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Cat. No. Product Name Field of Application Chemical Structure
DC23634 HBT1 HBT1 is a novel potent AMPA receptor potentiator with lower agonistic effect compared with LY451395 and OXP1..
DC20917 HBV Capsid inhibitor 3711 HBV Capsid inhibitor 3711 (Compound 3711) is a nonnucleosidic HBV inhibitor, inhibits hepatitis B virus replication by inducing genome-free capsid formation.
DC10354 HBX 19818 Featured HBX 19818 is a selective USP7 inhibitor with IC50 of 28.1 uM .
DC23783 HBX 28258 HBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM, exhibits high selectivity over other USP members, such as USP8, USP5, USP2, and USP20 (IC50 >200 uM), and no activity against UCH-L1, UCH-L3 and SENP1.
DC8207 HBX41108 Featured HBX 41108 is an inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM).
DC5200 HC-030031 Featured HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.
DC12197 HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) HC-056456 is an effective but not perfectly-selective blocker of CatSper channels. The [Na+]i rise is slowed by HC-056456 (IC50~3 µM).
DC11416 HC-067047 Featured HC-067047 is a potent and selective TRPV4 antagonist with IC50 values of 48 ± 6 nM, 133 ± 25 nM, and 17 ± 3 nM, respectively in human, rat, and mouse. Also inhibits the endogenous TRPV4-mediated response to 4α-PDH (IC50 = 22 nM).
DC21108 HC-070 HC-070 is a potent, selective, orally active inhibitor of TRPC4 and TRPC5 channel with IC50 of 9.3 and 46 nM (calcium influx inhibition), respectively.
DC12620 hClpP activator D9 Featured hClpP activator D9 is a potent and species-selective activator of human ClpP (hClpP, human Caseinolytic protease P) by mimicking the natural chaperone ClpX..
DC8828 HDAC inhibitor IV Featured HDAC inhibitor IV is a cell-permeable pimeloylanilide compound that acts as a FXN- (frataxin gene) specific HDAC (histone deacetylase) inhibitor.
DC10932 HDAC6 degrader 9c HDAC6 degrader 9c (dHDAC6 9c) is a bifunctional molecule (dHDAC6) that could selectively degrade HDAC6, by conjugating non-selective HDAC inhibitor to a thalidomide-type E3 ligase ligand.
DC20401 HDAC6-AR-IN-10 HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM).
DC11594 HDAC8-IN-20a HDAC8-IN-20a is a potent, selective HDAC8 inhibitor with IC50 of 27 nM.
DC10596 Lavendustin C (HDBA) Featured HDBA, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 µM.
DC10613 NVP-HDM201(Siremadlin ) Featured HDM201 is an orally bioavailable human double minute 2 homolog (HDM2) inhibitor with potential antineoplastic activity.
DC21113 HEC72702 HEC72702 is a novel potent, orally active inhibitor of HBV capsid assembly, inhibits HBV-DNA levels in HepG.2.2.15 cells with IC50 of 39 nM.
DC21114 HEC-73543 HEC-73543 is a novel potent, selective, orally bioavailable FLT3 inhibitor for the treatment of refractory acute myeloid leukemia (AML).
DC9921 Hederacoside C Featured Hederacoside C is a principal bioactive pharmaceutical ingredient of Hedera helix leaf that can treat respiratory disorders, because of its expectorant, bronchodilator, antibacterial, and bronchospasmolytic effects.
DC9823 Hederagenin Featured Hederagenin a triterpenoid saponin, is used to study the properties of triterpenoid saponins as biopesticides that prevent fungal growth, bacterial growth, and viral plant diseases.
DC20402 Hedgehog-IN-7d Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM..
DC21414 Helenalin Helenalin (NSC 85236) is a sesquiterpene lactone that covalently targets Cys38 on p65 transcription factor in the canonical NF-κB signaling pathway.
DC21109 Hemicholinium-3 Hemicholinium-3 (HC-3) is a competitive, small molecule inhibitor of choline kinase (ChoK) with ex vivo IC50 of 500 uM, also bolcks the sodium and chloride-dependent transport system and affects choline acetyltransferase.
DC24152 Hemin Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.
DC21115 TD-1 Featured Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling.
DC12294 Heparin lithium salt Featured Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII).
DC10422 Heptamethine cyanine dye-1 Heptamethine cyanine dye-1 is a near-infrared cyanine dye for fluorescence imaging in biological systems.
DC20403 HER2-IN-2 HER2-IN-2 is a potent, selective HER2 inhibitor, only shows potent inhibition for EGFR and Abl in a panel of kinases.
DC20404 HER2-IN-3 HER2-IN-3 is a type I HER2 inhibitor that has a similar profile to HER2-IN-2.
DC23730 Herboxidiene Herboxidiene (GEX1A, TAN-1609) is a polyketide molecule first isolated from the fermentation broth of Streptomyces chromofuscus, shows in vitro antitumor activity by targeting the SF3B protein in the splicesosome.

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