| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC7459 | LY500307 | LY500307 is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2. |
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| DC10560 | MAK683 Featured | MAK683 is a novel PRC2/EED inhibitor. |
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| DC9190 | Manidipine Dihydrochlorid | Manidipine 2Hcl (CV-4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM. |
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| DC11315 | Manidipine(CV-4093) | Manidipine is a dihydropyridine L- and T-type calcium channel blocker. |
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| DC8031 | Marimastat | Marimastat is a broad spectrum MMP inhibitor and selective TACE inhibitor |
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| DC7460 | Masitinib Featured | Masitinib is a broad coronavirus 3CL inhibitor that effectively blocks replication of SARS-CoV-2. Science 20 Jul 2021: eabg5827 DOI: 10.1126/science.abg5827 |
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| DC11524 | Mavacamten（MYK-461） Featured | Mavacamten（MYK-461）is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain. |
|
| DC8378 | Mavatrep(JNJ-39439335) Featured | Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6. |
|
| DC5069 | Enzalutamide (MDV3100) Featured | MDV3100 is an androgen-receptor (AR) antagonist with IC50 of 36 nM. |
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| DC10258 | Mebendazole | Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking g |
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| DC9050 | Melphalan Featured | Melphalan(Sarcolysin; L-PAM) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents; attaches the alkyl group to the guanine base of DNA. |
|
| DC11419 | Merimepodib Featured | Merimepodib(VX-497) is a novel noncompetitive inhibitor of IMPDH (Inosine monophosphate dehydrogenase). |
|
| DC4182 | Temozolomide Featured | Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer. |
|
| DCAPI1146 | Methoxsalen (Oxsoralen) | Methoxsalen (Oxsoralen) |
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| DC9527 | Methylnaltrexone (Bromide) Featured | Methylnaltrexone Bromide is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation. |
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| DC9191 | Metoprolol tartrate | Metoprolol is a cardioselective β1-adrenergic blocking agent. |
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| DC7196 | MGCD0103 (Mocetinostat) Featured | MGCD0103 (Mocetinostat) is a potent HDAC inhibitor with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3, respectively. |
|
| DC9995 | MGL-3196(Resmetirom) Featured | MGL-3196 is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia. |
|
| DC8545 | MI-503 Featured | MI-503 is a highly potent and orally bioavailable small molecule inhibitor of the menin-MLL interaction. |
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| DC8414 | MI-77301 (SAR405838) Featured | MI-77301 (SAR405838) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1. |
|
| DC8928 | Minocycline hydrochloride Featured | Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. |
|
| DC10013 | Mirogabalin Featured | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
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| DC10532 | Mirogabalin besylate Featured | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
|
| DC9836 | Mivebresib(ABBV-075） Featured | Mivebresib is a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. |
|
| DC9011 | Mizoribine Featured | Mizoribine(NSC 289637; HE 69; β-Bredinin) is an immunosuppressive agents (IC50=100 uM) that inhibit the proliferation of lymphocytes selectively, via inhibition of IMPDH. |
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| DC1009 | Laropiprant Featured | MK 0524 is a potent, selective DP1 receptor antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively. |
|
| DC9456 | MK-0354 | MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b. |
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| DC3167 | MK0812 | MK-0812 is chemokine receptor CCR-2 antagonist |
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| DC8041 | MK-0941 Featured | MK-0941 is a novel Glucokinase activator (GKA) |
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| DC9398 | MK-0974 | MK-0974(Telcagepant) is a highly potent, selective, and orally bioavailable CGRP receptor antagonist with Ki values of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors respectively; displays >1500-fold lower affinity for the canine and rat receptors |
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