| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9329 | (±)-Huperzine A | Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). |
|
| DC8166 | Molidustat(BAY 85-3934) Featured | Hypoxia-inducible factor prolyl hydroxylase inhibitor |
|
| DC11262 | IACS-010759 Featured | IACS-010759 (IACS010759) is a small molecule inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targets complex I of the mitochondrial electron transport chain. |
|
| DC10174 | Iberdomide Featured | Iberdomide (CC-220) is a cereblon modulator in clinical development for systemic lupus erythematosis. Iberdomide exhibits an IC50 of 60 nM in TR-FRET cereblon binding assay. |
|
| DC10007 | Ibiglustat(Genz-682452） Featured | Ibiglustat (Genz-682452,SAR402671), is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. |
|
| DC8983 | Ibudilast Featured | Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma,ibudilast (MN-166) is tested to treat acute respiratory distress syndrome (ARDS) associated with Covid-19. |
|
| DC8965 | Ibuprofen | Ibuprofen (Motrin) is an anti-inflammatory inhibitor targeting COX-1 and COX-2, of which is used for pain relief, fever reduction and for reducing swelling. |
|
| DC7020 | Ibutamoren mesylate Featured | Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. |
|
| DC11303 | CT7001 hydrochloride Featured | ICEC0942 is a selective CDK7 inhibitor, with IC50s of 41 nM and 578 nM for CDK7/CycH/MAT1 and CDK2/cycE1, respectively. |
|
| DC3130 | ICG-001 Featured | ICG-001 is a small-molecule antagonist of b-catenin/TCF-mediated transcription (IC50 = 3 uM) and specifically downregulates the expression of a subset of b-catenin/TCF-responsive genes. ICG-001 binds specifically to cyclic AMP response element-binding pro |
|
| DC8111 | Idarubicin Hydrochloride Featured | Idarubicin Hcl is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. |
.gif)
|
| DC10538 | IDH-305 Featured | IDH305 is an inhibitor of the citric acid cycle enzyme isocitrate dehydrogenase [NADP] cytoplasmic (isocitrate dehydrogenase 1; IDH1) with mutations at residue R132 (IDH1(R132)), with potential antineoplastic activity. |
|
| DC10098 | IDO-IN-1 Featured | IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM). |
|
| DC9014 | Ifosfamide | Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. |
|
| DC8872 | Iguratimod Featured | Iguratimod is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesic and antipyretic activity. |
|
| DC10205 | Ilaprazole Featured | Ilaprazole (IY-81149) is a proton pump inhibitor; inhibits H+/K+-ATPase with an IC50 of 6.0 μM. |
|
| DCAPI1055 | Iloperidone (Fanapt) | Iloperidone (Fanapt) |
|
| DC4181 | Imatinib mesylate Featured | Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. |
|
| DC10406 | Imisopasem manganese | Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD. |
|
| DC10918 | INCB053914 | INCB053914 (INCB-053914) is a novel potent, and selective ATP-competitive, pan-PIM kinase inhibitor with IC50 of 0.24/30.0/0.12 nM for PIM1/2/3, respectively. |
|
| DC7167 | Capmatinib(INCB28060) Featured | INCB28060 is a novel orally active inhibitor (IC50=0.13 nM) of c-MET kinase. |
|
| DC9389 | INCB3344 | INCB3344 is a novel, potent and selective small molecule antagonist of the mouse CCR2 receptor; inhibits the binding of CCL2 to mouse monocytes with nanomolar potency (IC50 = 10 nM). |
|
| DC7429 | INCB 8761 Featured | INCB8761(PF-4136309) is a potent, Selective, and orally bioavailable CCR2 antagonist. |
|
| DC4137 | Indiplon Featured | Indiplon is a novel sedative-hypnotic recently approved for the treatment of insomnia. |
|
| DCAPI1506 | Mitiglinide Calcium | Inhibitor of ATP-sensitive K+ channel activity in MIN 6 cells. Has also been shown to bind sulfonylurea receptors as well. |
|
| DC7171 | INK-128(Sapanisertib) Featured | INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms. |
|
| DC7430 | Obeticholic acid (INT-747) Featured | INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity. |
|
| DC11494 | INX-08189 | INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
|
| DC7172 | IOWH-032 | iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays. |
|
| DC5072 | Duvelisib (IPI-145, INK1197) Featured | IPI-145 is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. |
|
