| DC11278 |
Fevipiprant
Featured
|
Fevipiprant(QAW039) is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change. |
|
| DC8069 |
Fexaramate
Featured
|
Fexaramate is a potent, selective farnesoid X receptor agonist. |
|
| DC8085 |
Fexaramine
Featured
|
Fexaramine is a potent, selective FXR activator. |
|
| DC8070 |
Fexarene
Featured
|
Fexarene is a potent, selective farnesoid X receptor agonist. |
|
| DC8071 |
Fexarine
Featured
|
Fexarine is a potent, selective farnesoid X receptor agonist. |
|
| DC7811 |
Fexinidazole
Featured
|
Fexinidazole is a new Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness |
|
| DC9175 |
Fexofenadine Hydrochloride
Featured
|
Fexofenadine is a third-generation antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. |
|
| DC21010 |
FF-10501-01 |
FF-10501-01 is a potent, selective and orally available IMPDH inhibitor. |
|
| DC10973 |
FF-10502 |
FF-10502 (FF-10502-01) is a pyrimidine nucleoside antimetabolite that shows growth inhibition of pancreatic cancer cell lines with IC50 of 60-330 nM. |
|
| DC23627 |
FFN-206 dihydrochloride |
FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling |
|
| DC8195 |
FG2216
Featured
|
FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo. |
|
| DC5193 |
Roxadustat(FG-4592)
Featured
|
FG-4592 is an HIF αprolyl hydroxylase inhibitor, stabilizes HIF-2 and induces EPO production. |
|
| DC10128 |
FGF401( Roblitinib)
Featured
|
FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. |
|
| DC9933 |
FGFR4-IN-1 |
FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM. |
|
| DC21012 |
FGI-103 |
FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
|
| DC21013 |
FGI-104 |
FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
|
| DC7637 |
FH1(BRD-K4477)
Featured
|
FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes. |
|
| DC7414 |
FH535
Featured
|
FH535 is a compound that suppresses both Wnt/beta-catenin and peroxisome proliferator-activated receptor (PPAR) signaling. |
|
| DC20384 |
Fhit-IN-15 |
Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells.. |
|
| DC20385 |
FICZ
Featured
|
FICZ is a high affinity aryl hydrocarbon receptor (AhR) agonist with Kd of 70 pM. |
|
| DC21673 |
Fidarestat |
Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats.. |
|
| DC1057 |
Fidaxomicin (Dificid)
Featured
|
Fidaxomicin, is an antibiotic that belongs to the class of macrocylic antibiotics. |
|
| DC8330 |
FIIN-2
Featured
|
FIIN-2 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. |
|
| DC9642 |
FIIN-3
Featured
|
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. |
|
| DC21817 |
Filaminast |
Filaminast (WAY-PDA-641. |
|
| DC21482 |
Filibuvir |
Filibuvir (PF-00868554. |
|
| DC9349 |
Fimasartan
Featured
|
Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure.
|
|
| DC11432 |
FimH inhibitor 5h |
FimH inhibitor 5h is a potent and orally active FimH inhibitor. |
|
| DC10522 |
FIN56
Featured
|
FIN56 is a specific inducer of ferroptosis. |
|
| DC8847 |
Finafloxacin (BAY35-3377)
Featured
|
Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. |
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