ASC-J9

  Cat. No.:  DC4169  
Chemical Structure
917813-54-8
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More than 5000 active chemicals with high quality for research!
Field of application
ASC-J9, is antitumor agent. ASC-J9 suppresses castration-resistant prostate cancer growth via degradation of full-length and splice variant androgen receptors.
Cas No.: 917813-54-8
Synonyms: ASC J9
SMILES: O=C(/C=C(O)/C=C/C1=CC(OC)=C(OC)C=C1)/C=C/C(C=C2OC)=CC=C2OC
Formula: C23H24O6
M.Wt: 396.43
Purity: 99%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: For the detailed information about the solubility of ASC-J9 in water, the solubility of ASC-J9 in DMSO, the solubility of ASC-J9 in PBS buffer, the animal experiment(test) of ASC-J9, the in vivo,in vitro and clinical trial test of ASC-J9, the cell experiment(test) of ASC-J9, the IC50, EC50 and Affinity of ASC-J9 , please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47757 A4B17 A4B17 is an androgen receptor N-terminal inhibitor for treating androgen-responsive prostate cancer.
DC47094 MK-3984 MK-3984 is a selective androgen receptor modulator (SARM). MK-3984 can be used for the research of muscle wasting associated with cancer.
DC47001 Rezvilutamide Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer.
DC46941 Cl-4AS-1 Cl-4AS-1, a potent steroidal androgen receptor (AR) agonist (IC50 = 12 nM), is also an inhibitor of 5α-reductase types I and II (IC50 = 6 and 10 nM, respectively).
DC45884 Honokiol DCA Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level.
DC45606 CLP-3094 CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). CLP-3094 inhibits AR transcriptional activity (IC50=4 μM). CLP-3094 is a selective, potent GPR142 antagonist.
DC41259 Bromopropylate Bromopropylate is a pesticide with moderate anti-androgenic activities.
DC41093 Apalutamide D4 Apalutamide D4 (ARN-509 D4) is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.
DC40448 Androgen receptor antagonist 1 Androgen receptor antagonist 1 is an orally available full androgen receptor (AR) antagonist with an IC50 of 59 nM. Androgen receptor antagonist 1 (Compound 6) can be used in the synthesis of PROTAC AR degraders, which results 24% and 47 % AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively.
DC40171 (R)-UT-155 (R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer.
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