| DCAPI1010 |
Peramivir Trihydrate
Featured
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Peramivir, also known as BCX1812 and RWJ 270201, is an antiviral drug for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. Peramivir was approved to treat influenza infection in adults. |
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| DC7226 |
Perampanel(E2007）
Featured
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Perampanel(E2007; ER 155055-90) is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical trials. |
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| DC20495 |
Perhexiline |
Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
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| DC21821 |
Perhexiline maleate
Featured
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Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
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| DC2021 |
Perifosine (KRX-0401)
Featured
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Perifosine (KRX-0401) is a novel Akt inhibitor with IC50 of 4.7 μM. |
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| DC9143 |
Perindopril erbumine |
Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease. |
|
| DC12139 |
Perisesaccharide B |
Perisesaccharide B is an oligosaccharide isolated from the root barks of Periploca sepium. |
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| DC12137 |
Perisesaccharide C |
Perisesaccharide C is an oligosaccharide isolated from the root barks of Periploca sepium. |
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| DC20708 |
Perlapine |
Perlapine (AW-14233. |
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| DC12059 |
Pertussis Toxin
Featured
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Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. |
|
| DC12207 |
Petroselinic acid |
Petroselinic acid, a positional isomer of oleic acid, is isolated from the vegetable oil of Coriandrum sativum fruits. |
|
| DC12192 |
PF 03709270 (ulopenem etzadroxil) |
PF 03709270 is an orally available ester prodrug form of sulopenem, with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. |
|
| DC10356 |
PF 03716556 |
PF 03716556 is a potent, and selective acid pump (H+,K+ ATPase) antagonist, with pIC50 value of 6.009. |
|
| DC22930 |
PF-4878691 (3M-852A)
Featured
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PF 04878691 (PF 4878691, S 32865, 852A, 3M 001) is a selective TLR7 agonist that potently induces IFN-α and IFN-regulated proteins from human PBMC. |
|
| DC10529 |
PF 05089771
Featured
|
PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM. |
|
| DC10496 |
PF06260933
Featured
|
PF 06260933 is a potent and selective MAP4K4 inhibitor (IC50 value 3.7 nM for MAP4K4 a.k.a. HGK or ZC1) with suitable PK properties in mouse to be used as a tool in an in vivo model of diabetes, vascular inflammation and atherosclerosis. |
|
| DC7691 |
PF 1022A
Featured
|
PF 1022A is a N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties; acts as an ionophore. |
|
| DC8259 |
PF0477736
Featured
|
PF 477736 is a CHK inhitor with Ki values of 0.49 and 47 nM for Chk1 and Chk2 respectively. A proprietary compound targeting cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiation activity |
|
| DC8147 |
PF 4800567 |
PF 4800567 is a selective casein kinase 1ε inhibitor; displays 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively). |
|
| DC21516 |
PF 5212372 |
PF 5212372 (PLA-950, ZPL-521, ZPL 5212372) is a potent, selective inhibitor of cPLA2 (cytosolic phospholipase A2α) with IC50 of 7 nM. |
|
| DC4106 |
PF573228
Featured
|
PF 573228 is a inhibitor of FAK with IC50 of 4 nM. |
|
| DC21477 |
PF 6260933 dihydrochloride
Featured
|
PF 6260933 is a potent, selective and orally bioavailable MAP4K4 inhibitor with kinase IC50 of 3.7 nM, cell IC50 of 160 nM. |
|
| DC2086 |
PF-670462
Featured
|
PF 670462 is a selective casein kinase, CK1ε and CK1δ inhibitor which also shows potency against 42 other kinases. |
|
| DC20027 |
PF 750
Featured
|
PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile. |
|
| DC11664 |
PF-00446687 hydrochloride |
PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
|
| DC11665 |
PF-00446687 |
PF-00446687(PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
|
| DC3168 |
PF-562271 PHSO3H SALT
Featured
|
PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively. |
|
| DC21500 |
PF-00610355 |
PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM. |
|
| DC10038 |
PF-01247324
Featured
|
PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain. |
|
| DC21495 |
PF-02413873 |
PF-02413873 (PF-2413873) is a potent, selective, fully competitive, and orally active progesterone receptor (PR) antagonist with Ki of 9.7 nM. |
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