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Cat. No. Product Name Field of Application Chemical Structure
DC21116 HJC0197 Featured HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP.
DC21118 HJC 0726 HJC 0726 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor, inhibits cAMP-mediated EPAC2 GEF activity with IC50 of 1.0 uM.
DC10626 HJC0152 HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor with remarkably improved aqueous solubility.
DC21117 HJC-0338 HJC-0338 is a potent and specific EPAC2 antagonist with IC50 of 0.4 uM for competing with 8-NBD-cAMP in binding EPAC2.
DC7638 HJC-0350 Featured HJC-0350 is a selective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.
DC11366 HKI 357 HKI 357 is an irreversible dual inhibitor of the EGF receptor tyrosine kinases EGFR and HER2 (IC50s = 34 and 33 nM, respectively).
DC21119 HL001 HL001 (HL 001) is a potent cyclophilin A (CypA) inhibitor with IC50 of 31.6 nM, induces NSCLC cell cycle arrest and apoptosis via restoring p53 expression.
DC9678 HLCL-61 hydrochloride Featured HLCL-61 is a first-in-class small-molecule inhibitor of PRMT5 for treatment of acute myeloid leukemia.
DC21977 HlyU inhibitor CM14 HlyU inhibitor CM14 (1025E12) is a specifc, small-molecule inhibitor of transcriptional regulator HlyU activity with EC50 of 30.97 uM, inhibits HlyU from binding to target DNA by covalently modifying Cys30.
DC10414 HM30181(Encequidar) Featured HM30181 is a potent and selective inhibitor of P-glycoprotein.
DC12074 HM30181 mesylate Featured HM30181 mesylate is a competitive and potent P-glycoprotein inhibitor.
DC8819 Olmutinib (HM61713; BI-1482694) Featured HM-61713 (BI-1482694) is an orally available small molecule, mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity.
DC10517 HMN-154 Featured HMN-154 is a novel benzenesulfonamide anticancer compound; inhibits KB and colon38 cells with IC50 values of 0.0026 and 0.003 μg/mL, respectively.
DC9957 HMN-176 Featured HMN-176 is a stilbene derivative which inhibits mitosis without significant effect on tubulin polymerization.
DC8768 HMN-214 Featured HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM.
DC20407 HMPC HMPC is a novel bacteriostatic agent that shows bacteriostatic activity against S. aureus (MIC=4 μg/ml) and rescues Caenorhabditis elegans from S. aureus infection.
DC22107 HMS-101 HMS-101 (HMS101) is a potent, selective mutant IDH1 inhibitor, the IC50 is significantly lower in mouse bone marrow cells transduced with IDH1mut compared with IDH1wt (1 uM vs 12 uM, respectively).
DC6314 Icatibant acetate Featured HOE-140 (Icatibant) is a potent and selective bradykinin B2 receptor antagonist (pA2 = 9.04). Also inhibits aminopeptidase N (Ki = 9.1 μM).
DC9415 Hoechst 33342 (trihydrochloride) Hoechst 33342 3Hcl(HOE 33342 3Hcl) is an AT-specific DNA minor groove ligand used fluorochrome for visualizing cellular DNA.
DC9418 Hoechst 33258 analog Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.
DC22129 HOIPIN-1(JTP-0819958;HOIP inhibitor-1) Featured HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the N
DC22108 HOIPIN-8 Featured HOIPIN-8 (HOIP inhibitor-8) is a potent chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=11 nM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pa
DC9650 Homoharringtonine Featured Homoharringtonine(HHT) is a cytotoxic alkaloid from the evergreen tree.
DC10177 Homoplantaginin Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia with antiinfammatory and antioxidant properties.
DC5908 Honokiol Featured Honokiol(NSC-293100), a hydroxylated biphenyl compound isolated from the Chinese herb Magnolia officinalis, has been reported to have anticancer activities in a variety of cancer cell lines.
DC12154 Hosenkoside A Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.
DC12148 Hosenkoside B Hosenkoside B is a baccharane glycoside isolated from the seeds of impatiens balsamina.
DC12152 Hosenkoside F ((+)-Hosenkoside F) Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina.
DC12153 Hosenkoside K Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.
DC12149 Hosenkoside M ((+)-Hosenkoside M) Hosenkoside M is a baccharane glycoside isolated from the seeds of impatiens balsamina.

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