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Cat. No. Product Name Field of Application Chemical Structure
DC23501 Finazine Finazine is a high-affinity, brain penetrant sigma-1 and sigma 2 receptor ligand with Ki of 2.6 nM and 46 nM, respectively.
DC12637 Finerenone Featured Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.
DC8936 Fingolimod Fingolimod(FTY720 free base) is a S1P antagonist with IC50 of 0.033 nM.
DC11309 Fipronil Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 and 1,600 nM for cockroach and rat receptors, respectively).
DC8200 Firategrast(SB-683699) Featured Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS).
DC8917 Firocoxib Firocoxib(ML 1785713) is a potent and selective cyclooxygenase (COX)-2 inhibitor with IC50 of 0.13 uM, 58 fold sensitivity for COX2 VSCOX1.
DC21015 FIT-039 Featured FIT-039 is a potent, selective CDK9 inhibitor with IC50 of 5.8 uM for CKD9/cyclin T1, suppresses the replication of HSV-1 (IC50=0.69 uM).
DC9845 FITM Featured FITM is a nove mGlu1 inhibitor. FITM shows high affinity (Ki = 2.5 nM, fig. S2) and selectivity for mGlu1 over mGlu5.
DC20386 Pioglitazone Featured Pioglitazone is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
DC21016 FJ 5002 FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077.
DC7112 FK 3311 Featured FK 3311 is a selective inhibitor of COX-2; antiinflammatory agent.
DC22093 FKGK18 FKGK18 (FKGK18) is a potent, selective inhibitor of iPLA2 (group VIA Ca2+-independent phospholipase A2) with IC50 of 50 nM.
DC10845 FL-411 Featured FL-411 is a selective BRD4 inhibitor.
DC20019 Flagelin 22(TFA) (Flagellin 22(TFA)) Flagelin 22 TFA, a fragment of bacterial flagellin, is an effective elicitor in both plants and algae.
DC10972 Flavokawain B Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression.
DC2014 Flavopiridol Featured Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM, and CDK7 with IC50 of 300 nM.
DC8780 Flavopiridol Hydrochloride Featured Flavopiridol hydrochloride competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA.
DC11414 Flavoxate Hydrochloride Featured Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.
DC9623 Flecainide (acetate) Featured Flecainide(Tambocor) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
DCAPI1347 Fleroxacin (Quinodis) Fleroxacin (Quinodis)
DC7415 FLI-06 Featured FLI-06 is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2.3 μM).
DC9321 Flibanserin Featured Flibanserin is a novel multifunctional serotonin agonist and antagonist (MSAA) that improves sexual functioning in premenopausal women who suffer from reduced sexual interest and desire.
DC8726 FLLL31 Featured FLLK31 is a potent and selective inhibitor of the STAT3 signaling pathway.
DC7751 FLLL32 Featured FLLL32, a novel curcumin analogue, is a potent STAT3 inhibitor.
DC8164 Gilteritinib(ASP2215) Featured FLT3/AXL inhibitor
DC8230 FLT3-IN-1(SKLB4771) Featured FLT3-IN-1(SKLB4771) is a novel potent and selective Flt3 inhibitor with IC50 of 10 nM; against FLT3-ITD-expressing MV4-11 cells with IC50 of 6 nM.
DC11780 FLT3-IN-5e FLT3-IN-5e is a nove potent, selective FLT3 inhibitor with Kd of 3.6 nM, IC50 of <6 nM.
DC9060 Flubendazole Flubendazole is a potent broad spectrum anthelmintic.
DCAPI1375 Fluconazole Fluconazole
DCAPI1108 Flucytosine (Ancobon) Flucytosine (5-Fluorocytosine, 5-FC, Ancobon) is an antifungal drug with IC50 of 0.12 μg/mL in C.albicans.

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