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Difamilast

  Cat. No.:  DC21445   Featured
Chemical Structure
937782-05-3
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More than 5000 active chemicals with high quality for research!
Field of application
Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 937782-05-3
Chemical Name: Difamilast
Synonyms: Difamilast;T3U32GLJ0F;Difamilast [USAN];Difamilast (JAN/USAN);MM36;GTPL9776;BDBM389126;USRE46792, 352;DB14987;example 352 [WO2007058338];D11314;N-[2-(4-difluoromethoxy-3-isopropoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide;N-((2-(4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl)-1,3-oxazol-4-yl)methyl)-2-ethoxybenzamide;N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide;Benzamide, N-((2-(4-(;N-[[2-[4-(Difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxybenzamide (ACI);MM 36;N-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)-2-ethoxybenzamide;OPA 15406
SMILES: O=C(C1C(OCC)=CC=CC=1)NCC1=COC(C2C=C(OC(C)C)C(OC(F)F)=CC=2)=N1
Formula: C23H24F2N2O5
M.Wt: 446.443873405457
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).  Dermatitis Phase 2 Clinical
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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