Cas No.: | 51146-56-6 |
Chemical Name: | (S)-(+)-2-(4-Isobutylphenyl)propionic Acid |
Synonyms: | Dexibuprofen; Doctrin; L 669455; L-669,455, MK 233; MK-233; Dexibuprofen (free acid) |
SMILES: | O=C([C@@H](C)C1C=CC(CC(C)C)=CC=1)O |
Formula: | C13H18O2 |
M.Wt: | 206.285 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form; also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50=62 and 122 uM, respectively). |