| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCAPI1553 | Pyrimethamine | Pyrimethamine is a potent inhibitor of multi-drug and toxin extrusion transporters. This compound inhibits Mdr-1(Pgp) and thus allows for active drugs to stay within the cell for longer periods of time, increasing their effectiveness by preventing efflux |
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| DC7664 | Quarfloxin (CX-3543) Featured | Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity. |
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| DC5197 | Quizartinib (AC220) Featured | Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 1/2. |
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| DC11138 | Guanabenz acetate | R15A inhibitor. |
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| DC2068 | R547 | R547 is a potent and selective CDK inhibitor with Ki and IC50 of 1-3 nM and 80 nM respectively. |
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| DC9462 | R-7128(Mericitabine) Featured | R-7128(Mericitabine) is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes. |
|
| DC9841 | Fostamatinib(R788) Featured | R788 (Fostamatinib), a prodrug of the active metabolite R406, is a potent Syk inhibitor with IC50 of 41 nM. |
|
| DC1013 | R788 disodium (Fostamatinib) Featured | R935788 (Fostamatinib disodium, R788) is a Syk inhibitor with IC50 of 41 nM. |
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| DC9513 | Radafaxine (hydrochloride) Featured | Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulat |
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| DC5049 | RAF265 (CHIR-265) Featured | RAF265 (CHIR-265) is a highly selective B-Raf and VEGFR2 inhibitor with IC50 of 3-60 nM and EC50 of 30 nM, including B-Raf, C-Raf and mutant B-Raf. |
|
| DC8930 | Rafoxanide | Rafoxanide is a salicylanilide used as an antiparasitic agent. |
|
| DC9479 | Raltegravir (potassium salt) | Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection. |
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| DCAPI1581 | Raltegravir Featured | Raltegravir Salt is a potent human immunodeficiency virus (HIV) integrase inhibitor and a novel anti-AIDS drug. |
|
| DC8940 | Raltitrexed Featured | Raltitrexed(ZD1694), an inhibitor of thymidylate synthase, is an antimetabolite drug used in cancer chemotherapy. |
|
| DC9162 | Ranolazine HCl Featured | Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP). |
|
| DC1048 | Rapamycin (Sirolimus) Featured | Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM. - |
|
| DC8175 | Rapastinel(GLYX-13) Featured | Rapastinel(GLYX-13) is a NMDA receptor partial agonist that acts at the glycine site. |
|
| DC8190 | Ravidasvir hydrochloride (PPI-668) Featured | Ravidasvir(PPI-668) is a NS5A Inhibitor. |
|
| DC7808 | Refametinib (BAY86-9766) Featured | Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively. |
|
| DC9777 | Regorafenib monohydrate（BAY 73-4506） Featured | Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. |
|
| DC1030 | Regorafenib (BAY73-4506,Fluoro-Sorafenib) Featured | Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. |
|
| DC10441 | Relebactam Featured | Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes. |
|
| DC10463 | Repotrectinib(TPX-005) Featured | Repotrectinib(TPX-005) is a multi-target macrocycle inhibitor of anaplastic lymphoma kinase (ALK), c-ros proto-oncogene 1 receptor tyrosine kinase (ROS1), and neurotrophic tyrosine kinase receptor (TRK) |
|
| DC7261 | Resminostat hydrochloride (4SC-201) | Resminostat(RAS2410; 4SC-201) is a potent inhibitor of HDAC1/3/6(IC50=43-72 nM); less potent to HDAC8 with IC50 of 877 nM. |
|
| DC4148 | Retapamulin | Retapamulin is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM. |
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| DC10191 | RG7800 | RG7800 a small molecule SMN2 splicing modifier to enter human clinical trials to treat spinal muscular atrophy. |
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| DC8185 | Verosudil(AR-12286) | Rho-kinase (ROCK) inhibitor |
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| DCAPI1165 | Ribavirin (Copegus) Featured | Ribavirin is a guanosine analog with antiviral properties against DNA and RNA viruses, including respiratory syncytial virus, hepatitis C, and influenza. |
|
| DCAPI1325 | Rifabutin (Mycobutin) | Rifabutin (Mycobutin) |
|
| DC7265 | Rigosertib Featured | Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM; shows 30-fold greater selectivity against PLK2 and no activity to PLK3. |
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