| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11265 | S49076 (hydrochloride) Featured | S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. |
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| DC10071 | S49076 Featured | S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM. |
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| DC12279 | S55746 hydrochloride (BLC201 (hydrochloride)) | S55746 hydrochloride is a potent, orally active and selective BCL-2 inhibitor, with Kis and Kds of 1.3 nM, 520 nM and 3.9 nM, 186 nM for BCL-2 and BCL-XL, respectively. S55746 hydrochloride has antitumor activity. |
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| DC12163 | S55746 (BLC201) Featured | S55746 (BLC201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BLC201) has antitumor activity with low toxicity[1]. |
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| DC10137 | S63845 Featured | S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor; binds human MCL1 with a Kd of 0.19 nM. |
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| DC4134 | Safinamide | Safinamide (EMD 1195686; FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. |
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| DC8436 | Salmeterol Xinafoate Featured | Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. |
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| DC10444 | Sapacitabine (CYC682) Featured | Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity. |
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| DC7078 | AZD-8931(Sapitinib) Featured | Sapitinib(AZD8931) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM respectively. |
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| DC8627 | Saquinavir Featured | Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. |
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| DC8628 | Saquinavir Mesylate Featured | Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. |
|
| DC8224 | Lifitegrast(SAR 1118) Featured | SAR 1118 is a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist for treating dry eye. |
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| DC10925 | SAR-100842 Featured | SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays. |
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| DC7672 | SAR125844 Featured | SAR125844 is inhibitor of the proto-oncogene c-Met (also known as hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. |
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| DC7276 | Saracatinib (AZD0530) Featured | Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). |
|
| DC12276 | Saridegib (IPI-926; Patidegib) Featured | Saridegib is a potent and specific inhibitor of Smoothened (Smo), a key signaling transmembrane protein in the Hedgehog (Hh) pathway. |
|
| DC9313 | Sarpogrelate (hydrochloride) Featured | Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. |
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| DC8875 | Saxagliptin Featured | Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM. |
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| DC7495 | SB-334867 HCl Featured | SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2. |
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| DC8419 | SB-334867 Featured | SB-334867 is a selective orexin-1 (OX1) receptor antagonist. |
|
| DC9635 | SB-705498 Featured | SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.1. |
|
| DC5137 | SB 743921 Featured | SB743921 is a kinesin spindle protein (KSP) inhibitor with Ki of 0.1 nM, almost no affinity to MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4 and CENP-E. |
|
| DC10729 | SB9200(Inarigivir soproxil) Featured | SB9200(Inarigivir soproxil) is a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants. |
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| DC5024 | MK-8776 (SCH 900776) Featured | SCH 900776 is a selective Chk1 inhibitor with IC50 of 3 nM. It shows 50-fold selectivity against Chk2. Phase 2. |
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| DC9410 | SCH 527123 | SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively. |
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| DC7283 | SCH-772984 Featured | SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively. |
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| DC10700 | Seladelpar Featured | Seladelpar is a selective peroxisome proliferator-activated receptor (SPPAR) -δ receptor agonist. |
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| DC9864 | Azidothymidine (AZT) | Selective reverse transcriptase inhibitor. Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. |
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| DC10193 | Seletalisib Featured | Seletalisib (UCB5857) is potent and selective PI3Kδ inhibitor with an IC50 of 12 nM. |
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| DC7496 | Semagacestat Featured | Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM. |
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