| DC1103 |
Hesperadin
Featured
|
Hesperadin inhibits Aurora B and T. brucei Aurora kinase-1 (TbAUK1) with IC50 of 250 nM and 40 nM, respectively. |
|
| DCAPI1218 |
Hesperidin |
Hesperidin |
|
| DC10967 |
HET0016 |
HET0016 (HET-0016) is a potent, selective inhibitor of CYP4A, potently inhibits the formation of 20-HETE with IC50 of 8.9 nM in human renal microsomes. |
|
| DC12717 |
Hetrombopag |
Hetrombopag is a potent, selective, orally-active Thrombopoietin (TPO) receptor agonist. |
|
| DC12227 |
Hexacosanoic acid |
Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis. |
|
| DC12195 |
Hexadimethrine bromide
Featured
|
Hexadimethrine bromide is a cationic polymer discovered to enhance retroviral transduction. |
|
| DC12306 |
Hexamethylquercetagetin |
Hexamethylquercetagetin is a polymethoxylated flavone in peels of citrus cultivars. |
|
| DC8680 |
Hexaminolevulinate hydrochloride |
Hexaminolevulinate hydrochloride is a fluorescent agent, has approved for cystoscopic detection of papillary bladder cancer. |
|
| DC12707 |
Hexokinase 2 modulator Comp-1 |
Hexokinase 2 modulator Comp-1 is a potent, selective small molecule modulator of Hexokinase 2 (HK2) interaction with the mitochondria, selectively dissociates HK2 from VDAC1 in vitro with IC50 of 92 nM. |
|
| DC21904 |
HG-12-6 |
HG-12-6 is a small-molecule inhibitor that bind preferentially to unphosphorylated IRAK4 with IC50 of 165.1 nM, displays 15-fold selectivity over phosphorylated IRAK4 (IC50=2876 nM). |
|
| DC10652 |
HG-14-10-04
Featured
|
HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM. |
|
| DC23141 |
HG6-64-1 |
HG6-64-1 is a potent dual TAK1 and MAP4K2 ((germinal center kinase, GCK)) inhibitor with IC50 of 41 nM and 98 nM, respectively. |
|
| DC20405 |
HG-7-27-01 |
HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases.. |
|
| DC21379 |
HG-7-92-01(NG25)
Featured
|
HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.. |
|
| DC10108 |
HG-9-91-01
Featured
|
HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively. |
|
| DC26060 |
gly-arg p-nitroanilide dihydrochloride
Featured
|
H-Gly-Arg-pNA is a colorimetric substrate for thrombin. |
|
| DC8846 |
HhAntag
Featured
|
HhAntag is a GLI1-Mediated transcription inhibitor. |
|
| DC20406 |
HIF2α-IN-2 |
HIF2α-IN-2 is a potent, selective, allosteric inhibitor of HIF-2α PAS-B domain with Kd of 81 nM, shows high selectivity and does not affect HIF-1 function. |
|
| DC7148 |
LY 379268
Featured
|
Highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. |
|
| DC20083 |
H-Ile-Pro-Pro-OH
Featured
|
H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides. |
|
| DC23298 |
Hinokitiol |
Hinokitiol (4-Isopropyltropolone. |
|
| DC23710 |
Hippuristanol |
Hippuristanol is a potent, steroid inhibitor of eukaryotic initiation factor 4A (eIF4A), results in cell cycle arrest at G1 phase, and induces caspases activation and apoptosis. |
|
| DC10585 |
Hispidol
Featured
|
Hispidol ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 µM. |
|
| DC10171 |
Hispidulin
Featured
|
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM. |
|
| DCAPI1505 |
Darunavir
Featured
|
Darunavir(TMC114) is an HIV protease inhibitor,showed potent activity against COVID-19(SARS-COV-2) . |
|
| DC8163 |
Fostemsavir(BMS-663068)
Featured
|
HIV-1 attachment inhibitor,a prodrug of the small-molecule inhibitor BMS-626529 |
|
| DC23258 |
HIV-1 inhibitor 18A |
HIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry, specifically inhibits the entry of a wide range of HIV-1 isolates with mean IC50 of 6.4 uM. |
|
| DC9473 |
HIV-1 integrase inhibitor |
HIV-1 integrase inhibitor ((Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid) is uesful for anti-HIV. |
|
| DC23263 |
HIV-1 Integrase Inhibitor 7 |
HIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 0.58 uM, antiviral activity EC50 of 0.76 uM.. |
|
| DC9472 |
HIV-1 integrase inhibitor 2 |
HIV-1 integrase inhibitor, in the treatment of human immunodeficiency virus (HIV) infection. |
|
