| DC8132 |
TAPI-0 (TNF-α processing inhibitor-0) |
Inhibits TNF-α processing. Also a general matrix metalloprotease and TACE inhibitor. |
|
| DC7171 |
INK-128(Sapanisertib)
Featured
|
INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms. |
|
| DC7873 |
INK-055 (PI3Kγ inhibitor 1) |
INK055 is a dual PI3Kg/d inhibitor. |
|
| DC23238 |
INO-1001 |
INO-1001 is a potent, selective poly(ADP-ribose) polymerase (PARP) with IC50 of <50 nM in CHO cells. |
|
| DC20417 |
iNOS inhibitor 12 |
iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS.. |
|
| DC10555 |
inS3-54A18
Featured
|
inS3-54A18 is a potent STAT3 inhibitor, with anti-cancer properties. |
|
| DC12101 |
Insulin levels modulator |
Insulin levels modulator could be used to treat diabetes. |
|
| DC7430 |
Obeticholic acid (INT-747)
Featured
|
INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity. |
|
| DC22513 |
INT-767 |
INT-767 is a potent, selective, dual farnesoid X receptor (FXR) and TGR5 agonist with EC50 of 30 and 630 nM, respectively. |
|
| DC12106 |
Interferon receptor agonist |
Interferon receptor agonist is an interferonm (IFN) receptor agonist. |
|
| DC8328 |
IRAK-1/4 Inhibitor
Featured
|
Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor is a benzimidazole compound that acts as a cell-permeable, potent selective inhibitor of IL-1 kinases. |
|
| DCAPI1381 |
Inulin |
Inulin |
|
| DC11494 |
INX-08189 |
INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
|
| DC12160 |
Iodipamide (Adipiodone) |
Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. |
|
| DC20420 |
Ionomycin calcium salt |
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. |
|
| DC20419 |
Ionomycin |
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus. |
|
| DC8124 |
ETH 2120(Sodium ionophore III)
Featured
|
Ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc. with a solvent polymeric membrane electrode. |
|
| DC9564 |
Iopamidol |
Iopamidol is a nonionic, low-osmolar iodinated contrast agent.
|
|
| DC7172 |
IOWH-032 |
iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays. |
|
| DC5070 |
IOX2
Featured
|
IOX 2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). IOX 2 displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases. |
|
| DC7614 |
IOX1
Featured
|
IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. |
|
| DC10825 |
IOX4
Featured
|
IOX4 is a potent inhibitor of PHD2 (IC50 = 1.6 nM). |
|
| DC21756 |
IP6K1 inhibitor TNP
Featured
|
IP6K1 inhibitor TNP is a potent, selective inositol hexakisphosphate kinase IP6K with IC50 of 0.47 uM (IP6K1), does not inhibit either human or yeast Vip/PPIP5K. |
|
| DC9575 |
IPA-3 |
IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).
|
|
| DC5072 |
Duvelisib (IPI-145, INK1197)
Featured
|
IPI-145 is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. |
|
| DC9829 |
IPI-549
Featured
|
IPI-549 is an orally administered immuno-oncology development candidate that selectively inhibits PI3K-gamma. |
|
| DC12599 |
IPI-9119 |
IPI-9119 (IPI9119) is a potent, selective, and irreversible inhibitor of fatty acid synthase (FASN) with IC50 of 0.3 nM in biochemical assays. |
|
| DC20667 |
Ipidacrine hydrochloride hydrate |
Ipidacrine hydrochloride hydrate is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
|
| DC20666 |
Ipidacrine hydrochloride |
Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
|
| DCAPI1573 |
Ipragliflozin (ASP1941)
Featured
|
Ipragliflozin (ASP1941) is a Novel Selective Sodium-Dependent Glucose Co-Transporter 2 Inhibitor, on Urinary Glucose Excretion in Healthy Subjects |
|
