| Cas No.: | 1762-34-1 |
| Chemical Name: | Abametapir |
| Synonyms: | 5,5'-Dimethyl-2,2'-bipyridine;5,5'-Dimethyl-2,2'-bipyridyl;5,5'-DIMETHYL-2,2'-DIPYRIDYL;5,5′-Dimethyl-2,2′-bipyridine;5-methyl-2-(5-methylpyridin-2-yl)pyridine;2,2'-BIPYRIDINE,5,5'-DIMETHYL;5,5'-dimethyl-2,2'-bipy;5,5'-dimethyl-2,2'-bispyridine;5,5'-dimethyl-bpy;6,6'-Bi-3-picoline;6,6'-Di-3-picoline;6,6'-Di-3-picolyl;Abametapir;Dimethylbipyridyl;2,2'-Bi(5-methylpyridine);5,5-DIMETHYL-2,2-DIPYRIDYL;5,5-Dimethyl-2,2-dipyridine;5,5’-dimethyl-2’-bipyridine;5,5-DIMETHYL-2,2-BIPYRIDINE;2,2'-BIPYRIDINE, 5,5'-DIMETHYL-;6UO390AMFB;5,5 -Dimethyl-2,2 -bipyridine;Xeglyze;Abametapir [USAN:INN];Xeglyze(Abametapir);5dm-Bpy;PubChem24353;Abametapir (USAN/INN) |
| SMILES: | N1C([H])=C(C([H])([H])[H])C([H])=C([H])C=1C1C([H])=C([H])C(C([H])([H])[H])=C([H])N=1 |
| Formula: | C12H12N2 |
| M.Wt: | 184.2371 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2]. |
| In Vitro: | Abametapir is capable of chelating heavy metal ions, including iron, copper, and zinc, and is therefore able to interact with a range of targets within the insect that require metal co-factors for function, including metalloproteinases[2]. |
| References: | [1]. Vernon Morrison Bowles, et al. Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Glob Pediatr Health. 2019; 6: 2333794X19831295. [2]. Vernon M. Bowles, et al. Ovicidal Efficacy of Abametapir Against Eggs of Human Head and Body Lice (Anoplura: Pediculidae). J Med Entomol. 2017 Jan; 54(1): 167-172. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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