Cat. No. | Product name | CAS No. |
DC1054 |
GDC0941(Pictilisib)
Featured
GDC-0941 is a potent inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ with IC50 of 3 nM, 33 nM, 3 nM and 75 nM, respectively. |
957054-30-7 |
DC4177 |
Cobimetinib(GDC-0973; XL518)
Featured
GDC-0973 is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase, also known as MEK, a serine/threonine kinase that is a component of the RAS/RAF/MEK/ERK pathway. |
934660-93-2 |
DC5081 |
Apitolisib
Featured
GDC-0980 (RG7422) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM, respectively. Also a mTOR inhibitor with Ki of 17 nM, and highly selective versus others PIKK family kinases. |
1032754-93-0 |
DC10721 |
Gefapixant(AF-219,MK-7264)
Featured
Gefapixant(AF-219,MK-7264) is novel P2X3 receptor antagonist. |
1015787-98-0 |
DC2103 |
Gefitinib (ZD1839)
Featured
Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. |
184475-35-2 |
DC2107 |
Gemcitabine HCl (Gemzar,LY188011)
Featured
Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(1.216), SARS-COV(4.9 |
122111-03-9 |
DC2108 |
Gemcitabine free base
Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites. |
95058-81-4 |
DC12342 |
Gemilukast (ONO-6950)
Gemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively. |
1232861-58-3 |
DC10161 |
Gepotidacin
Featured
Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. |
1075236-89-3 |
DC10490 |
GIBH-130
Featured
GIBH-130 is a novel inhibitor of neuroinflammation effective in Alzheimer’s disease models. |
1252608-59-5 |
DC8946 |
Gimeracil
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which degrades pyrimidine including 5-fluorouracil in the blood; inhibits homologous recombination. |
103766-25-2 |
DC8118 |
GKT137831(Setanaxib)
Featured
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 140±40 nM and 110±30 nM; a potent inhibitor of fibrosis and hepatocyte apoptosis. |
1218942-37-0 |
DC10818 |
ABT-493(Glecaprevir)
Featured
Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. |
1365970-03-1 |
DC11803 |
GLPG-1690(Ziritaxestat)
Featured
GLPG-1690 is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM. |
1628260-79-6 |
DC10753 |
GLPG-1837(ABBV-974)
Featured
GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator. |
1654725-02-6 |
DC11678 |
GLPG-2222
GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM. |
1918143-53-9 |
DC10003 |
PF-06291874(glucagon receptor antagonists-4)
Featured
glucagon receptor antagonists-4 is a highly potent glucagon receptor antagonist. |
1393124-08-7 |
DC11543 |
Glumetinib
Featured
Glumetinib (SCC 244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM. |
1642581-63-2 |
DC8779 |
Glycopyrrolate
Featured
Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
596-51-0 |
DC7419 |
GNE-7915
Featured
GNE-7915 is a highly potent, selective, and brain-penetrable LRRK2 small molecule inhibitor with IC50 of 9 nM in cellular LRRK2 assay; > 100 fold selectivity against a panel of 187 kianses(Ki). |
1351761-44-8 |
DC7137 |
Filgotinib(GLPG0634)
Featured
GPLG0634 is a novel inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively. |
1206161-97-8 |
DC11090 |
GR3027
Featured
GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC. |
2089238-18-4 |