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Indisulam

  Cat. No.:  DC20984   Featured
Chemical Structure
165668-41-7
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More than 5000 active chemicals with high quality for research!
Field of application
Indisulam (E7070) is a potent sulfonamide-based cell-cycle inhibitor with notable antiproliferative effects. It induces a reduction in the S phase fraction while promoting G1 and/or G2 phase accumulation in various cancer cell lines.
Cas No.: 165668-41-7
Chemical Name: Indisulam
Synonyms: Indisulam;N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide;4-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;1,4-Benzenedisulfonamide,N-(3-chloro-1H-indol-7-yl);E7070;Indisulam (IND);N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;N-(3-chloro-1H-indol-7-yl)-4-sulfamoylbenzenesulfonamide;N1-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide;E-7070;ER-35744;IndisulaM (E7070);IndisulaM (E7070) (ER-35744);N1-(3-Chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;1,4-Benzenedisulfonamide, N-(3-chloro-1H-indol-7-yl)-;E 7070;WJ98J3NM90;N-(3-Chloro-1H-indol-7-yl)benzene-1,4disulfonamide;Indisulam (USAN/INN);N-(3-chl;INDISULAM;CS-0007710;FT-0740093;A904802;EF6;UNII-WJ98J3NM90;INDISULAM [WHO-DD];SB16544;indisulam (e7070);1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;indisulamum;INDISULAM [INN];Indisulam [USAN:INN:BAN];C14H12ClN3O4S2;HY-13650;1,4-BENZENEDISULFONAMIDE, N-(3-CHLORO-1H-INDOL-7-YL);165668-41-7;N(1)-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;INDISULAM [USAN];C73201;Z2724205552;DB06370;1,4-Benzenedisulfonamide, N1-(3-chloro-1H-indol-7-yl)-;NS00068354;s9742;EN300-7378250;CHEMBL77517;N1-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;GTPL7046;AKOS022181456;D04522;BCP06110;AS-69532;BDBM10890;CHEBI:145431;SCHEMBL91389;Q27078056;Indisulam, >=98% (HPLC);DTXSID50168008;n-(3-chloro-1h-indol-7-yl)-4-sulfamoylbenzenesulfonamide;INDISULAM [MI];AC-36646;N~1~-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide
SMILES: ClC1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2N([H])S(C1C([H])=C([H])C(=C([H])C=1[H])S(N([H])[H])(=O)=O)(=O)=O
Formula: C14H12ClN3O4S2
M.Wt: 385.8458
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Indisulam (E7070) is potent, sulfonamide, cell-cycle inhibitor that possesses antiproliferative activities, causes decrease in the S phase fraction along with G1 and/or G2 accumulation in various cancer cell lines; causes blockade in the G1/S transition through inhibition of the activation of both cyclin-dependent kinase 2 and cyclin E, shows activity in multiple tumor types, most prominently in colon and lung cancer.Breast CancerPhase 2 Discontinued
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