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BAY-1316957

  Cat. No.:  DC22013   Featured
Chemical Structure
1613264-40-6
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More than 5000 active chemicals with high quality for research!
Field of application
BAY-1316957 (BAY 1316957) is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist with IC50 of 15.3 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1613264-40-6
Chemical Name: BAY-1316957
Synonyms: 2-(9-Ethyl-6-methyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-4-methyl-1H-benzimidazole-5-carboxylic acid;BDBM261892;BAY 1316957;US9708311, 141;2-(9-Ethyl-6-methyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-4-methyl-1H-benzo[d]imidazole-5-carboxylic acid;2-(9-ethyl-6-methylcarbazol-3-yl)-1-(2-methoxyethyl)-4-methylbenzimidazole-5-carboxylic acid;BAY-1316957;bay1316957
SMILES: O(C)CCN1C2C=CC(C(=O)O)=C(C)C=2N=C1C1C=CC2=C(C=1)C1C=C(C)C=CC=1N2CC
Formula: C27H27N3O3
M.Wt: 441.5216
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: BAY-1316957 is a highly potent and selective EP4 receptor antagonist with an IC50 of 15.3 nM. Good oral bioavailability[1].
Target: IC50: 15.3 nM (EP4)[1]
References: [1]. Bäurle S, et al. Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis. J Med Chem. 2019 Mar 14;62(5):2541-2563.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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