with Ki of 0.64 and 0.76 nM for human and rat CB2 receptors, displays 425- and 189-fold selectivity over CB1 receptor, respectively.
DC22721 A-943931 dihydrochloride A-943931 dihydrochloride is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively.
DC22720 A-943931 A-943931 is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively.
DC20616 AA 41612 Featured AA 41612 is a potent, synthetic melanopsin antagonist with IC50 of 15.8 nM, attenuates melanopsin photocurrent in a dose-dependent manner.
DC23202 JNJ-16259685 aA highly potent, selective, non-competitive and centrally active mGluR1 antagonist with Ki of 0.34 nM.
DC23277 AA-115 Featured AA-115 (APG 115) is a potent and orally active MDM2 inhibitor with Ki <1 nM, potently inhibits SJSA-1 cell growth with IC50 of 60 nM.
DC21979 ATF6 agonist compound A147 Featured ATF6 agonist compound A147 is a specific, small molecule agonist of transcription factor ATF6, activates ATF6 and influences differentiation of stem cells.147 has broad antiviral activity against multiple DENV strains and serotypes and that the compound i
DC10165 AA26-9 Featured AA26-9 is a potent and broad spectrum serine hydrolase inhibitor.

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