Cat. No. | Product name | CAS No. |
DC9308 |
Doravirine (MK-1439)
Featured
Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor. |
1338225-97-0 |
DC4157 |
Dovitinib (TKI258, CHIR258)
Featured
Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively. |
405169-16-6 |
DC10313 |
Dovitinib lactate
Dovitinib(CHIR-258; TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM. |
692737-80-7 |
DCAPI1241 |
Doxercalciferol (Hectorol)
Featured
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease. |
54573-75-0 |
DCAPI1457 |
Dronedarone Hydrochloride
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium and sodium and is a calcium channel protein inhibitor. |
141625-93-6 |
DC11726 |
DS-3032b
Featured
DS-3032b is a potent, selective, orally available MDM2-p53 inhibitor with potential antineoplastic activity. |
1398568-47-2 |
DC11233 |
DS-8500a
DS-8500a (DS8500a) is a novel potent, selective, orally available GPR119 agonist with EC50 of 51.5 nM in human GPR119-expressing CHO-K1 cells, displays no significant effect on 66 receptors, channels, or transporters. |
1371591-51-3 |
DC11409 |
DSM265
Featured
DSM265 is a PfDHODH inhibitor with an IC50 of 8.9 nM. DSM265 can also inhibit the growth of P. falciparum 3D7 parasites with an EC50 of 4.3 nM. |
1282041-94-4 |
DC8277 |
E-2012
Featured
E 2012 is a potent γ-secretase modulator. |
870843-42-8 |
DC8404 |
E3330
Featured
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. |
136164-66-4 |
DC7128 |
Lucitanib(E3810)
Featured
E-3810 is a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. |
1058137-23-7 |
DC9595 |
E-4031
E-4031 is a benzenesulfonamide antiarrhythmic agent; blocks the ATP-sensitive potassium channel. |
113559-13-0 |
DC8533 |
E5555 hydrobromide
E5555 shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC values of 0.064 and 0.031 μM respectively. |
474550-69-1 |
DC10141 |
E6005
Featured
E6005 potently and selectively inhibited human PDE4 activity with an IC50 of 2.8 nM and suppressed the production of various cytokines from human lymphocytes and monocytes with IC50 values ranging from 0.49 to 3.1 nM. |
947620-48-6 |
DC8485 |
E-64d(Aloxistatin)
Featured
E-64D is an inhibitor of cathepsins B and L; also thought to inhibit calpain,showed a potent activity for COVID-19(SARS-COV-2)with EC50: MERS-COV(1.275),SARS-COV(0.760) |
88321-09-9 |
DC10563 |
E-7046
Featured
E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities. |
1369489-71-3 |
DC5065 |
Golvatinib (E7050)
Featured
E-7050 is hepatocyte growth factor receptors (HGFR). |
928037-13-2 |
DC7116 |
E7080 (Lenvatinib)
Featured
E7080 (Lenvatinib; Vargatef) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. |
417716-92-8 |
DC11062 |
E7107
E7107 (E-7107) is a derivative of pladienolide that targets the SF3b subunit of the spliceosome, shows significant antitumor activity in vitro and in vivo. |
630100-90-2 |
DC9983 |
E-7449
Featured
E7449 is an orally bioavailable, potent, small molecule inhibitor of PARP1 and PARP2; enhances the efficacy of radiotherapy and chemotherapy and has potent single agent anticancer activity in BRCA-deficient tumors. |
1140964-99-3 |
DCAPI1441 |
Seocalcitol
EB1089 is an analog of 1,25 dihydroxyvitamin D which acts as a vitamin D receptor (VDR). EB1089 is noted to reverse hypercalcemia and is a potent inhibitor of PTH-rP (parathyroid hormone-related peptide, PTHRP) in vitro. In studies utilizing a squamous ca |
134404-52-7 |
DC10939 |
Edasalonexent
Edasalonexent (CAT-1004) is a bifunctional, orally administered small molecule that covalently links 2 compounds known to inhibit NF‐κB, salicylic acid and docosahexaenoic acid (DHA). |
1204317-86-1 |