| DCAPI1117 |
Ipratropium bromide |
Ipratropium bromide |
|
| DC10295 |
IPSU
Featured
|
IPSU is a selective, orally available and brain penetrant OX2R antagonist with a pKi of 7.85. |
|
| DC9952 |
IQ-1
Featured
|
IQ-1 has many functions such as decreasing Wnt-stimulated phosphorylation, maintaining the pluripotency of murine ESCs, preventing PP2A/Nkd interaction and so on. |
|
| DC9694 |
IQ-1S
Featured
|
IQ-1S is a selective JNK3 inhibitor (IC50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). |
|
| DC23614 |
IQM-266(IQM 266;IQM266) |
IQM-266 (IQM266) is a DREAM (Downstream Regulatory Element Antagonist Modulator) ligand (Kd=4.63 uM), inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner. |
|
| DC21151 |
IR415 |
IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease. |
|
| DC9491 |
IRAK inhibitor 1
Featured
|
IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. |
|
| DC9492 |
IRAK inhibitor 2 |
IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . |
|
| DC9493 |
IRAK inhibitor 6 |
IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor . |
|
| DC10584 |
IRAK4-IN-1
Featured
|
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM. |
|
| DC23594 |
Irampanel |
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
|
| DC23566 |
Irampanel hydrochloride |
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
|
| DC7173 |
Irbesartan
Featured
|
Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM. |
|
| DC8771 |
Tucatinib (Irbinitinib,ARRY-380)
Featured
|
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR. |
|
| DC22411 |
Irdabisant hydrochloride |
Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
|
| DC22419 |
Irdabisant |
Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
|
| DC20422 |
IRE1α-IN-3 |
IRE1α-IN-3 is a novel, potent IRE1α RNase inhibitor with EC50 of 0.82 uM. |
|
| DC23051 |
Irigenin
Featured
|
Irigenin, an α-glucosidase inhibitor, which has anti-inflammatory, anti-cancer, and anti-metastatic effects. Irigenin can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable |
|
| DC4180 |
Irinotecan Hydrochloride
Featured
|
Irinotecan hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. |
|
| DC4153 |
Irinotecan hydrochloride trihydrate |
Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. |
|
| DC8934 |
Irinotecan
Featured
|
Irinotecan(CPT-11) prevents DNA from unwinding by inhibition of topoisomerase 1. |
|
| DC10866 |
Irosustat（STX64）
Featured
|
Irosustat（STX64） is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity. |
|
| DCAPI1578 |
Irsogladine maleate |
Irsogladine maleate is a selective PDE4 inhibitor that facilitates gap junction intercellular communication through muscarinic acetylcholine receptor binding. It is a potent inhibitor of angiogenesis in wild-type and plasminogen activator-deficient mice. |
|
| DC22097 |
IS-741 |
IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).. |
|
| DC10340 |
ISA-2011B |
ISA-2011B is a PIP5Kα inhibitor with promising anticancer effects . |
|
| DC23284 |
ISA27 |
ISA27 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo. |
|
| DC9891 |
Isatin |
Isatin is an endogenous MAO inhibitor. |
|
| DC7609 |
Isatoribine |
Isatoribine is a selective agonist of TLR7 |
|
| DC8120 |
Isavuconazole |
Isavuconazole(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557, exhibits MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata. |
|
| DC11341 |
Isavuconazonium (sulfate) |
Isavuconazonium is a water-soluble prodrug form of the azole antifungal isavuconazole (ISA). |
|
