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SEMBL

  Cat. No.:  DC20544   Featured
Chemical Structure
1443448-82-5
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More than 5000 active chemicals with high quality for research!
Field of application
SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1443448-82-5
Chemical Name: Sembl
Synonyms: SEMBL;2-hydroxy-N-[(3S)-4-methylene-5-oxo-tetrahydrofuran-3-yl]benzamide;(S)-beta-Salicyloylamino-alpha-exo-methylene-gamma-butyrolactone
SMILES: O1C(C(=C([H])[H])[C@@]([H])(C1([H])[H])N([H])C(C1=C([H])C([H])=C([H])C([H])=C1O[H])=O)=O
Formula: C12H11NO4
M.Wt: 233.2200
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65; inhibits LPS-induced NF-κB activation, iNOS expression, and inflammatory cytokine secretions; also inhibits NF-κB and cellular invasion in ovarian carcinoma ES-2 cells; enhances stability in aqueous solution compared with (-)-DHMEQ.
References: References 1. Sidthipong K, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):562-566. View Related Products by Target NF-κB
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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