Products

You can also try the following methods, and our professionals will serve you Customized Consultation

Cat. No.	Product Name	Field of Application
DC23259	IMB-301	IMB-301 (NSC 301209) is a small molecule inhibitor that target the binding interface of the HIV-1 Vif/hA3G complex, inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM).
DC8770	IMD-0354 Featured	IMD-0354 is a synthetic selective NF-kB inhibitor.
DC23731	iMDK	iMDK is a small molecule inhibitor of the growth factor Midkine (MDK) that suppresses the endogenous expression of MDK but not other growth factors such as PTN or VEGF.
DC8890	Imidafenacin Featured	Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).
DC20211	Imidazole;1,3-diazole; glyoxaline; 1,3-diazacyclopenta-2,4-diene	Imidazole is a heterocyclic aromatic organic compound. It can be incorporated into many important biological molecules and acts as a corrosion inhibitor for industrial applications.
DC22092	Imidazole ketone erastin（IKE） Featured	Imidazole ketone erastin (IKE, Ferroptosis inducer IKE) is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications.
DC20207	Imidazole-4(5)-acetic Acid Hydrochloride	Imidazole-4(5)-acetic Acid Hydrochloride is a competitive antagonist at GABAC receptors.
DC21292	Imipenem	Imipenem (MK-0787) is a broad-spectrum, semi-synthetic beta-lactam carbapenem that has broad antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains..
DC8988	Imiquimod Featured	Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas.
DC10406	Imisopasem manganese	Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.
DC21145	IMM-01	IMM-01 is a small molecule agonist of mammalian Diaphanous (mDia)-related formins that disrupts diaphanous inhibitory domain (DID) and diaphanous autoregulatory domain (DAD) interaction with IC50 of 140 nM.
DC21146	IMM-02	IMM-02 is a small molecule agonist of mammalian Diaphanous (mDia)-related formins that disrupts diaphanous inhibitory domain (DID) and diaphanous autoregulatory domain (DAD) interaction with IC50 of 99 nM.
DC10806	IMP-1088	IMP-1088 is a novel picomolar dual inhibitor of the human N-myristoyltransferases NMT1 and NMT2
DC10027	Importazole Featured	Importazole is an inhibitor of importin-β transport receptors.
DC8874	7-TACA	Impurity D of Cefoperazone
DC9756	IMR-1 Featured	IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis.
DC9785	IMR-1A Featured	IMR-1A is the metabolite of IMR-1. IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μmol/L.
DC12578	IMTPPE Featured	IMTPPE (SID3712502) is a novel small molecule capable of inhibiting androgen receptor (AR) transcriptional activity (IC50=1 uM) and protein level in C4-2 prostate cancer cells.
DC8450	(R)-Equol	In contrast to the estrogen receptor (ER) selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ERα and ERβ with Ki values of 27.4 and 15.4 nM, respectively.
DC10730	Inarigivir(ORI-9020,SB-9000) Featured	Inarigivir(SB-9000) is a novel dinucleotide, evaluated in transgenic mice expressing hepatitis B virus (HBV), significantly reduced liver HBV DNA。
DC7015	INCB024360 analogue(IDO-IN-1) Featured	INCB024360 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical properties, which is poised to start clinical trials in cancer patients.
DC10918	INCB053914	INCB053914 (INCB-053914) is a novel potent, and selective ATP-competitive, pan-PIM kinase inhibitor with IC50 of 0.24/30.0/0.12 nM for PIM1/2/3, respectively.
DC23397	INCB054329	INCB054329 is a novel potent, orally bioactive BET inhibitor that inhibits binding of BRD2, BRD3 and BRD4 to an acetylated histone H4 peptide with low nanomolar potency.
DC20176	INCB057643 Featured	INCB057643 is a BET inhibitor that binds to the acetylated lysine recognition motifs found in the BRD of BET proteins, thereby preventing the interaction between the BET proteins and acetylated lysines on histones.
DC26025	INCB086550(INCB-086550) Featured	INCB086550 is an orally available, small molecule inhibitor of PD-L1 with potential immune checkpoint inhibitory and antineoplastic activities. In vitro, INCB086550 selectively and potently blocked the PD-L1/PD-1 interaction, induced PD-L1 dimerization and internalization, and induced stimulation-dependent cytokine production in primary human immune cells. In vivo, INCB086550 reduced tumor growth in CD34+ humanized mice and induced T-cell activation gene signatures, consistent with PD-L1/PD-1 pathway blockade. Preliminary data from an ongoing phase I study confirmed PD-L1/PD-1 blockade in peripheral blood cells, with increased immune activation and tumor growth control.
DC21497	INCB10820	INCB10820 (PF-4178903) is a potent, selective, orally bioavailable dual CCR2 and CCR5 antagonist with binding IC50 of 3.0 nM and 5.3 nM, respectively.
DC7167	Capmatinib(INCB28060) Featured	INCB28060 is a novel orally active inhibitor (IC50=0.13 nM) of c-MET kinase.
DC9389	INCB3344	INCB3344 is a novel, potent and selective small molecule antagonist of the mouse CCR2 receptor; inhibits the binding of CCL2 to mouse monocytes with nanomolar potency (IC50 = 10 nM).
DC7429	INCB 8761 Featured	INCB8761(PF-4136309) is a potent, Selective, and orally bioavailable CCR2 antagonist.
DC11311	Incensole	Incensole is a diterpene originally isolated from frankincense produced by B. carterii.It inhibits degradation of inhibitor of NF-κB (IκBα) in a concentration-dependent manner in TNF-α-stimulated HeLa cells when used at concentrations ranging from 60 to 1

Products

Customized Consultation X

Your information is safe with us. * Required Fields.