DC23192 |
Rhosin hydrochloride
Featured
|
Rhosin (G04) is a potent, specific RhoA subfamily Rho GTPases inhibitor that specifically binds to RhoA to inhibit GEF reaction of RhoA with Kd of 0.4 uM, does not interact with Cdc42 or Rac1, nor the LARG. |
|
DC9881 |
RHPS4
Featured
|
RHPS4 is a potent inhibitor of Telomerase at submicromolar. |
|
DC7264 |
RI-1
Featured
|
RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM. |
|
DC8226 |
RI-2
Featured
|
RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells. |
|
DCAPI1165 |
Ribavirin (Copegus)
Featured
|
Ribavirin is a guanosine analog with antiviral properties against DNA and RNA viruses, including respiratory syncytial virus, hepatitis C, and influenza. |
|
DC24015 |
Ribocil
Featured
|
Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB. |
|
DC12237 |
Riboflavine phosphate (Riboflavine 5'-phosphate) |
Riboflavine phosphate is a very effective NAD+-recycling agent. |
|
DCAPI1325 |
Rifabutin (Mycobutin) |
Rifabutin (Mycobutin) |
|
DCAPI1283 |
Rifapentine (Priftin) |
Rifapentine (Priftin) |
|
DC23909 |
Rifaximin |
Rifaximin is an oral, semi-synthetic antibiotic derived from Rifamycin SV with antibacterial activity, interferes with transcription by binding to the β-subunit of bacterial RNA polymerase. |
|
DCAPI1446 |
rifomycins |
rifomycins |
|
DC7265 |
Rigosertib
Featured
|
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM; shows 30-fold greater selectivity against PLK2 and no activity to PLK3. |
|
DC24085 |
Rigosertib sodium
Featured
|
Rigosertib sodium (ON 01910.Na) is a potent, non-ATP-competitive PLK1 inhibitor (IC50=9-10 nM), selectively induces mitotic G2/M arrest and apoptosis in cancer cells. |
|
DC7266 |
Rilpivirine(R 278474, TMC 278)
Featured
|
Rilpivirine(R 278474, TMC 278) is a type of anti-HIV medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
|
DC8985 |
Riluzole
Featured
|
Riluzole is a glutamate antagonist used as an anticonvulsant and to prolong the survival of patients with amyotrophic lateral sclerosis. |
|
DCAPI1057 |
Rimantadine (Flumadine) |
Rimantadine (Flumadine) |
|
DC12800 |
BMS-927711(Rimegepant)
Featured
|
Rimegepant (BMS-927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM. |
|
DC22089 |
Rimeporide (EMD-87580) |
Rimeporide (EMD87580) is a potent, selective sodium hydrogen exchanger NHE1 inhibitor, show promise as potential therapeutic agents for the treatment of heart failure.. |
|
DC9383 |
Rimonabant (Hydrochloride)
Featured
|
Rimonabant Hcl(SR141716A) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM.
|
|
DC8876 |
Rimonabant(SR141716)
Featured
|
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM. |
|
DC7267 |
Riociguat (BAY 63-2521)
Featured
|
Riociguat (BAY 63-2521) is a stimulator of soluble guanylate cyclase (sGC). |
|
DC20535 |
RIP1-IN-22 |
RIP1-IN-22 is a highly potent, orally available, and brain-penetrating RIP1 kinase inhibitor with pKi of 9.04. |
|
DC10389 |
RIPA-56
Featured
|
RIPA-56 is a highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1) with an IC50 of 13 nM. |
|
DC21945 |
RIPGBM |
RIPGBM is a cell type-selective, small molecule inducer of apoptosis in GBM cancer stem cells (CSCs) with EC50 of 220 nM (GBM 1 cells). |
|
DC20536 |
RIPK2 inhibitor 1 |
RIPK2 inhibitor 1 is a novel potent, selective RIPK2 inhibitor with IC50 of 5-10 nM. |
|
DC21946 |
RIPK2 inhibitor OD36 |
RIPK2 inhibitor OD36 is a potent, specific, ATP-competitive inhibitor of RIPK2 with IC50 of 5.3 nM, inhibits Tyr and Ser/Thr-directed activities of RIPK2. |
|
DC21563 |
Risdiplam
Featured
|
Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA). |
|
DC9049 |
Risedronate Sodium |
Risedronate sodium is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption. |
|
DCAPI1012 |
Risedronic acid (Actonel) |
Risedronic acid (Actonel) |
|
DC23619 |
Rislenemdaz hydrochloride |
Rislenemdaz (MK 0657. |
|