DC23576 |
Rislenemdaz mesylate |
Rislenemdaz (MK 0657. |
|
DC7268 |
Risperidone(R 64 766) |
Risperidone(R 64 766) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM). |
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DC1064 |
RITA (NSC652287)
Featured
|
RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells. |
|
DC9475 |
Ritonavir
Featured
|
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS,showed potent activity against COVID-19(SARS-COV-2) . |
|
DC5108 |
BAY 59-7939 (Rivaroxaban)
Featured
|
Rivaroxaban (Xarelto; BAY 59-7939) is a novel, oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. |
|
DCAPI1435 |
Rivastigmine tartrate |
Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and Parkinson's disease. |
|
DC21053 |
Rivipansel sodium |
Rivipansel sodium (GMI-1070, PF-06460031) is a novel small molecule glycomimetic pan-Selectin antagonist with IC50 of 4.3 uM, 423 uM and 337 uM for E-selectin, P-selectin and L-selectin, respectively. |
|
DCAPI1466 |
Rizatriptan Benzoate |
Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine. |
|
DC23185 |
RJR-2403 oxalate |
RJR-2403 (Rivanicline, Metanicotine) is a potent, selective neuronal nicotinic ACh (nAChR) agonist with high affinity to rat brain cortex (Ki=26 nM), does not significantly activate muscle type nAChRs or muscarinic receptors. |
|
DC23197 |
RJR-2403 |
RJR-2403 (Rivanicline, Metanicotine) is a potent, selective neuronal nicotinic ACh (nAChR) agonist with high affinity to rat brain cortex (Ki=26 nM), does not significantly activate muscle type nAChRs or muscarinic receptors. |
|
DC12481 |
RK-20449 |
RK-20449 (RK20449) is a potent, small molecule inhibitor of hematopoietic cell kinase (HCK) with IC50 of 0.43 nM. |
|
DC12372 |
RK-24466
Featured
|
RK-24466 (KIN 001-51) is a potent and selective Lck inhibitor; inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively. |
|
DC12436 |
RK-287107
Featured
|
RK-287107 (RK287107) is a novel potent, tankyrase-specific inhibitor with IC50 of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively, shows no activity against PARP-1. |
|
DC9761 |
RK-33
Featured
|
RK-33 is a novel DDX3 inhibitor for lung cancer therapy. |
|
DC8831 |
RKI-1313
Featured
|
RKI-1313 is the negative control for RKI-1447 which is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer |
|
DC7269 |
RKI-1447
Featured
|
RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2. |
|
DC12051 |
RMC-4550
Featured
|
RMC-4550 (RMC4550) is a potent, selective, allosteric inhibitor of SHP2 with IC50 of 0.58 nM (full-length SHP2 enzyme), suppresses pERK signaling in Calu-1 cells with IC50 of 7 nM. |
|
DC7636 |
RN-1 Hydrochloride
Featured
|
RN-1 is an inhibitor of lysine specific demethylase 1 (LSD1); exhibits selectivity for LSD1 over monoamine oxidase (MAO)-A and MAO-B (IC50 values are 70 nM, 0.51 and 2.79 μM respectively. |
|
DC11325 |
RN-1734
Featured
|
RN-1734 is a transient receptor potential vanilloid 4 (TRPV4) antagonist, blocking calcium influx induced by the TRPV4 agonist 4α-phorbol 12,13-didecanoate with IC50 values of 2.3, 5.9, and 3.2 µM for human, mouse, and rat TRPV4, respectively. |
|
DC10450 |
RN-18
Featured
|
RN-18 is a selective inhibitor of virion infectivity factor (Vif) APOBEC interactions and HIV-1 replication. |
|
DC5146 |
RN486
Featured
|
RN-486 is a Bruton's tyrosine kinase (Btk) inhibitor. |
|
DC23023 |
RNase L-IN-2 |
RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM. |
|
DC22638 |
RNPA1000 |
RNPA1000 is a potent, specific small molecule inhibitor of S. aureus RnpA RNA degradation activity (IC50=100-125 uM), limits S. aureus mRNA turnover and growth. |
|
DC21569 |
RNPA2000 |
RNPA2000 is a small-molecule inhibitor of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing (IC50=130 uM). |
|
DC23852 |
Ro 08-2750 |
Ro 08-2750 (Ro 082750) is a potent, selective, non-peptide nerve growth factor (NGF) inhibitor that binds to NGF dimer with Kd of 1 uM. |
|
DC23321 |
RO 2443 |
RO 2443 is a potent, dual MDM2/MDMX antagonist that inhibits both MDM2 (IC50=33 nM) and MDMX (IC50=41 nM) binding to p53, but poor water solubility does not allow for a meaningful assessment of its cellular activity.. |
|
DC9851 |
Ro 25-6981 |
Ro 25-6981 is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. |
|
DC9852 |
Ro 25-6981 maleate
Featured
|
Ro 25-6981 is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. |
|
DC22215 |
RO 27-3225
Featured
|
RO 27-3225 (RO27-3225, RO 273225) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM, >30-fold selectivity over MC3R. |
|
DC9454 |
Ro 28-1675 |
Ro 28-1675 (Ro 0281675) is a potent allosteric GK activator with a SC1.5 value of 0.24± 0.0019 uM. |
|