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Cedazuridine

  Cat. No.:  DC20987   Featured
Chemical Structure
1141397-80-9
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More than 5000 active chemicals with high quality for research!
Field of application
Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies..
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1141397-80-9
Chemical Name: Cedazuridine
Synonyms: E7727;E-7727;E 7727
SMILES: O=C1N([C@H]2C(F)(F)[C@@H]([C@@H](CO)O2)O)CC[C@@H](O)N1
Formula: C9H14F2N2O5
M.Wt: 268.217
Purity: >95%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Cedazuridine (E7727) is a Cytidine Deaminase (CDA) inhibitor with an IC50 value of 0.4 μM[1].
Target: Cytidine Deaminase (CDA) :IC50: 0.4 μM (CDA)[1]
References: [1]. Ferraris D, et al. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem. 2014 Mar 27; 57(6):2582-8.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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