Cat. No. | Product name | CAS No. |
DC8174 |
Pexmetinib(ARRY-614)
Featured
Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38α and p38β, respectively, and can be used in the research of acute myeloid leukemia. |
945614-12-0 |
DC6917 |
Vonoprazan
Featured
For the detailed information of Vonoprazan, the solubility of Vonoprazan in water, the solubility of Vonoprazan in DMSO, the solubility of Vonoprazan in PBS buffer, the animal experiment (test) of Vonoprazan, the cell expriment (test) of Vonoprazan, the in vivo, in vitro and clinical trial test of Vonoprazan, the EC50, IC50,and affinity,of Vonoprazan, For the detailed information of Vonoprazan, the solubility of Vonoprazan in water, the solubility of Vonoprazan in DMSO, the solubility of Vonoprazan in PBS buffer, the animal experiment (test) of Vonoprazan, the cell expriment (test) of Vonoprazan, the in vivo, in vitro and clinical trial test of Vonoprazan, the EC50, IC50,and affinity,of Vonoprazan, Please contact DC Chemicals.. |
881681-00-1 |
DC7342 |
Foretinib(XL880)
Featured
Foretinib (GSK1363089; XL880; EXEL-2880; GSK089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. |
849217-64-7 |
DC5882 |
Fosbretabulin disodium
Featured
Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis. |
168555-66-6 |
DC7824 |
Fosfluconazole(INN)
Fosfluconazole (INN) is a water-soluble phosphate prodrug of fluconazole |
194798-83-9 |
DC11086 |
Foslinanib
Foslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, induces cancer cell apoptosis and inhibits cancer cell proliferation. |
1256037-60-1 |
DC10947 |
FPL64176
Featured
FPL64176 is a potent L-type Ca++ channel activator with EC50 of 16 nM. |
120934-96-5 |
DC10307 |
Framycetin
Framycetin (Fradiomycin B; Neomycin B) is an aminoglycoside antibiotic. It inhibits hammerhead ribozyme with a Ki of 13.5 μM. |
119-04-0 |
DC7902 |
Fruquintinib (HMPL-013)
Featured
Fruquintinib (HMPL-013) is a novel small molecule compound that selectively inhibits vascular endothelial growth factor receptors (VEGFRs). |
1194506-26-7 |
DC3154 |
Fingolimod HCl(FTY-720)
Featured
FTY720 (Fingolimod, Gilenya) is a S1P antagonist with IC50 of 0.033 nM. |
162359-56-0 |
DC11394 |
Fulacimstat(BAY 1142524)
Featured
Fulacimstat(BAY 1142524) is a small molecule chymase inhibitor. |
1488354-15-9 |
DC10501 |
G1T28(Trilaciclib)
Featured
G1T28(Trilaciclib) is a potential first-in-class, short-acting IV CDK4/6 inhibitor being developed to preserve hematopoietic stem cells and enhance immune system function during chemotherapy. |
1374743-00-6 |
DC9859 |
GAL-021
Featured
GAL-021 is a new intravenous BKCa-channel blocker. |
1380341-99-0 |
DC8929 |
Garenoxacin
Garenoxacin is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections. |
194804-75-6 |
DC8893 |
Garenoxacin Mesylate hydrate
Garenoxacin mesylate hydrate is a novel oral des-fluoro(6) quinolone with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. |
223652-90-2 |
DC10474 |
GBT-440(Voxelotor)
Featured
GBT-440(Voxelotor) is a novel small molecule hemoglobin modifier which increases hemoglobin oxygen affinity. |
1446321-46-5 |
DC10153 |
GDC-0077
Featured
GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity. GDC-0077 is extracted from patent WO 2017001645 A1, formula I. |
2060571-02-8 |
DC9708 |
Paxalisib (GDC-0084)
Featured
GDC-0084 (RG7666), is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. |
1382979-44-3 |
DC10485 |
GDC0575(ARRY-575,RG7441)
Featured
GDC0575(ARRY-575,RG7441)is a small molecule inhibitor of cell cycle checkpoint kinase 1 (Chk1), with potential chemosensitization activity. |
1196541-47-5 |
DC9942 |
GDC-0853(RG7845)
Featured
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. |
1434048-34-6 |
DC3102 |
GDC-0879
GDC-0879 is a novel potent, selective B-Raf inhibitor for B-RafV600E with IC50 of 0.13 nM. |
905281-76-7 |
DC9592 |
GDC-0941 (dimethanesulfonate)
GDC-0941 2 MeSO3H salt is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). |
957054-33-0 |