| DC20381 |
Fasentin
Featured
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Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1. |
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| DC22759 |
FAS-IN-1 |
FAS-IN-1 is a potent inhibitor of fatty acid synthase (FAS) wtih IC50 of 10 nM.. |
|
| DC10403 |
FAS-IN-1 Tosylate |
FAS-IN-1 tosylate is a potent inhibitor of fatty acid synthase (FAS) extracted from patent WO 2012064642 A1, compound 29; has an IC50 of 10 nM. |
|
| DC7413 |
Fasudil-HA
Featured
|
Fasudil Hcl(HA-1077; AT-877) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively. |
|
| DC10213 |
Fatostatin
Featured
|
Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. |
|
| DC23119 |
FB23-2(FTO Demethylase inhibitor FB23-2)
Featured
|
FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM. |
|
| DC23507 |
FC131
Featured
|
FC131 (cyclo(-D-Tyr-Arg-Arg-Nal-Gly-)) is a selective, cyclopentapeptide CXCR4 antagonist with IC50 of 126 nM, exhibits anti-HIV activity in assays using NL4-3 and IIIB strains with EC50 of 21 nM.. |
|
| DC9753 |
FCCP
Featured
|
FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria,that disrupts ATP synthesis by transporting protons across cell membranes. |
|
| DC23678 |
FCPR03 |
FCPR03 is a novel potent, selective PDE4 inhibitor with IC50 of 60, 31 and 47 nM for PDE4CAT (PDE4 catalytic domain), PDE4B1 and PDE4D7, respectively. |
|
| DC25015 |
FD-44 |
FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model. |
|
| DC26037 |
FDL-169
Featured
|
FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector being developed by Flatley Discovery Lab for treating cystic fibrosis (CF) patients who carry the F508del mutation |
|
| DCAPI1591 |
FEBUXOSTAT
Featured
|
FEBUXOSTAT is an inhibitor xanthine oxidase and xanthine dehydrogenase |
|
| DC5099 |
Felbamate
Featured
|
Felbamate (Felbatol) is an anticonvulsant drug used in the treatment of epilepsy. |
|
| DC9105 |
Felodipine |
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. |
|
| DC20382 |
FEN1-IN-1 |
FEN1-IN-1 is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM. |
|
| DC20383 |
FEN1-IN-C20 |
FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM. |
|
| DCAPI1181 |
Fenbendazole (Panacur) |
Fenbendazole (Panacur) |
|
| DC9086 |
Fenofibrate |
Fenofibrate is PPARα agonist with EC50 of 18 μM and 30 μM for mouse and human PPARα, respectively. |
|
| DC9065 |
Fenofibric acid |
Fenofibric acid is a lipid regulating agent available as delayed release capsules for oral administration. |
|
| DC9424 |
Fenoldopam (mesylate)
Featured
|
Fenoldopam(SKF 82526) mesylate is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial agonist.
|
|
| DCAPI1157 |
Fenoprofen calcium |
Fenoprofen calcium |
|
| DC8684 |
Fenoxaprop-P-ethyl
Featured
|
Fenoxaprop-P-ethyl is a post-emergent phenoxy herbicide of the aryloxyphenoxy propionate group. |
|
| DC7714 |
Fenretinide (4-HPR)
Featured
|
Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death. |
|
| DCAPI1326 |
Fenticonazole nitrate |
Fenticonazole nitrate |
|
| DC12246 |
Feretoside |
Feretoside, a phenolic compound extracted from the barks of E. ulmoides, is a HSP inducer which act as cytoprotective agent. |
|
| DC10742 |
Ferrostatin-1 (Fer-1)
Featured
|
Ferrostatin-1 is a selective inhibitor of erastin induced ferroptosis with EC50 value of 60 nM. |
|
| DC20102 |
Ferulic acid methyl ester
Featured
|
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical s |
|
| DC23516 |
Fesoterodine |
Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. |
|
| DC23515 |
Fesoterodine maleate |
Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. |
|
| DC8912 |
Fesoterodine fumarate
Featured
|
Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist. |
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