Cat. No. | Product name | CAS No. |
DC22674 |
TCV-309
A highly potent and selective platelet activating factor (PAF) antagonist. |
131311-25-6 |
DC22560 |
TCV-309 chloride
A highly potent and selective platelet activating factor (PAF) antagonist. |
121494-09-5 |
DC24134 |
GCGR-IN-1
A highly potent glucagon receptor antagonist.. |
503559-84-0 |
DC24083 |
4-IBP
Featured
A highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively. |
155798-08-6 |
DC21813 |
MT-7716
A highly potent, brain-penetrating ORL1 receptor (NOP receptor) agonist with Ki of 0.76 and 0.50 nM for rat and human ORL1 receptors, respectively. |
1215859-93-0 |
DC21258 |
LY 2812223
A highly potent, functionally selective mGlu2 receptor agonist with EC50 of 13.6 nM in GTPγS functional binding assay. |
1311385-20-2 |
DC23409 |
AZD 8683
A highly potent, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, inhibits M3 receptor in guinea pig trachea with pA2 of 9.4. |
1194737-07-9 |
DC22822 |
Saxagliptin hydrate
A highly potent, long-acting, orally active DPP4 inhibitor with Ki of 0.6 nM. |
945667-22-1 |
DC23848 |
YM-359445
A highly potent, orally active VEGFR-2 inhibitor with IC50 of 8.5 nM, without activity against PKA, PKCα, PDK-1 and JNK3 (IC50>1 uM). |
1020067-28-0 |
DC24063 |
Cediranib maleate
Featured
A highly potent, orally bioavailable, pan-VEGFR inibitor with IC50 of 1, 5, 3 nM for VEGFR1, 2, 3, respectively. |
857036-77-2 |
DC21588 |
RS 102221
A highly potent, selective 5-HT2C receptor antagonist with pKi of 8.4 and 8.5 for human and rat 5-HT2C, respectively. |
187397-18-8 |
DC21690 |
SR 144528
A highly potent, selective and orally active antagonist of CB2 receptor with Ki of 0.6 nM. |
192703-06-3 |
DC23424 |
RO 5256390
Featured
A highly potent, selective and orally bioavailable trace amine-associated receptor 1 (TRRA1) full agonist with EC50 of 18 nM, >500-fold selectivity over human adrenergic α2A receptor. |
1043495-96-0 |
DC21582 |
RO 5263397
A highly potent, selective and orally bioavailable trace amine-associated receptor 1 (TRRA1) partial agonist with EC50 of 17 nM, >1,000-fold selectivity over human adrenergic α2A receptor. |
1357266-05-7 |
DC20333 |
Cdc7 inhibitor 7c
A highly potent, selective and time-dependent Cdc7 kinase inhibitor with IC50 of 0.7 nM with slow dissociation property, with 200-fold and >14,000-fold selectivity over CDK2 and ROCK1, respectively. |
1330781-04-8 |
DC22919 |
POL3026
A highly potent, selective beta-hairpin mimetic CXCR4 inhibitor with IC50 of 1.2 nM in Ca2+ flux assay. |
918660-21-6 |
DC22918 |
POL2438
A highly potent, selective beta-hairpin mimetic CXCR4 inhibitor with IC50 of 1.9 nM in Ca2+ flux assay. |
790223-00-6 |
DC22342 |
MK-3207
A highly potent, selective CGRP receptor antagonist with Ki of 21 pM in in vitro binding assay and IC50 of 0.12 nM in cell-based functional assay. |
957118-49-9 |
DC20924 |
CPI-1205
A highly potent, selective EZH2 inhibitor with biochemical IC50 of 2 nM, cellular EC50 of 32 nM. |
1621862-70-1 |
DC20598 |
2-BFI hydrochloride
A highly potent, selective imidazoline I2 receptor agonist with Ki of 9.8 nM, enhances supraspinal morphine analgesia in mice.. |
89196-95-2 |
DC23339 |
NTRC 00660
A highly potent, selective inhibitor of checkpoint kinase TTK/Mps1 with IC50 of 0.6 nM. |
1817791-73-3 |
DC23478 |
MRS-2365
A highly potent, selective P2Y1 receptor agonist with EC50 of 1.2 nM. |
436847-09-5 |