| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10951 | MPT0E028 | MPT0E028 is a potent HDAC inhibitor that inhibits nuclear HDAC activity with IC50 of 11.1 nM in HeLa cells, 9-30 times more potent than SAHA. |
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| DC3122 | MRK003 | MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma. |
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| DC11273 | Murepavadin (POL7080) Featured | Murepavadin is a novel class of highly specific outer membrane protein targeting antibiotic to treat resistant Pseudomonas infections. |
|
| DC9298 | thiotepa Featured | N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group. |
|
| DC7471 | N6022 Featured | N6022 is a potent, selective, reversible, and efficacious S-Nitrosoglutathione reductase(GSNOR) inhibitor(IC50=10 nM) which is currently undergoing clinical development. |
|
| DC9619 | Nafamostat (mesylate) Featured | Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant,showed highly potent activity against COVID-19(SARS-COV-2). |
|
| DC9787 | NAMI-A | NAMI-A is a ruthenium anticancer agent and a metastasis inhibitor. |
|
| DC8474 | Napabucasin (BBI608) Featured | Napabucasin (BBI608) is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells. |
|
| DC9476 | NBD-556 Featured | NBD-556 is small molecule mimetic of CD4, NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. |
|
| DC9477 | NBD-557 | NBD-557 is a potentially HIV-1 inhibitor. |
|
| DC9770 | NCB-0846 Featured | NCB-0846 is a novel,first-in-class,orally TNIK inhibitor with an IC50 value of 21 nM,that have shown strong anti-tumor efficacy against several cancer models. |
|
| DC10173 | Firsocostat(ND-630,GS-0976) Featured | ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. |
|
| DC10455 | NE-100 Featured | NE100 hydrochloride is a potent and selective σ1 receptor antagonist (Ki = 0.86 nM) that displays > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1, |
|
| DC7472 | Nedocromil | Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma. |
|
| DC10355 | Nelfinavir Featured | Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
|
| DC9474 | Nelfinavir (Mesylate) | Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
|
| DC11247 | Nelonicline Featured | Nelonicline (ABT-126) is a potent, selective α7 nicotinic receptor (nAChR) partial agonist for the treatment of cognitive impairment with schizophrenia.. |
|
| DC11469 | APD125(Nelotanserin) Featured | Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. |
|
| DCAPI1342 | Nepafenac | Nepafenac |
|
| DC5177 | Nepicastat HCl (SYN-117) Featured | Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. |
|
| DC7211 | Neratinib (HKI-272) Featured | Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for HER2 and EGFR, respectively. |
|
| DC11550 | Netazepide | Netazepide (YF476, Sograzepide) is a potent, selective and orally active gastrin/CCK-2 antagonist with IC50 of 0.1 nM. |
|
| DC9019 | Nevirapine | Nevirapine is a potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of HIV-1 infection and AIDS. |
|
| DC9796 | Nicainoprolhe(Nicainoprol) Featured | Nicainoprolhe is an antiarrhythmic agent,a fast-sodiumchannel blocking drug (class Ib), also protected isolated rat hearts against reperfusion arrhythmias. |
|
| DC9170 | Nicardipine hydrochloride | Nicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. |
|
| DC3144 | Nilotinib Featured | Nilotinib (AMN-107, Tasigna) is a Bcr-Abl inhibitor with IC50 less than 30 nM. |
|
| DC7084 | Nintedanib (BIBF 1120) Featured | Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. |
|
| DC8608 | BIBF 1120 esylate Featured | Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. |
|
| DC9108 | Nisoldipine | Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
|
| DC7791 | NITD 609 | NITD 609 is a novel and potent drug candidate for the treatment of uncomplicated malaria |
|
