| DC7003 |
Apricitabine |
Apricitabine is a novel nucleoside reverse transcriptase inhibitor for the treatment of HIV infection that is refractory to existing drugs |
|
| DC10207 |
Aprotinin |
Aprotinin is a serine protease inhibitor isolated from bovine lung which inhibits trypsin and chymotrypsin with Ki values of 0.06 pM and 9 nM, respectively. |
|
| DC9809 |
APS-3-77 HCl
Featured
|
APS-3-77 is the negative binder of KSR2. |
|
| DC21999 |
APTO-253 hydrochloride |
APTO-253 is a small molecule inducer of KLF4, stabilizes G-quadruplex DNA and reduces MYC mRNA expression and protein levels. |
|
| DC20672 |
APX001A
Featured
|
APX001 (APX 001A;E1210) is a novel broad-spectrum antifungal agent that inhibits the fungal protein Gwt1, demonstrates significantly acitive MIC50 and MIC90 values of 0.004 and 0.031 ug/ml (16 strains of C. auris). |
|
| DC11194 |
APX2009 |
APX2009 (APX-2009) is a novel potent inhibitor of reduction-oxidation factor 1-apurinic/apyrimidinic endonuclease 1 (Ref-1/APE1) with IC50 of 0.45 uM for redox EMSA inhibition. |
|
| DC11195 |
APX2014 |
APX2014 (APX-2014) is a novel potent inhibitor of reduction-oxidation factor 1-apurinic/apyrimidinic endonuclease 1 (Ref-1/APE1) with IC50 of 0.2 uM for redox EMSA inhibition. |
|
| DC23311 |
AQ-101 |
AQ-101 is a novel small-molecule anthraquinone analog that induces MDM2 protein degradation (Kd=0.37 uM) through a self-ubiquitination and proteasome-mediated mechanism, leading to activation of p53. |
|
| DC12155 |
AQ-13 dihydrochloride |
AQ-13 dihydrochloride is an aminoquinoline antimalarial drug that is effective against chloroquine-resistant strains of Plasmodium falciparum. |
|
| DC20673 |
AQW-051 |
AQW-051 is a novel, potent and selective, orally bioavailable, brain-penetrant α7 nAChR partial agonist with pKd of 7.56. |
|
| DC23139 |
AQX 1125 |
AQX 1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator. |
|
| DC20674 |
AR03 |
AR03 (AR-03, AR 03, Ape1 repair inhibitor 03) is a novel small molecule inhibitor of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) endonuclease activity with IC50 of 5 uM. |
|
| DC8764 |
AR 231453
Featured
|
AR231453 is a potent and selective small molecule agonist of GPR119 that enhances glucose-dependent insulin secretion and glucagon-like peptide 1 (GLP-1) release; Antidiabetic agent. |
|
| DC22493 |
ARA-290(Cibinetide)
Featured
|
ARA-290 (Cibinetide) is a non-erythropoietic erythropoietin (EPO) derivative. |
|
| DC8888 |
Ara-G
Featured
|
Ara-G (9-β-D-Arabinofuranosyl guanine) is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic. |
|
| DC10862 |
Aramchol |
Aramchol, also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. |
|
| DCAPI1051 |
Arbidol HCl (Umifenovir)
Featured
|
Umifenovir is currently being investigated as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections in combination with both currently available and investigational HIV therapies. Arbidol hydrochloride (Umifenovir hydroc |
|
| DC20675 |
AR-C102222 |
AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively. |
|
| DC22544 |
AR-C155858 |
AR-C155858 is a potent monocarboxylate transporter MCT1 and MCT2 with Ki of 2.3 nM and <10 nM, displays no activity at MCT4. |
|
| DC20265 |
Arctigenin
Featured
|
Arctigenin is an extract from A. lappa, a burdock plant traditionally used in Japanese Kampo medicine for its antioxidant, anti-inflammatory, |
|
| DC9659 |
Arctiin(NSC 315527)
Featured
|
Arctiin, a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. |
|
| DC12359 |
Arg-AMS |
Arg-AMS is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes. |
|
| DCAPI1329 |
Argatroban
Featured
|
Argatroban |
|
| DC8841 |
Argatroban monohydrate
Featured
|
Argatroban monohydrate is a direct, selective thrombin inhibitor. |
|
| DC9645 |
(+)-Arglabin
Featured
|
Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella; anticancer natural compound. |
|
| DC23605 |
AR-HO47108 |
AR-HO47108 is a potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 7.0. |
|
| DC10110 |
ARM390 Hydrochloride
Featured
|
ARM390 is a non-peptidic, low-internalizing δ-selective opioid receptor agonist. |
|
| DC20677 |
ARN 077 |
ARN077 is the first potent, selective N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 7 nM on both rat NAAA and human NAAA. |
|
| DC12569 |
ARN14494 |
ARN14494 (ARN-14494) is a potent, small molecule serine palmitoyltransferase (SPT) inhibitor with IC50 of 27.3 nM. |
|
| DC22000 |
ARN19874 |
ARN19874 (ARN-19874) is the first selective, cell-active inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) with IC50 of 33.7 uM. |
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