SBI-477 |cas 781628-99-7|DC Chemicals

Cas No.:	781628-99-7
Chemical Name:	SBI-477
Synonyms:	SMR000263903;MLS003914284;MLS000402240;HMS2530M10;Z27852835;3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-[2-(morpholin-4-yl)-2-oxoethoxy]benzamide;SBI-477
SMILES:	S1C([H])=C(C2C([H])=C([H])C(=C([H])C=2[H])OC([H])([H])[H])N=C1N([H])C(C1C([H])=C([H])C(=C(C=1[H])OC([H])([H])[H])OC([H])([H])C(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=O)=O
Formula:	C₂₄H₂₅N₃O₆S
M.Wt:	483.5368
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively; reduces expression of TXNIP and ARRDC4, negative regulators of insulin signaling, via deactivation of the transcription factor MondoA.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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